All Outputs (192)

Structure, ontogeny and evolution of the patellar tendon in emus (Dromaius novaehollandiae) and other palaeognath birds (2015)
Journal Article
Regnault, S., Pitsillides, A. A., & Hutchinson, J. R. (2015). Structure, ontogeny and evolution of the patellar tendon in emus (Dromaius novaehollandiae) and other palaeognath birds. https://doi.org/10.7717/peerj.711

The patella (kneecap) exhibits multiple evolutionary origins in birds, mammals, and lizards, and is thought to increase the mechanical advantage of the knee extensor muscles. Despite appreciable interest in the specialized anatomy and locomotion of p... Read More about Structure, ontogeny and evolution of the patellar tendon in emus (Dromaius novaehollandiae) and other palaeognath birds.

Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations (2014)
Journal Article
Soper, R. J., Oguz, C., Emery, R., Pitsillides, A. A., & Hodges, S. J. (2014). Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations. Molecular Nutrition & Food Research, 58(8), 1658-1666. https://doi.org/10.1002/mnfr.201400063

The potential benefit of vitamin K as a therapeutic in osteoporosis is controversial and the vitamin K regimen being used clinically (45 mg/day) employs doses that are many times higher than required to ensure maximal gamma‐carboxylation of the vitam... Read More about Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations.

Modifications of Gait as Predictors of Natural Osteoarthritis Progression in STR/Ort Mice (2014)
Journal Article
Poulet, B., De Souza, R., Knights, C. B., Gentry, C., Wilson, A. M., Bevan, S., …Pitsillides, A. A. (2014). Modifications of Gait as Predictors of Natural Osteoarthritis Progression in STR/Ort Mice. https://doi.org/10.1002/art.38616

UDP-glucose 6-dehydrogenase (UGDH) (2014)
Book Chapter
Wegrowski, Y., & Pitsillides, A. A. (2014). UDP-glucose 6-dehydrogenase (UGDH). In Handbook of Glycosyltransferases and Related Genes (1425-1437). Springer

Hyaluronan synthesis and degradation in cartilage and bone
Journal Article
Bastow, E. R., Byers, S., Golub, S. B., Clarkin, C. E., Pitsillides, A. A., & Fosang, A. J. Hyaluronan synthesis and degradation in cartilage and bone. Cellular and Molecular Life Sciences, 65(3), 395-413. https://doi.org/10.1007/s00018-007-7360-z

Hyaluronan (HA) is a large but simple glycosaminoglycan composed of repeating D-glucuronic acid, beta 1-3 linked to N-acetyl-D-glucosamine beta 1-4, found in body fluids and tissues, in both intra- and extracellular compartments. Despite its structur... Read More about Hyaluronan synthesis and degradation in cartilage and bone.

Genetic selection for fast growth generates bone architecture characterised by enhanced periosteal expansion and limited consolidation of the cortices but a diminution in the early responses to mechanical loading
Journal Article
Rawlinson, S. C. F., Murray, D. H., Mosley, J. R., Wright, C. D. P., Bredl, J. C., Saxon, L. K., …Pitsillides, A. A. Genetic selection for fast growth generates bone architecture characterised by enhanced periosteal expansion and limited consolidation of the cortices but a diminution in the early responses to mechanical loading. BONE, 45(2), 357-366. https://doi.org/10.1016/j.bone.2009.04.243

DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO
Journal Article
Akbareian, S. E., Pitsillides, A. A., & McGonnell, I. M. DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO. Journal of Anatomy, 212(1), 85-85

Hyaluronan in joint cavitation
Conference Proceeding
Ward, A. C., Dowthwaite, G. P., & Pitsillides, A. A. Hyaluronan in joint cavitation

Influence of epitopes CD44v3 and CD44v6 in the invasive behavior of fibroblast-like synoviocytes derived from rheumatoid arthritic joints
Journal Article
Wibulswas, A., Croft, D., Pitsillides, A. A., Bacarese-Hamilton, I., McIntyre, P., Genot, E., & Kramer, I. M. Influence of epitopes CD44v3 and CD44v6 in the invasive behavior of fibroblast-like synoviocytes derived from rheumatoid arthritic joints. Arthritis and Rheumatism, 46(8), 2059-2064. https://doi.org/10.1002/art.10421

PROFILE ANALYSIS OF METAPHYSEAL TRABECULAR BONE IN RODENT OVARIECTOMY MODELS REVEALS A BIMODAL DOSE-DEPENDENT RESPONSE TO ADMINISTERED BONE ACTIVE AGENTS
Journal Article
Pitsillides, A. A., Salmon, P., Tivesten, A., Moverare-Skrtic, S., Ohlsson, C., Oste, L., …Fazzalari, N. PROFILE ANALYSIS OF METAPHYSEAL TRABECULAR BONE IN RODENT OVARIECTOMY MODELS REVEALS A BIMODAL DOSE-DEPENDENT RESPONSE TO ADMINISTERED BONE ACTIVE AGENTS. BONE, 44, 437. https://doi.org/10.1016/j.bone.2009.01.344

