ERRATUM TO: VIABILITY OF EQUINE MESENCHYMAL STEM CELLS DURING TRANSPORT AND IMPLANTATION
(2016)
Journal Article
Garvican, E. R., Cree, S., Bull, L., Smith, R. K. W., & Dudhia, J. (2016). ERRATUM TO: VIABILITY OF EQUINE MESENCHYMAL STEM CELLS DURING TRANSPORT AND IMPLANTATION. https://doi.org/10.1186/s13287-016-0423-z
All Outputs (72)
Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries (2016)
Journal Article
Garvican, E. R., Salavati, M., Smith, R. K. W., & Dudhia, J. (2016). Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries. Connective Tissue Research, 58(5), 438-446. https://doi.org/10.1080/03008207.2016.1245726Aim: The purpose of this study was to investigate the effect of normal synovial fluid (SF) on exposed endogenous tendon-derived cells (TDC) and engrafted mesenchymal stem cells (MSCs) within the tendon extracellular matrix.
Methods: Explants from eq... Read More about Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries.
Modulation of mesenchymal stem cell genotype and phenotype by extracellular matrix proteins (2016)
Journal Article
Clements, L. E., Garvican, E. R., Dudhia, J., & Smith, R. K. W. (2016). Modulation of mesenchymal stem cell genotype and phenotype by extracellular matrix proteins. Connective Tissue Research, 57(6), 443-453. https://doi.org/10.1080/03008207.2016.1215442
Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing (2016)
Journal Article
Zaman, G., Staines, K. A., Farquharson, C., Newton, P. T., Dudhia, J., Chenu, C., …Dhoot, G. K. (2016). Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing. Histochemistry and Cell Biology, 145(1), 67-79. https://doi.org/10.1007/s00418-015-1365-8
Investigating the Postmortem Molecular Biology of Cartilage and its Potential Forensic Applications (2015)
Journal Article
Bolton, S. N., Whitehead, M. P., Dudhia, J., Baldwin, T. C., & Sutton, R. (2015). Investigating the Postmortem Molecular Biology of Cartilage and its Potential Forensic Applications. Journal of Forensic Sciences, 60(4), 1061-67. https://doi.org/10.1111/1556-4029.12764This study investigated the postmortem molecular changes that articular cartilage undergoes following burial. Fresh pig trotters were interred in 30‐cm‐deep graves at two distinct locations exhibiting dissimilar soil environments for up to 42 days. E... Read More about Investigating the Postmortem Molecular Biology of Cartilage and its Potential Forensic Applications.
Low Density Lipoprotein Receptor-related Protein 1 (LRP1)-mediated Endocytic Clearance of a Disintegrin and Metalloproteinase with Thrombospondin Motifs-4 (ADAMTS-4) FUNCTIONAL DIFFERENCES OF NON-CATALYTIC DOMAINS OF ADAMTS-4 AND ADAMTS-5 IN LRP1 BINDING (2014)
Journal Article
Yamamoto, K., Owen, K., Parker, A. E., Scilabra, S. D., Dudhia, J., Strickland, D. K., …Nagase, H. (2014). Low Density Lipoprotein Receptor-related Protein 1 (LRP1)-mediated Endocytic Clearance of a Disintegrin and Metalloproteinase with Thrombospondin Motifs-4 (ADAMTS-4) FUNCTIONAL DIFFERENCES OF NON-CATALYTIC DOMAINS OF ADAMTS-4 AND ADAMTS-5 IN LRP1 BINDING. Journal of Biological Chemistry, 289(10), 6462-6474. https://doi.org/10.1074/jbc.M113.545376Degradation of the cartilage proteoglycan aggrecan is an early event in the development of osteoarthritis, and a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4) and ADAMTS-5 are considered to be the major aggrecan-degrading... Read More about Low Density Lipoprotein Receptor-related Protein 1 (LRP1)-mediated Endocytic Clearance of a Disintegrin and Metalloproteinase with Thrombospondin Motifs-4 (ADAMTS-4) FUNCTIONAL DIFFERENCES OF NON-CATALYTIC DOMAINS OF ADAMTS-4 AND ADAMTS-5 IN LRP1 BINDING.
