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All Outputs (202)

Conformation-associated health in pet rabbits in the UK: A VetCompass cohort study (2024)
Journal Article
O'Neill, D., Williams, A., Brodbelt, D. C., Church, D. B., & Hedley, J. (2024). Conformation-associated health in pet rabbits in the UK: A VetCompass cohort study. Herpetological Conservation and Biology, https://doi.org/10.1002/vetr.4396

Abstract Background Domestic rabbit breeds vary substantially from the wild rabbit body type. However, little is known about how the conformation of pet rabbits influences their health. Methods Data were extracted from VetCompass anonymised clinical... Read More about Conformation-associated health in pet rabbits in the UK: A VetCompass cohort study.

Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study (2024)
Journal Article
O'Neill, D., Diaz-Ordaz, K., Pegram, C., Brodbelt, D. C., Chang, Y., Hall, J. L., & Church, D. B. (2024). Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study. Herpetological Conservation and Biology, 19(7), e0305526. https://doi.org/10.1371/journal.pone.0305526

There is growing evidence supporting clinically important associations between age at neutering in bitches and subsequent urinary incontinence (UI), although much of this evidence to date is considered weak. Target trial emulation is an innovative ap... Read More about Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study.

Life tables of annual life expectancy and risk factors for mortality in cats in the UK (2024)
Journal Article
O'Neill, D., Kendy Tzu-yun, T., Dave C, B., & David B, C. (2024). Life tables of annual life expectancy and risk factors for mortality in cats in the UK. Herpetological Conservation and Biology, 26(5), 1098612X241234556. https://doi.org/10.1177/1098612x241234556

ObjectivesThe aims of the present study were to generate the first life tables for the UK companion cat population overall as well as broken down by sex and breed status, and to quantify associations between mortality and traits such as sex, neuter s... Read More about Life tables of annual life expectancy and risk factors for mortality in cats in the UK.

The epidemiology of tick infestation in dog breeds in the UK (2024)
Journal Article
O'Neill, D., Komutrattananon, R., Hartley, A., Brodbelt, D., & Church, D. (2024). The epidemiology of tick infestation in dog breeds in the UK. Herpetological Conservation and Biology, https://doi.org/10.1111/jsap.13727

Objectives: The purpose of this study is to report the prevalence and risk factors for tick infestation in
dogs in the UK based on anonymised electronic patient records.
Materials and Methods: Clinical records of dogs under veterinary care in 2016... Read More about The epidemiology of tick infestation in dog breeds in the UK.

Target Trial Emulation: Does surgical versus non-surgical management of cranial cruciate ligament rupture in dogs cause different outcomes? (2024)
Journal Article
Pegram, C., Diaz-Ordaz, K., Brodbelt, D. C., Chang, Y., von Hekkel, A. F., Wu, C., …O’Neill, D. G. (2024). Target Trial Emulation: Does surgical versus non-surgical management of cranial cruciate ligament rupture in dogs cause different outcomes?. Preventive Veterinary Medicine, 106165. https://doi.org/10.1016/j.prevetmed.2024.106165

Target trial emulation applies design principles from randomised controlled trials to the analysis of observational data for causal inference and is increasingly used within human epidemiology. Using anonymised veterinary clinical data from the VetCo... Read More about Target Trial Emulation: Does surgical versus non-surgical management of cranial cruciate ligament rupture in dogs cause different outcomes?.

Feline Comorbidities: Hypersomatotropism-induced diabetes in cats (2024)
Journal Article
Scudder, C., & Church, D. (2024). Feline Comorbidities: Hypersomatotropism-induced diabetes in cats. Journal of Feline Medicine and Surgery, 26(2), https://doi.org/10.1177/1098612x241226690

Practical relevance:
Diabetes mellitus is the second-most common feline endocrinopathy, affecting an estimated 1/200 cats. While the underlying causes vary, around 15-25% of cats with diabetes mellitus develop the condition secondarily to progressiv... Read More about Feline Comorbidities: Hypersomatotropism-induced diabetes in cats.

Demography, common disorders and mortality of Shih Tzu dogs under primary veterinary care in the UK (2024)
Journal Article
O'Neill, D., Brodbelt, D., Church, D., & Dale, F. (2024). Demography, common disorders and mortality of Shih Tzu dogs under primary veterinary care in the UK. Herpetological Conservation and Biology, 11(1), 2. https://doi.org/10.1186/s40575-023-00135-y

Background Shih Tzus are a popular dog breed in the UK although there is relatively little reported information
on their health. This study aimed to characterise the demography, common disorders and mortality of Shih Tzus
under primary veterinary c... Read More about Demography, common disorders and mortality of Shih Tzu dogs under primary veterinary care in the UK.

