All Outputs (2)

Dog leucocyte antigen (DLA) class II haplotypes and risk of canine diabetes mellitus in specific dog breeds (2020)
Journal Article
Denyer, A. L., Massey, J. P., Davison, L. J., Ollier, W. E. R., Catchpole, B., & Kennedy, L. J. (2020). Dog leucocyte antigen (DLA) class II haplotypes and risk of canine diabetes mellitus in specific dog breeds. Canine Medicine and Genetics, 7(1), 15. https://doi.org/10.1186/s40575-020-00093-9

Abstract: Background: Canine diabetes mellitus (DM) is a common endocrine disease in domestic dogs. A number of pathological mechanisms are thought to contribute to the aetiopathogenesis of relative or absolute insulin deficiency, including immune-me... Read More about Dog leucocyte antigen (DLA) class II haplotypes and risk of canine diabetes mellitus in specific dog breeds.

Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism (2020)
Journal Article
Boag, A. M., Short, A., Kennedy, L. J., Syme, H., Graham, P. A., & Catchpole, B. (2020). Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism. Canine Medicine and Genetics, 7(2), https://doi.org/10.1186/s40575-020-0081-4

Canine hypoadrenocorticism is an immune-mediated endocrinopathy that shares both clinical and pathophysiological similarities with Addison’s disease in humans. Several dog breeds are overrepresented in the disease population, suggesting that a geneti... Read More about Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism.