Holter monitoring demonstrates that ventricular arrhythmias are common in cats with decompensated and compensated hypertrophic cardiomyopathy

Bartoszuk, U; Keene, B W; Toaldo, M B; Pereira, N; Summerfield, N; Novo Matos, J; Glaus, T M

Abstract

Arrhythmias can complicate cardiac disease in cats and are a potential cause of sudden death. The aim of this study was to evaluate the presence and nature of cardiac arrhythmias, and the potential correlation between plasma serum troponin I (cTnI) concentrations and the presence or severity of arrhythmias in cats with decompensated (dHCM) and compensated hypertrophic cardiomyopathy (cHCM). Forty one client-owned cats were studied: 16 with cHCM, 15 with dHCM and 10 healthy control cats. Physical examination, echocardiography, cTnI and 24-h Holter recordings were obtained in all cats and thoracic radiographs in cats with dHCM. Cats in both HCM groups were followed for 1 year after their initial Holter examination.

The median (range) number of ventricular premature complexes (VPCs) over 24 h was 867 (1–35,160) in cats with dHCM, 431 (0–18,919) in cats with cHCM and 2 (0–13) in healthy control cats. The median number of episodes of ventricular tachycardia (VTach) was 0 (0–1497) in dHCM and 0.5 (0–91) in cats with cHCM. The number of VPCs, VTach episodes and heart rate was not different between the HCM groups. Plasma serum troponin I was highest in the cats with dHCM, but there was no correlation between cTnI concentration and the number of arrhythmias. Thirteen of 31 cats with HCM died, but an association with the presence and complexity of ventricular arrhythmias was not observed. Compared to healthy cats, ventricular arrhythmias were common in cats with cHCM and dHCM, but neither presence nor complexity of arrhythmias could be linked to prognosis.

Citation

Bartoszuk, U., Keene, B. W., Toaldo, M. B., Pereira, N., Summerfield, N., Novo Matos, J., & Glaus, T. M. (2018). Holter monitoring demonstrates that ventricular arrhythmias are common in cats with decompensated and compensated hypertrophic cardiomyopathy. https://doi.org/10.1016/j.tvjl.2018.11.005

• Journal Article Type: Article
• Acceptance Date: Nov 7, 2018
• Publication Date: Nov 12, 2018
• Deposit Date: Nov 17, 2018
• Publicly Available Date: Nov 14, 2019
• Journal: VETERINARY JOURNAL
• Peer Reviewed: Peer Reviewed
• Volume: 243
• Pages: 21-25
• DOI: https://doi.org/10.1016/j.tvjl.2018.11.005
• Public URL: https://rvc-repository.worktribe.com/output/1385251