Epidemiology of mammary tumours in bitches under veterinary care in the UK in 2016 (2023)
Journal Article
Varney, D., Varney, D., O'Neill, D., O'Neill, D., O'Neill, M., O'Neill, M., …Brodbelt, D. (2023). Epidemiology of mammary tumours in bitches under veterinary care in the UK in 2016. Veterinary Record, https://doi.org/10.1002/vetr.3054

BackgroundThere is limited information on the epidemiology of canine mammary tumours. This study aimed to estimate the incidence and risk factors for mammary tumours in UK bitches. MethodsA nested case-control study was conducted within VetCompass to... Read More about Epidemiology of mammary tumours in bitches under veterinary care in the UK in 2016.

High-frequency ultrasound biomicroscopy findings of the skin of dogs with atopic dermatitis (2023)
Journal Article
Mantis, P., Sofou, E., Aleksandrova, S., Badulescu, E., Church, D., Lloyd, D., …Saridomichelakis, M. (2023). High-frequency ultrasound biomicroscopy findings of the skin of dogs with atopic dermatitis. Veterinary Dermatology, https://doi.org/10.1111/vde.13169

Background: The high-frequency ultrasonographic appearance of skin of dogs with atopic dermatitis (cAD) has not been described.Objectives: To compare high-frequency ultrasonographic findings among lesional, macroscopically nonlesional skin of dogs wi... Read More about High-frequency ultrasound biomicroscopy findings of the skin of dogs with atopic dermatitis.

Assessment of glucocorticoid and antibiotic exposure as risk factors for diabetes mellitus in selected dog breeds attending UK primary-care clinics (2023)
Journal Article
Davison, L., O'Neill, D., Brodbelt, D., Church, D., & Heeley, A. (in press). Assessment of glucocorticoid and antibiotic exposure as risk factors for diabetes mellitus in selected dog breeds attending UK primary-care clinics. Veterinary Record, https://doi.org/10.1002/vetr.2785

Background: Diabetes mellitus (DM) is an important endocrine disorder in dogs resulting from interactions between both genetic (non-environmental) and environmental factors. This study aimed to explore prior exposure to glucocorticoid or antibiotic t... Read More about Assessment of glucocorticoid and antibiotic exposure as risk factors for diabetes mellitus in selected dog breeds attending UK primary-care clinics.

Risk factors for unilateral cranial cruciate ligament rupture diagnosis and for clinical management in dogs under primary veterinary care in the UK (2023)
Journal Article
Pegram, C., Brodbelt, D., Diaz-Ordaz, K., Chang, Y., Frykfors von Hekkel, A., Church, D., & O'Neill, D. (2023). Risk factors for unilateral cranial cruciate ligament rupture diagnosis and for clinical management in dogs under primary veterinary care in the UK. The Veterinary Journal, https://doi.org/10.1016/j.tvjl.2023.105952

This study aimed to evaluate demographic risk factors associated with unilateral cranial cruciate ligament (CCL) rupture diagnosis and to explore demographic and clinical risk factors associated with management of unilateral CCL rupture in dogs under... Read More about Risk factors for unilateral cranial cruciate ligament rupture diagnosis and for clinical management in dogs under primary veterinary care in the UK.

Agreeing Language in Veterinary Endocrinology (ALIVE): Diabetes mellitus - a modified Delphi-method-based system to create consensus disease definitions (2022)
Journal Article
ESVE SCE Membership, Niessen, S., Bjornvad, C., Church, D., Davison, L., Esteban-Saltiveri, D., …Thuroczy, J. (2022). Agreeing Language in Veterinary Endocrinology (ALIVE): Diabetes mellitus - a modified Delphi-method-based system to create consensus disease definitions. The Veterinary Journal, 289, https://doi.org/10.1016/j.tvjl.2022.105910

English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections (2022)
Journal Article
O’Neill, D. G., Skipper, A., Packer, R. M. A., Lacey, C., Church, D. B., Brodbelt, D. C., & Pegram, C. (2022). English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections. Canine Medicine and Genetics, 9(1), https://doi.org/10.1186/s40575-022-00118-5

Background
The English Bulldog has risen sharply in popularity over the past decade but its distinctive and extreme conformation is linked to several serious health conditions. Using multivariable analysis of anonymised veterinary clinical data from... Read More about English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections.

Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom (2022)
Journal Article
Tzu-yun Teng, K., Brodbelt, D., Pegram, C., Church, D., & O’Neill, D. (2022). Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom. Scientific Reports, 12(1), 6415. https://doi.org/10.1038/s41598-022-10341-6

A life table is a tabulated expression of life expectancy and mortality-related information at specified ages in a given population. This study applied the VetCompass Programme to generate life tables for the UK dog population both overall and broken... Read More about Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom.