Endothelial cells as targets for chylomicron remnants
Journal Article
Dalla-Riva, J., Garonna, E., Elliott, J., Botham, K. M., & Wheeler-Jones, C. P. D. Endothelial cells as targets for chylomicron remnants. https://doi.org/10.1016/j.atherosclerosissup.2010.04.001
All Outputs (103)
INFLUENCE OF LIPID CONTENT AND OXIDATION STATE OF CHYLOMICRON REMNANTS ON ENDOTHELIAL CELL SIGNALLING AND FUNCTION
Journal Article
Dalla-Riva, J., Garonna, E., Elliott, J., Botham, K. M., & Wheeler-Jones, C. P. D. INFLUENCE OF LIPID CONTENT AND OXIDATION STATE OF CHYLOMICRON REMNANTS ON ENDOTHELIAL CELL SIGNALLING AND FUNCTION. https://doi.org/10.1016/j.atherosclerosissup.2010.04.039
SUPPRESSION OF NUCLEAR FACTOR-kappaB ACTIVITY IN MACROPHAGES BY CHYLOMICRON REMNANTS: MODULATION BY THE FATTY ACID COMPOSITION OF THE PARTICLES
Journal Article
De Pascale, C., Graham, V. S., Fowkes, R. C., Wheeler-Jones, C. P. D., & Botham, K. M. SUPPRESSION OF NUCLEAR FACTOR-kappaB ACTIVITY IN MACROPHAGES BY CHYLOMICRON REMNANTS: MODULATION BY THE FATTY ACID COMPOSITION OF THE PARTICLES
Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium
Journal Article
Hamdulay, S. S., Wang, B. F., Birdsey, G. M., Ali, F., Dumont, O., Evans, P. C., …Mason, J. C. Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium. Free Radical Biology and Medicine, 48(8), 1013-1023. https://doi.org/10.1016/j.freeradbiomed.2010.01.017
The effect of estradiol on COX-2, EP2, and EP4 mRNA expression and the extracellular matrix in the cervix of the hypogonadotrophic, ovariectomized ewe
Journal Article
Kershaw-Young, C. M., Scaramuzzi, R. J., McGowan, M. R., Pitsillides, A. A., Wheeler-Jones, C. P. D., & Khalid, M. The effect of estradiol on COX-2, EP2, and EP4 mRNA expression and the extracellular matrix in the cervix of the hypogonadotrophic, ovariectomized ewe. Theriogenology, 73(5), 620-628. https://doi.org/10.1016/j.theriogenology.2009.10.018
Paracrine Stimulation of Endothelial Cell Motility and Angiogenesis by Platelet-Derived Deoxyribose-1-Phosphate
Journal Article
Pula, G., Garonna, E., Dunn, W. B., Hirano, M., Pizzorno, G., Campanella, M., …Wheeler-Jones, C. P. D. Paracrine Stimulation of Endothelial Cell Motility and Angiogenesis by Platelet-Derived Deoxyribose-1-Phosphate. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(12), 2631-8. https://doi.org/10.1161/atvbaha.110.215855
C-type natriuretic peptide regulation of guanosine-3',5'-cyclic monophosphate production in human endothelial cells
Journal Article
Rautureau, Y., Gowers, I., Wheeler-Jones, C. P. D., & Baxter, G. F. C-type natriuretic peptide regulation of guanosine-3',5'-cyclic monophosphate production in human endothelial cells. https://doi.org/10.1111/j.1474-8673.2009.00449.x
Targeting hyaluronan of the endothelial glycocalyx for therapeutic intervention
Journal Article
Wheeler-Jones, C. P. D., Farrar, C. E., & Pitsillides, A. A. Targeting hyaluronan of the endothelial glycocalyx for therapeutic intervention
Endotoxin-induced activation of equine digital vein endothelial cells: Role of p38 MAPK
Journal Article
Brooks, A. C., Menzies-Gow, N. J., Wheeler-Jones, C. P. D., Bailey, S. R., Cunningham, F. M., & Elliott, J. Endotoxin-induced activation of equine digital vein endothelial cells: Role of p38 MAPK. Veterinary Immunology and Immunopathology, 129(3-4), 174-180. https://doi.org/10.1016/j.vetimm.2008.11.008
Regulation of platelet activating factor-induced equine platelet activation by intracellular kinases
Journal Article
Brooks, A. C., Menzies-Gow, N. J., Wheeler-Jones, C. P. D., Bailey, S. R., Elliott, J., & Cunningham, F. M. Regulation of platelet activating factor-induced equine platelet activation by intracellular kinases. Journal of Veterinary Pharmacology and Therapeutics, 32(2), 189-196. https://doi.org/10.1111/j.1365-2885.2008.01020.xLipopolysaccharide (LPS) can activate equine platelets directly or indirectly, via leukocyte-derived platelet activating factor (PAF). Thromboxane (Tx) production by LPS-stimulated equine platelets requires p38 MAPK and this kinase has been suggested... Read More about Regulation of platelet activating factor-induced equine platelet activation by intracellular kinases.
Suppression of nuclear factor-kappaB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles
Journal Article
De Pascale, C., Graham, V., Fowkes, R. C., Wheeler-Jones, C. P. D., & Botham, K. M. Suppression of nuclear factor-kappaB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles. FEBS Journal, 276(19), 5689-5702. https://doi.org/10.1111/j.1742-4658.2009.07260.x
CELECOXIB ENHANCES ENDOTHELIAL HO-1 EXPRESSION AND ACTIVITY: A NOVEL MECHANISM OF VASCULAR CYTOPROTECTION
Journal Article
Hamdulay, S. S., Wang, B. F., Haskard, D. O., Wheeler-Jones, C. P. D., & Mason, J. CELECOXIB ENHANCES ENDOTHELIAL HO-1 EXPRESSION AND ACTIVITY: A NOVEL MECHANISM OF VASCULAR CYTOPROTECTION
Expression of blood coagulation factors on monocytes after exposure to TNF-treated endothelium in a novel whole blood model of arterial flow
Journal Article
Macey, M. G., Wolf, S. I., Wheeler-Jones, C. P. D., & Lawson, C. Expression of blood coagulation factors on monocytes after exposure to TNF-treated endothelium in a novel whole blood model of arterial flow. Journal of Immunological Methods, 350(1-2), 133-141. https://doi.org/10.1016/j.jim.2009.08.007
Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, alpha T3-1 and L beta T2 gonadotroph cells
Journal Article
Thompson, I. R., Chand, A. N., Jonas, K. C., Burrin, J. M., Steinhelper, M. E., Wheeler-Jones, C. P. D., …Fowkes, R. C. Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, alpha T3-1 and L beta T2 gonadotroph cells. Journal of Endocrinology, 203(2), 215-229. https://doi.org/10.1677/joe-09-0189
Protease-activated receptors, cyclo-oxygenases and pro-angiogenic signalling in endothelial cells
Journal Article
Wheeler-Jones, C. P. D., Farrar, C. E., & Garonna, E. Protease-activated receptors, cyclo-oxygenases and pro-angiogenic signalling in endothelial cells. Biochemical Society Transactions, 37, 1179-1183. https://doi.org/10.1042/bst0371179
Mechanical strain and estrogen activate estrogen receptor alpha in bone cells
Journal Article
Jessop, H. L., Sjoberg, M., Cheng, M. Z., Zaman, G., Wheeler-Jones, C. P. D., & Lanyon, L. E. Mechanical strain and estrogen activate estrogen receptor alpha in bone cells. Journal of Bone and Mineral Research, 16(6), 1045-1055. https://doi.org/10.1359/jbmr.2001.16.6.1045
Agonist-specific cross talk between ERKs and p38(mapk) regulates PGI(2) synthesis in endothelium
Journal Article
Houliston, R. A., Pearson, J. D., & Wheeler-Jones, C. P. D. Agonist-specific cross talk between ERKs and p38(mapk) regulates PGI(2) synthesis in endothelium
sPLA(2) cooperates with cPLA(2)alpha to regulate prostacyclin synthesis in human endothelial cells
Journal Article
Houliston, R. A., & Wheeler-Jones, C. P. D. sPLA(2) cooperates with cPLA(2)alpha to regulate prostacyclin synthesis in human endothelial cells. Biochemical and Biophysical Research Communications, 287(4), 881-887. https://doi.org/10.1006/bbrc.2001.5681
Chylomicron remnants: mediators of endothelial dysfunction?
Conference Proceeding
Wheeler-Jones, C. P. D. Chylomicron remnants: mediators of endothelial dysfunction?
A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion
Journal Article
Persaud, S. J., Roderigo-Milne, H. M., Squires, P. E., Sugden, D., Wheeler-Jones, C. P. D., Marsh, P. J., …Jones, P. M. A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion. Diabetes, 51(1), 98-104