Proteomic Analysis of Tendon Extracellular Matrix Reveals Disease Stage- specific Fragmentation and Differential Cleavage of COMP ( Cartilage Oligomeric Matrix Protein) (2014)
Journal Article
Dakin, S. G., Smith, R. K. W., Heinegard, D., Onnerfjord, P., Khabut, A., & Dudhia, J. (2014). Proteomic Analysis of Tendon Extracellular Matrix Reveals Disease Stage- specific Fragmentation and Differential Cleavage of COMP ( Cartilage Oligomeric Matrix Protein). Journal of Biological Chemistry, 289(8), 4919-4927. https://doi.org/10.1074/jbc.M113.511972During inflammatory processes the extracellular matrix (ECM) is extensively remodeled, and many of the constituent components are released as proteolytically cleaved fragments. These degradative processes are better documented for inflammatory joint... Read More about Proteomic Analysis of Tendon Extracellular Matrix Reveals Disease Stage- specific Fragmentation and Differential Cleavage of COMP ( Cartilage Oligomeric Matrix Protein).
A preliminary study on the effect of wounding on transforming growth factor-ß1 and cartilage oligomeric matrix protein concentrations in the skin of horses (2011)
Journal Article
Dart, A. J., Dart, C. M., Dudhia, J., Perkins, N., Canfield, P. J., & Smith, R. K. W. (2011). A preliminary study on the effect of wounding on transforming growth factor-ß1 and cartilage oligomeric matrix protein concentrations in the skin of horses. Veterinary Surgery, 40(1), 59-65. https://doi.org/10.1111/j.1532-950X.2010.00756.x
Equine Embryonic Stem Cell-Derived Tenocytes are Insensitive to a Combination of Inflammatory Cytokines and Have Distinct Molecular Responses Compared to Primary Tenocytes (0000)
Journal Article
Smith, E. J., Beaumont, R. E., Dudhia, J., & Guest, D. J. (0000). Equine Embryonic Stem Cell-Derived Tenocytes are Insensitive to a Combination of Inflammatory Cytokines and Have Distinct Molecular Responses Compared to Primary Tenocytes. Stem Cell Reviews and Reports, https://doi.org/10.1007/s12015-024-10693-8Tissue fibrosis following tendon injury is a major clinical problem due to the increased risk of re-injury and limited treatment options; however, its mechanism remains unclear. Evidence suggests that insufficient resolution of inflammation contribut... Read More about Equine Embryonic Stem Cell-Derived Tenocytes are Insensitive to a Combination of Inflammatory Cytokines and Have Distinct Molecular Responses Compared to Primary Tenocytes.
Increased Cartilage Oligomeric Matrix Protein Concentrations in Equine Digital Flexor Tendon Sheath Synovial Fluid Predicts Intrathecal Tendon Damage
Journal Article
Smith, M. R. W., Wright, I. M., Minshall, G. J., Dudhia, J., Verheyen, K. L. P., Heinegard, D., & Smith, R. K. W. Increased Cartilage Oligomeric Matrix Protein Concentrations in Equine Digital Flexor Tendon Sheath Synovial Fluid Predicts Intrathecal Tendon Damage. Veterinary Surgery, 40(1), 54-58. https://doi.org/10.1111/j.1532-950X.2010.00751.x
Age-related differences in prostaglandin E-2 synthesis by equine cartilage explants and synoviocytes
Journal Article
Briston, L., Dudhia, J., & Lees, P. Age-related differences in prostaglandin E-2 synthesis by equine cartilage explants and synoviocytes. Journal of Veterinary Pharmacology and Therapeutics, 33(3), 268-276. https://doi.org/10.1111/j.1365-2885.2009.01131.x
Identification and Clonal Characterisation of a Progenitor Cell Sub-Population in Normal Human Articular Cartilage
Journal Article
Williams, R., Khan, I. M., Richardson, K., Nelson, L., McCarthy, H. E., Analbelsi, T., …Archer, C. W. Identification and Clonal Characterisation of a Progenitor Cell Sub-Population in Normal Human Articular Cartilage. PLoS ONE, 5(10), e13246. https://doi.org/10.1371/journal.pone.0013246