Mechanical strain and fluid movement both activate extracellular regulated kinase (ERK) in osteoblast-like cells but via different signaling pathways
Journal Article
Jessop, H. L., Rawlinson, S. C. F., Pitsillides, A. A., & Lanyon, L. E. Mechanical strain and fluid movement both activate extracellular regulated kinase (ERK) in osteoblast-like cells but via different signaling pathways. BONE, 31(1), 186-194. https://doi.org/10.1016/S8756-3282%2802%2900797-4

DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO
Journal Article
Akbareian, S. E., Thompson, I. R., Pitsillides, A. A., Fowkes, R. C., & McGonnell, I. M. DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO. Developmental Biology, 331(2), 252. https://doi.org/10.1016/j.ydbio.2009.05.276

Keratan sulfate epitopes exhibit a conserved distribution during joint development that remains undisclosed on the basis of glycosaminoglycan charge density
Journal Article
Kavanagh, E., Osborne, A. C., Ashhurst, D. E., & Pitsillides, A. A. Keratan sulfate epitopes exhibit a conserved distribution during joint development that remains undisclosed on the basis of glycosaminoglycan charge density

Joint immobilization reduces synovial fluid hyaluronan concentration and is accompanied by changes in the synovial intimal cell populations
Other
Pitsillides, A. A., Skerry, T. M., & Edwards, J. C. Joint immobilization reduces synovial fluid hyaluronan concentration and is accompanied by changes in the synovial intimal cell populations

Human osteoblasts' proliferative responses to strain and 17 beta-estradiol are mediated by the estrogen receptor and the receptor for insulin-like growth factor I
Journal Article
Cheng, M. Z., Rawlinson, S. C. F., Pitsillides, A. A., Zaman, G., Mohan, S., Baylink, D. J., & Lanyon, L. E. Human osteoblasts' proliferative responses to strain and 17 beta-estradiol are mediated by the estrogen receptor and the receptor for insulin-like growth factor I. Journal of Bone and Mineral Research, 17(4), 593-602. https://doi.org/10.1359/jbmr.2002.17.4.593

In vivo knee joint loading of Str/ort mice: distinguishing between load-induced and naturally occurring lesions
Journal Article
Poulet, B., & Pitsillides, A. A. In vivo knee joint loading of Str/ort mice: distinguishing between load-induced and naturally occurring lesions. International Journal of Experimental Pathology, 90(1), A64-A65

Short-term rigid and flaccid paralyses diminish growth of embryonic chick limbs and abrogate joint cavity formation but differentially preserve pre-cavitated joints
Journal Article
Osborne, A. C., Lamb, K. J., Lewthwaite, J. C., Dowthwaite, G. P., & Pitsillides, A. A. Short-term rigid and flaccid paralyses diminish growth of embryonic chick limbs and abrogate joint cavity formation but differentially preserve pre-cavitated joints

Increased Bone Mass, Altered Trabecular Architecture and Modified Growth Plate Organization in the Growing Skeleton of SOCS2 Deficient Mice
Journal Article
MacRae, V. E., Horvat, S., Pells, S. C., Dale, H., Collinson, R. S., Pitsillides, A. A., …Farquharson, C. Increased Bone Mass, Altered Trabecular Architecture and Modified Growth Plate Organization in the Growing Skeleton of SOCS2 Deficient Mice. Journal of Cellular Physiology, 218(2), 276-284. https://doi.org/10.1002/jcp.21593

THE BONE ANABOLIC EFFECT OF INTERMITTENT PARATHYROID HORMONE IS MODULATED BY VASORELAXATION
Journal Article
Gohin, S., Chenu, C., Pitsillides, A. A., Arnett, T., & Marenzana, M. THE BONE ANABOLIC EFFECT OF INTERMITTENT PARATHYROID HORMONE IS MODULATED BY VASORELAXATION. International Journal of Experimental Pathology, 95(3), A13-A14

The mRNA expression of prostaglandin E receptors EP2 and EP4 and the changes in glycosaminoglycans in the sheep cervix during the estrous cycle
Journal Article
Kershaw-Young, C. M., Khalid, M., McGowan, M. R., Pitsillides, A. A., & Scaramuzzi, R. J. The mRNA expression of prostaglandin E receptors EP2 and EP4 and the changes in glycosaminoglycans in the sheep cervix during the estrous cycle. Theriogenology, 72(2), 251-261. https://doi.org/10.1016/j.theriogenology.2009.02.018