ERRATUM TO: VIABILITY OF EQUINE MESENCHYMAL STEM CELLS DURING TRANSPORT AND IMPLANTATION
(2016)
Journal Article
Garvican, E. R., Cree, S., Bull, L., Smith, R. K. W., & Dudhia, J. (2016). ERRATUM TO: VIABILITY OF EQUINE MESENCHYMAL STEM CELLS DURING TRANSPORT AND IMPLANTATION. https://doi.org/10.1186/s13287-016-0423-z
All Outputs (93)
Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries (2016)
Journal Article
Garvican, E. R., Salavati, M., Smith, R. K. W., & Dudhia, J. (2016). Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries. Connective Tissue Research, 58(5), 438-446. https://doi.org/10.1080/03008207.2016.1245726Aim: The purpose of this study was to investigate the effect of normal synovial fluid (SF) on exposed endogenous tendon-derived cells (TDC) and engrafted mesenchymal stem cells (MSCs) within the tendon extracellular matrix. Methods: Explants from eq... Read More about Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries.
Modulation of mesenchymal stem cell genotype and phenotype by extracellular matrix proteins (2016)
Journal Article
Clements, L. E., Garvican, E. R., Dudhia, J., & Smith, R. K. W. (2016). Modulation of mesenchymal stem cell genotype and phenotype by extracellular matrix proteins. Connective Tissue Research, 57(6), 443-453. https://doi.org/10.1080/03008207.2016.1215442
Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing (2016)
Journal Article
Zaman, G., Staines, K. A., Farquharson, C., Newton, P. T., Dudhia, J., Chenu, C., …Dhoot, G. K. (2016). Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing. Histochemistry and Cell Biology, 145(1), 67-79. https://doi.org/10.1007/s00418-015-1365-8
Investigating the Postmortem Molecular Biology of Cartilage and its Potential Forensic Applications (2015)
Journal Article
Bolton, S. N., Whitehead, M. P., Dudhia, J., Baldwin, T. C., & Sutton, R. (2015). Investigating the Postmortem Molecular Biology of Cartilage and its Potential Forensic Applications. Journal of Forensic Sciences, 60(4), 1061-67. https://doi.org/10.1111/1556-4029.12764This study investigated the postmortem molecular changes that articular cartilage undergoes following burial. Fresh pig trotters were interred in 30‐cm‐deep graves at two distinct locations exhibiting dissimilar soil environments for up to 42 days. E... Read More about Investigating the Postmortem Molecular Biology of Cartilage and its Potential Forensic Applications.
Low Density Lipoprotein Receptor-related Protein 1 (LRP1)-mediated Endocytic Clearance of a Disintegrin and Metalloproteinase with Thrombospondin Motifs-4 (ADAMTS-4) FUNCTIONAL DIFFERENCES OF NON-CATALYTIC DOMAINS OF ADAMTS-4 AND ADAMTS-5 IN LRP1 BINDING (2014)
Journal Article
Yamamoto, K., Owen, K., Parker, A. E., Scilabra, S. D., Dudhia, J., Strickland, D. K., …Nagase, H. (2014). Low Density Lipoprotein Receptor-related Protein 1 (LRP1)-mediated Endocytic Clearance of a Disintegrin and Metalloproteinase with Thrombospondin Motifs-4 (ADAMTS-4) FUNCTIONAL DIFFERENCES OF NON-CATALYTIC DOMAINS OF ADAMTS-4 AND ADAMTS-5 IN LRP1 BINDING. Journal of Biological Chemistry, 289(10), 6462-6474. https://doi.org/10.1074/jbc.M113.545376Degradation of the cartilage proteoglycan aggrecan is an early event in the development of osteoarthritis, and a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4) and ADAMTS-5 are considered to be the major aggrecan-degrading... Read More about Low Density Lipoprotein Receptor-related Protein 1 (LRP1)-mediated Endocytic Clearance of a Disintegrin and Metalloproteinase with Thrombospondin Motifs-4 (ADAMTS-4) FUNCTIONAL DIFFERENCES OF NON-CATALYTIC DOMAINS OF ADAMTS-4 AND ADAMTS-5 IN LRP1 BINDING.
