TLR5 Risk-Associated Haplotype for Canine Inflammatory Bowel Disease Confers Hyper-Responsiveness to Flagellin
Journal Article
Kathrani, A., Holder, A. L., Catchpole, B., Alvarez, L., Simpson, K., Werling, D., & Allenspach, K. TLR5 Risk-Associated Haplotype for Canine Inflammatory Bowel Disease Confers Hyper-Responsiveness to Flagellin. PLoS ONE, 7(1), e30117. https://doi.org/10.1371/journal.pone.0030117
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Macrophage Sub-Populations and the Lipoxin A(4) Receptor Implicate Active Inflammation during Equine Tendon Repair
Journal Article
Dakin, S. G., Werling, D., Hibbert, A., Abayasekara, D. R. E., Young, N. J., Smith, R. K. W., & Dudhia, J. Macrophage Sub-Populations and the Lipoxin A(4) Receptor Implicate Active Inflammation during Equine Tendon Repair. PLoS ONE, 7(2), e32333. https://doi.org/10.1371/journal.pone.0032333
Inflamm-Aging and Arachadonic Acid Metabolite Differences with Stage of Tendon Disease
Journal Article
Dakin, S. G., Dudhia, J., Werling, N. J., Werling, D., Abayasekara, D. R. E., & Smith, R. K. W. Inflamm-Aging and Arachadonic Acid Metabolite Differences with Stage of Tendon Disease. PLoS ONE, 7(11), e48978. https://doi.org/10.1371/journal.pone.0048978
Expression of trefoil factor genes in the duodenum and colon of dogs with inflammatory bowel disease and healthy dogs
Journal Article
Schmitz, S., Hill, S., Werling, D., & Allenspach, K. Expression of trefoil factor genes in the duodenum and colon of dogs with inflammatory bowel disease and healthy dogs. Veterinary Immunology and Immunopathology, 151(1-2), 168-172. https://doi.org/10.1016/j.vetimm.2012.10.009
Comparison of TNF alpha responses induced by Toll-like receptor ligands and probiotic Enterococcus faecium in whole blood and peripheral blood mononuclear cells of healthy dogs
Journal Article
Schmitz, S., Henrich, M., Neiger, R., Werling, D., & Allenspach, K. Comparison of TNF alpha responses induced by Toll-like receptor ligands and probiotic Enterococcus faecium in whole blood and peripheral blood mononuclear cells of healthy dogs. Veterinary Immunology and Immunopathology, 153(1-2), 170-174. https://doi.org/10.1016/j.vetimm.2013.02.014
Stimulation of Duodenal Biopsies and Whole Blood from Dogs with Food-Responsive Chronic Enteropathy and Healthy Dogs with Toll-Like Receptor Ligands and Probiotic Enterococcus faecium
Journal Article
Schmitz, S., Henrich, M., Neiger, R., Werling, D., & Allenspach, K. Stimulation of Duodenal Biopsies and Whole Blood from Dogs with Food-Responsive Chronic Enteropathy and Healthy Dogs with Toll-Like Receptor Ligands and Probiotic Enterococcus faecium. Scandinavian Journal of Immunology, https://doi.org/10.1111/sji.12186
Lack of Correlation between Mucosal Immunoglobulin A-positive Plasma Cell Numbers and TLR5 Genotypes in German Shepherd Dogs with Idiopathic Chronic Enteropathy
Journal Article
Lee, A., Kathrani, A., Priestnall, S. L., Smith, K. C., Werling, D., & Allenspach, K. (in press). Lack of Correlation between Mucosal Immunoglobulin A-positive Plasma Cell Numbers and TLR5 Genotypes in German Shepherd Dogs with Idiopathic Chronic Enteropathy. Journal of Comparative Pathology, 152(2-3), 201-5. https://doi.org/10.1016/j.jcpa.2015.01.002
Effects of Ex-Vivo and In-Vivo Treatment with Probiotics on the Inflammasome in Dogs with Chronic Enteropathy
Journal Article
Schmitz, S., Werling, D., & Allenspach, K. (in press). Effects of Ex-Vivo and In-Vivo Treatment with Probiotics on the Inflammasome in Dogs with Chronic Enteropathy. PLoS ONE, 10(3), e0120779. https://doi.org/10.1371/journal.pone.0120779Inflammasomes coordinate the maturation of IL-1β and IL-18 in response to danger signals. They are vital for maintenance of intestinal homeostasis and have been linked to chronic intestinal inflammation in humans. Probiotics have been advocated as tr... Read More about Effects of Ex-Vivo and In-Vivo Treatment with Probiotics on the Inflammasome in Dogs with Chronic Enteropathy.
Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor
Journal Article
Dutton, L. C., Dudhia, J., Catchpole, B., Hodhkiss-Geere, H., Werling, D., & Connolly, D. J. (in press). Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor. https://doi.org/10.1038/s41598-018-31569-1derived cells (CDCs) are a cardiac progenitor cell population, which have been shown to possess cardiac regenerative properties and can improve heart function in a variety of cardiac diseases. Studies in large animal models have predominantly focusse... Read More about Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor.
Role of sugars in surface microbe-host interactions and immune reaction modulation
Journal Article
Lloyd, D. H., Viac, J., Werling, D., Reme, C. A., & Gatto, H. Role of sugars in surface microbe-host interactions and immune reaction modulation. Veterinary Dermatology, 18(4), 197-204. https://doi.org/10.1111/j.1365-3164.2007.00594.x