Disturbed flow promotes endothelial senescence via a p53-dependent pathway
(2014)
Journal Article
Warboys, C. M., De Luca, A., Amini, N., Luong, L., Duckles, H., Hsiao, S., …Evans, P. C. (2014). Disturbed flow promotes endothelial senescence via a p53-dependent pathway. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(5), 985-995. https://doi.org/10.1161/ATVBAHA.114.303415
Although atherosclerosis is associated with systemic risk factors such as age, high cholesterol, and obesity, plaque formation occurs predominately at branches and bends that are exposed to disturbed patterns of blood flow. The molecular mechanisms t... Read More about Disturbed flow promotes endothelial senescence via a p53-dependent pathway.