Notochordal cell produce and assemble extracellular matrix in a distinct manner, which may be responsible for the maintenance of healthy nucleus pulposus
Journal Article
Cappello, R., Bird, J. L. E., Pfeiffer, D. U., Bayliss, M. T., & Dudhia, J. Notochordal cell produce and assemble extracellular matrix in a distinct manner, which may be responsible for the maintenance of healthy nucleus pulposus. Spine, 31(8), 873-882. https://doi.org/10.1097/01.brs.0000209302.00820.fd
Mesenchymal stem cells modulate release of matrix proteins from tendon surfaces in vitro: a potential beneficial therapeutic effect
Journal Article
Garvican, E. R., Dudhia, J., Alves, A. L., Clements, L. E., Du Plessis, F., & Smith, R. K. W. Mesenchymal stem cells modulate release of matrix proteins from tendon surfaces in vitro: a potential beneficial therapeutic effect. Regenerative Medicine, 9(3), 295-308. https://doi.org/10.2217/rme.14.7
The relationship between in vivo limb and in vitro tendon mechanics after injury: A potential novel clinical tool for monitoring tendon repair
Journal Article
Dakin, S. G., Jespers, K., Warner, S. M., O'Hara, L. K., Dudhia, J., Goodship, A. E., …Smith, R. K. W. The relationship between in vivo limb and in vitro tendon mechanics after injury: A potential novel clinical tool for monitoring tendon repair. Equine Veterinary Journal, 43(4), 418-423. https://doi.org/10.1111/j.2042-3306.2010.00303.x
Aging enhances a mechanically-induced reduction in tendon strength by an active process involving matrix metalloproteinase activity
Journal Article
Dudhia, J., Scott, C. M., Draper, E. R. C., Heinegard, D., Pitsillides, A. A., & Smith, R. K. W. Aging enhances a mechanically-induced reduction in tendon strength by an active process involving matrix metalloproteinase activity. Aging Cell, 6(4), 547-556. https://doi.org/10.1111/j.1474-9726.2007.00307.x
Modification of the Composition of Articular Cartilage Collagen Fibrils with Increasing Age
Journal Article
Vaughan-Thomas, A., Dudhia, J., Bayliss, M., Kadler, K., & Duance, V. Modification of the Composition of Articular Cartilage Collagen Fibrils with Increasing Age. Connective Tissue Research, 49(5), 374-382. https://doi.org/10.1080/03008200802325417Recent studies have identified a range of interactions between type IX collagen and other cartilage matrix components. To determine the extent to which these interactions are important in maintaining the integrity of ageing articular cartilage, we an... Read More about Modification of the Composition of Articular Cartilage Collagen Fibrils with Increasing Age.
Membrane Type 1 Matrix Metalloproteinase Is a Crucial Promoter of Synovial Invasion in Human Rheumatoid Arthritis
Journal Article
Miller, M. C., Manning, H. B., Jain, A., Troeberg, L., Dudhia, J., Essex, D., …Itoh, Y. Membrane Type 1 Matrix Metalloproteinase Is a Crucial Promoter of Synovial Invasion in Human Rheumatoid Arthritis. Arthritis and Rheumatism, 60(3), 686-697. https://doi.org/10.1002/art.24331
Stem cells in veterinary medicine - attempts at regenerating equine tendon after injury
Journal Article
Richardson, L. E., Dudhia, J., Clegg, P. D., & Smith, R. K. W. Stem cells in veterinary medicine - attempts at regenerating equine tendon after injury. Trends in Biotechnology, 25(9), 409-416. https://doi.org/10.1016/j.tibtech.2007.07.009
Age-related changes in the composition, the molecular stoichiometry and the stability of proteoglycan aggregates extracted from human articular cartilage
Journal Article
Wells, T., Davidson, C., Morgelin, M., Bird, J. L. E., Bayliss, M. T., & Dudhia, J. Age-related changes in the composition, the molecular stoichiometry and the stability of proteoglycan aggregates extracted from human articular cartilage. Biochemical Journal, 370, 69-79