Pre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination following Toxin-Induced Spinal Cord Demyelination

Crawford, A H; Tripathi, R B; Foerster, S; McKenzie, I; Kougioumtzidou, E; Grist, M; Richardson, W D; Franklin, R J

doi:10.1016/j.ajpath.2015.11.005

All Outputs (5)

Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis (2017)
Journal Article
Crawford, A. H., Stoll, A. L., Sanchez-Masian, D., Shea, A., Michaels, J., Fraser, A. R., & Beltran, E. (2017). Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis. Journal of Veterinary Internal Medicine, 31(5), 1477-1486. https://doi.org/10.1111/jvim.14791

Background: Feline infectious peritonitis (FIP) is the most common infectious central nervous system (CNS) disease in the cat and is invariably fatal. Improved means of antemortem diagnosis is required to facilitate clinical decision making. Informat... Read More about Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis.

Surgical treatment of a paraspinal abscess with osteomyelitis and spinal cord compression in a rabbit (2017)
Journal Article
Crawford, A. H., Hedley, J., Lam, R. W., Drozdzynska, M. J., & De Decker, S. (2017). Surgical treatment of a paraspinal abscess with osteomyelitis and spinal cord compression in a rabbit. Journal of the American Veterinary Medical Association, 251(3), 340-344

MRI and clinical resolution of a suspected intracranial toxoplasma granuloma with medical treatment in a domestic short hair cat (2017)
Journal Article
Crawford, A. H., Drees, R., & Beltran, E. (2017). MRI and clinical resolution of a suspected intracranial toxoplasma granuloma with medical treatment in a domestic short hair cat. https://doi.org/10.1136/vetreccr-2017-000480

A two-year-old cat was presented with a left paradoxical vestibular syndrome. MRI of the brain revealed an extra-axial homogenously contrast enhancing mass in the region of the left caudal cerebellar peduncle. Toxoplasma serology was consistent with... Read More about MRI and clinical resolution of a suspected intracranial toxoplasma granuloma with medical treatment in a domestic short hair cat.

Clinical presentation and outcome of dogs treated medically or surgically for thoracolumbar intervertebral disc protrusion (2017)
Journal Article
Crawford, A. H., & De Decker, S. (2017). Clinical presentation and outcome of dogs treated medically or surgically for thoracolumbar intervertebral disc protrusion. Veterinary Record, 180(23), https://doi.org/10.1136/vr.103871

To date, few studies have investigated the clinical characteristics of thoracolumbar intervertebral disc protrusion (IVDP). The aim of this retrospective study was to evaluate the presentation and outcome of dogs receiving medical or surgical treatme... Read More about Clinical presentation and outcome of dogs treated medically or surgically for thoracolumbar intervertebral disc protrusion.

Pre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination following Toxin-Induced Spinal Cord Demyelination (2017)
Journal Article
Crawford, A. H., Tripathi, R. B., Foerster, S., McKenzie, I., Kougioumtzidou, E., Grist, M., …Franklin, R. J. (2017). Pre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination following Toxin-Induced Spinal Cord Demyelination. American Journal of Pathology, 186(3), 511-6. https://doi.org/10.1016/j.ajpath.2015.11.005

Remyelination is the regenerative response to demyelination. Although the oligodendrocyte progenitor is established as the major source of remyelinating cells, there is no conclusive evidence on whether mature, differentiated oligodendrocytes can als... Read More about Pre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination following Toxin-Induced Spinal Cord Demyelination.