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Vaccination with transgenic Eimeria tenella expressing Eimeria maxima AMA1 and IMP1 confers partial protection against high level E. maxima challenge in a broiler model of coccidiosis. (2020)
Journal Article
Pastor-Fernández, I., Sungwon, K., Marugán-Hernández, V., Soutter, F., Tomley, F., & Blake, D. (2020). Vaccination with transgenic Eimeria tenella expressing Eimeria maxima AMA1 and IMP1 confers partial protection against high level E. maxima challenge in a broiler model of coccidiosis. Parasites and Vectors,

Poultry coccidiosis is a parasitic enteric disease with a highly negative impact on chicken production. In-feed chemoprophylaxis remains the primary method of control, but the increasing ineffectiveness of anticoccidial drugs, and potential future re... Read More about Vaccination with transgenic Eimeria tenella expressing Eimeria maxima AMA1 and IMP1 confers partial protection against high level E. maxima challenge in a broiler model of coccidiosis..

Poultry Coccidiosis: Design and Interpretation of Vaccine Studies (2020)
Journal Article
Soutter, F., Werling, D., Tomley, F. M., & Blake, D. P. (2020). Poultry Coccidiosis: Design and Interpretation of Vaccine Studies. Frontiers in Veterinary Science, 7, https://doi.org/10.3389/fvets.2020.00101

Eimeria infection impacts upon chicken welfare and economic productivity of the poultry sector. Live coccidiosis vaccines for chickens have been available for almost 70 years, but the requirement to formulate blends of oocysts from multiple Eimeria s... Read More about Poultry Coccidiosis: Design and Interpretation of Vaccine Studies.

Associations between clinical canine leishmaniosis and multiple vector-borne co-infections: a case-control serological study (2019)
Journal Article
Attipa, C., Solano-Gallego, L., Leutenegger, C. M., Papasouliotis, K., Soutter, F., Balzer, J., Carver, S., Buch, J. S., & Tasker, S. (2019). Associations between clinical canine leishmaniosis and multiple vector-borne co-infections: a case-control serological study. BMC Veterinary Research, 15(331), https://doi.org/10.1186/s12917-019-2083-6

Dogs that have clinical leishmaniosis (ClinL), caused by the parasite Leishmania infantum, are commonly co-infected with other pathogens, especially vector-borne pathogens (VBP). A recent PCR-based study found that ClinL dogs are more likely to be ad... Read More about Associations between clinical canine leishmaniosis and multiple vector-borne co-infections: a case-control serological study.

An investigation of polymorphisms in innate and adaptive immune response genes in canine leishmaniosis (2019)
Journal Article
Soutter, F., Solano-Gallego, L., Attipa, C., Gradoni, L., Fiorentino, E., Foglia Manzillo, V., Oliva, G., Tasker, S., Helps, C., & Catchpole, B. (2019). An investigation of polymorphisms in innate and adaptive immune response genes in canine leishmaniosis. Veterinary Parasitology, 269, 34-41. https://doi.org/10.1016/j.vetpar.2019.04.011

The outcome of infection with Leishmania infantum in dogs is variable, which is thought to be due to the nature of the immune response mounted by the host. As a consequence, the clinical signs and severity of canine leishmaniosis vary between individ... Read More about An investigation of polymorphisms in innate and adaptive immune response genes in canine leishmaniosis.

Inconsistent MHC class II association in Beagles experimentally infected with Leishmania infantum (2018)
Journal Article
Soutter, F., Martorell, S., Solano-Gallego, L., & Catchpole, B. (2018). Inconsistent MHC class II association in Beagles experimentally infected with Leishmania infantum. https://doi.org/10.1016/j.tvjl.2018.03.001

The clinical outcome of Leishmania infantum infection in dogs varies from subclinical infection to severe disease. Researchers attribute this variability in clinical manifestations to the ability of the immune response to limit pathogen multiplicatio... Read More about Inconsistent MHC class II association in Beagles experimentally infected with Leishmania infantum.

Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185 (2018)
Journal Article
Holder, A. L., Jones, G., Soutter, F., Palmer, D. B., Aspinall, R., & Catchpole, B. (2018). Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185. Developmental and Comparative Immunology, 81, 244-251. https://doi.org/10.1016/j.dci.2017.12.008

Interleukin-7 (IL-7) and its receptor (IL-7R) are essential for T cell development in the thymus, and changes in the IL-7/IL-7R pathway have been implicated in age-associated thymic involution which results in a reduction of naïve T cell output. The... Read More about Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185.

Canine tick-borne pathogens in Cyprus and a unique canine case of multiple co-infections (2017)
Journal Article
Attipa, C., Hicks, C. A. E., Barker, E. N., Christodoulou, V., Neofytou, K., Mylonakis, M. E., Siarkou, V. I., Vingopoulou, E. I., Soutter, F., Chochlakis, D., Psaroulaki, A., Papasouliotis, K., & Tasker, S. (2017). Canine tick-borne pathogens in Cyprus and a unique canine case of multiple co-infections. Ticks and Tick-borne Diseases, 8(3), 341-346. https://doi.org/10.1016/j.ttbdis.2016.12.006

Single Nucleotide Polymorphisms in Major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs (2016)
Journal Article
Peiravan, A., Allenspach, K., Boag, A. M., Soutter, F., Holder, A. L., Catchpole, B., Kennedy, L. J., Werling, D., & Procoli, F. (2016). Single Nucleotide Polymorphisms in Major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs. Veterinary Immunology and Immunopathology, 182, 101-105. https://doi.org/10.1016/j.vetimm.2016.10.012