Proteomic Analysis of Tendon Extracellular Matrix Reveals Disease Stage- specific Fragmentation and Differential Cleavage of COMP ( Cartilage Oligomeric Matrix Protein) (2014)
Journal Article
Dakin, S. G., Smith, R. K. W., Heinegard, D., Onnerfjord, P., Khabut, A., & Dudhia, J. (2014). Proteomic Analysis of Tendon Extracellular Matrix Reveals Disease Stage- specific Fragmentation and Differential Cleavage of COMP ( Cartilage Oligomeric Matrix Protein). Journal of Biological Chemistry, 289(8), 4919-4927. https://doi.org/10.1074/jbc.M113.511972During inflammatory processes the extracellular matrix (ECM) is extensively remodeled, and many of the constituent components are released as proteolytically cleaved fragments. These degradative processes are better documented for inflammatory joint... Read More about Proteomic Analysis of Tendon Extracellular Matrix Reveals Disease Stage- specific Fragmentation and Differential Cleavage of COMP ( Cartilage Oligomeric Matrix Protein).
A preliminary study on the effect of wounding on transforming growth factor-ß1 and cartilage oligomeric matrix protein concentrations in the skin of horses (2011)
Journal Article
Dart, A. J., Dart, C. M., Dudhia, J., Perkins, N., Canfield, P. J., & Smith, R. K. W. (2011). A preliminary study on the effect of wounding on transforming growth factor-ß1 and cartilage oligomeric matrix protein concentrations in the skin of horses. Veterinary Surgery, 40(1), 59-65. https://doi.org/10.1111/j.1532-950X.2010.00756.x
Equine Embryonic Stem Cell-Derived Tenocytes are Insensitive to a Combination of Inflammatory Cytokines and Have Distinct Molecular Responses Compared to Primary Tenocytes (0000)
Journal Article
Smith, E. J., Beaumont, R. E., Dudhia, J., & Guest, D. J. (0000). Equine Embryonic Stem Cell-Derived Tenocytes are Insensitive to a Combination of Inflammatory Cytokines and Have Distinct Molecular Responses Compared to Primary Tenocytes. Stem Cell Reviews and Reports, https://doi.org/10.1007/s12015-024-10693-8Tissue fibrosis following tendon injury is a major clinical problem due to the increased risk of re-injury and limited treatment options; however, its mechanism remains unclear. Evidence suggests that insufficient resolution of inflammation contribut... Read More about Equine Embryonic Stem Cell-Derived Tenocytes are Insensitive to a Combination of Inflammatory Cytokines and Have Distinct Molecular Responses Compared to Primary Tenocytes.
Beneficial effects of autologous bone marrow-derived mesenchymal stem cells in naturally occurring tendinopathy
Journal Article
Smith, R. K. W., Werling, N. J., Dakin, S. G., Alam, R., Goodship, A. E., & Dudhia, J. Beneficial effects of autologous bone marrow-derived mesenchymal stem cells in naturally occurring tendinopathy. PLoS ONE, 8(9), e75697. https://doi.org/10.1371/journal.pone.0075697
DEVELOPMENT OF A NEO-EPITOPE ASSAY FOR THE DETECTION OF TENDON DISEASE
Journal Article
Smith, R. K. W., Onnerfjord, P., Dudhia, J., Damidez, S., Dakin, S. G., & Heinegard, D. DEVELOPMENT OF A NEO-EPITOPE ASSAY FOR THE DETECTION OF TENDON DISEASE. International Journal of Experimental Pathology, 94(1), A10-A10
INTRA-OPERATIVE MAPPING OF ARTICULAR CARTILAGE DEGENERATION WITH RAMAN ARTHROSPECTROSCOPY
Journal Article
Nunn, A. D. G., Strachan, R. K., Firth, S., Draper, E. R. C., McMillan, P. F., & Dudhia, J. INTRA-OPERATIVE MAPPING OF ARTICULAR CARTILAGE DEGENERATION WITH RAMAN ARTHROSPECTROSCOPY. International Journal of Experimental Pathology, 94(1), A19-A20
Implantation of bone marrow-derived mesenchymal stem cells demonstrates improved outcome in horses with overstrain injury of the superficial digital flexor tendon.
Journal Article
Godwin, E. E., Young, N. J., Dudhia, J., Beamish, I. C., & Smith, R. K. W. Implantation of bone marrow-derived mesenchymal stem cells demonstrates improved outcome in horses with overstrain injury of the superficial digital flexor tendon. Equine Veterinary Journal, 44(1), 25-32. https://doi.org/10.1111/j.2042-3306.2011.00363.x
Cell-based Therapies for Tendon and Ligament Injuries
Journal Article
Alves, A. G. L., Stewart, A. A., Dudhia, J., Kasashima, Y., Goodship, A. E., & Smith, R. K. W. Cell-based Therapies for Tendon and Ligament Injuries. https://doi.org/10.1016/j.cveq.2011.06.001
COMPARISON OF HUMAN MESENCHYMAL STEM CELLS EXPANSION IN BASAL AND SERUM SUPPLEMENTED MEDIA
Journal Article
Chowdhury, M. W. H., Carr, A., Smith, R. K. W., & Dudhia, J. COMPARISON OF HUMAN MESENCHYMAL STEM CELLS EXPANSION IN BASAL AND SERUM SUPPLEMENTED MEDIA. International Journal of Experimental Pathology, 92(6), A35-A35
SYNTHESIS VS. DEGRADATION OF PROSTAGLANDIN E(2): A COMPARISON OF GENE EXPRESSION IN NORMAL AND INJURED EQUINE TENDON
Journal Article
Dakin, S. G., Dudhia, J., Young, N. J., Clegg, P. D., & Smith, R. K. W. SYNTHESIS VS. DEGRADATION OF PROSTAGLANDIN E(2): A COMPARISON OF GENE EXPRESSION IN NORMAL AND INJURED EQUINE TENDON. International Journal of Experimental Pathology, 92(3), A19-A19
The relationship between in vivo limb and in vitro tendon mechanics after injury: A potential novel clinical tool for monitoring tendon repair
Journal Article
Dakin, S. G., Jespers, K., Warner, S. M., O'Hara, L. K., Dudhia, J., Goodship, A. E., …Smith, R. K. W. The relationship between in vivo limb and in vitro tendon mechanics after injury: A potential novel clinical tool for monitoring tendon repair. Equine Veterinary Journal, 43(4), 418-423. https://doi.org/10.1111/j.2042-3306.2010.00303.x
FATE OF MESENCHYMAL STEM CELLS FOLLOWING DIFFERENT IN VIVO ADMINISTRATION ROUTES IN REPAIR OF TENDON INJURIES
Journal Article
Dudhia, J., Becerra, P., Valdes, M. A., Neves, F., Hartman, N. G., Fiske-Jackson, A. R., & Smith, R. W. K. FATE OF MESENCHYMAL STEM CELLS FOLLOWING DIFFERENT IN VIVO ADMINISTRATION ROUTES IN REPAIR OF TENDON INJURIES. International Journal of Experimental Pathology, 92(6), A38-A38
EFFECTS OF MESENCHYMAL STEM CELLS ADHERED TO EQUINE FLEXOR TENDON EXPLANTS IN-VITRO
Journal Article
Garvican, E. R., Dudhia, J., & Smith, R. K. W. EFFECTS OF MESENCHYMAL STEM CELLS ADHERED TO EQUINE FLEXOR TENDON EXPLANTS IN-VITRO. International Journal of Experimental Pathology, 92(6), A31-A31
TRACKING OF MESENCHYMAL STEM CELLS IN TENDON INJURIES FOLLOWING IN VIVO ADMINISTRATION
Journal Article
Dudhia, J., Becerra, P., Valdes, M. A., Neves, F., Hartman, N. G., Fiske-Jackson, A. R., & Smith, R. K. W. TRACKING OF MESENCHYMAL STEM CELLS IN TENDON INJURIES FOLLOWING IN VIVO ADMINISTRATION. Journal of Tissue Engineering and Regenerative Medicine, 6, 154-154