All Outputs (14)

Heterogeneity of proteome dynamics between connective tissue phases of adult tendon (2020)
Journal Article
Choi, H., Simpson, D., Wang, D., Prescott, M., Pitsillides, A. A., Dudhia, J., …Thorpe, C. T. (2020). Heterogeneity of proteome dynamics between connective tissue phases of adult tendon. eLife, 9, https://doi.org/10.7554/elife.55262

Maintenance of connective tissue integrity is fundamental to sustain function, requiring protein turnover to repair damaged tissue. However, connective tissue proteome dynamics remain largely undefined, as do differences in turnover rates of individu... Read More about Heterogeneity of proteome dynamics between connective tissue phases of adult tendon.

Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing (2016)
Journal Article
Zaman, G., Staines, K. A., Farquharson, C., Newton, P. T., Dudhia, J., Chenu, C., …Dhoot, G. K. (2016). Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing. Histochemistry and Cell Biology, 145(1), 67-79. https://doi.org/10.1007/s00418-015-1365-8

Metalloproteinase and tissue inhibitor of metalloproteinase expression in the murine STR/ort model of osteoarthritis
Journal Article
Flannelly, J., Chambers, M. G., Dudhia, J., Hembry, R. M., Murphy, G., Mason, R. M., & Bayliss, M. T. Metalloproteinase and tissue inhibitor of metalloproteinase expression in the murine STR/ort model of osteoarthritis. Osteoarthritis and Cartilage, 10(9), 722-733. https://doi.org/10.1053/joca.2002.0818

Protease-activated receptors upregulate cyclooxygenase-2 expression in human endothelial cells
Journal Article
Houliston, R. A., Keogh, R. J., Sugden, D., Dudhia, J., Carter, T. D., & Wheeler-Jones, C. P. D. Protease-activated receptors upregulate cyclooxygenase-2 expression in human endothelial cells. Thrombosis and Haemostasis, 88(2), 321-28

Age-related changes in the response of human articular cartilage to IL-1 alpha and transforming growth factor-beta (TGF-beta) - Chondrocytes exhibit a diminished sensitivity to TGF-beta
Journal Article
Hickery, M. S., Bayliss, M. T., Dudhia, J., Lewthwaite, J. C., Edwards, J. C. W., & Pitsillides, A. A. Age-related changes in the response of human articular cartilage to IL-1 alpha and transforming growth factor-beta (TGF-beta) - Chondrocytes exhibit a diminished sensitivity to TGF-beta. Journal of Biological Chemistry, 278(52), 53063-53071. https://doi.org/10.1074/jbc.M209632200

Aging enhances a mechanically-induced reduction in tendon strength by an active process involving matrix metalloproteinase activity
Journal Article
Dudhia, J., Scott, C. M., Draper, E. R. C., Heinegard, D., Pitsillides, A. A., & Smith, R. K. W. Aging enhances a mechanically-induced reduction in tendon strength by an active process involving matrix metalloproteinase activity. Aging Cell, 6(4), 547-556. https://doi.org/10.1111/j.1474-9726.2007.00307.x

THE INFLUENCE OF AGEING IN TENDON HOMEOSTASIS AND THE RISK OF TENDON INJURY
Journal Article
Smith, R. K. W., Dudhia, J., Scott, C. M., Draper, E., May, S. A., & Pitsillides, A. A. THE INFLUENCE OF AGEING IN TENDON HOMEOSTASIS AND THE RISK OF TENDON INJURY. International Journal of Experimental Pathology, 89(3), A25-A25

Inflamm-Aging and Arachadonic Acid Metabolite Differences with Stage of Tendon Disease
Journal Article
Dakin, S. G., Dudhia, J., Werling, N. J., Werling, D., Abayasekara, D. R. E., & Smith, R. K. W. Inflamm-Aging and Arachadonic Acid Metabolite Differences with Stage of Tendon Disease. PLoS ONE, 7(11), e48978. https://doi.org/10.1371/journal.pone.0048978

Macrophage Sub-Populations and the Lipoxin A(4) Receptor Implicate Active Inflammation during Equine Tendon Repair
Journal Article
Dakin, S. G., Werling, D., Hibbert, A., Abayasekara, D. R. E., Young, N. J., Smith, R. K. W., & Dudhia, J. Macrophage Sub-Populations and the Lipoxin A(4) Receptor Implicate Active Inflammation during Equine Tendon Repair. PLoS ONE, 7(2), e32333. https://doi.org/10.1371/journal.pone.0032333

The relationship between in vivo limb and in vitro tendon mechanics after injury: A potential novel clinical tool for monitoring tendon repair
Journal Article
Dakin, S. G., Jespers, K., Warner, S. M., O'Hara, L. K., Dudhia, J., Goodship, A. E., …Smith, R. K. W. The relationship between in vivo limb and in vitro tendon mechanics after injury: A potential novel clinical tool for monitoring tendon repair. Equine Veterinary Journal, 43(4), 418-423. https://doi.org/10.1111/j.2042-3306.2010.00303.x

EVIDENCE FOR DIFFERENTIAL REGULATION OF PROTEOGLYCANS AND COLLAGEN IN RESPONSE TO CYCLICAL STRAIN IN TENDON
Journal Article
Avella, C. S., Dudhia, J., Young, N. J., Goodship, A. E., & Smith, R. K. W. EVIDENCE FOR DIFFERENTIAL REGULATION OF PROTEOGLYCANS AND COLLAGEN IN RESPONSE TO CYCLICAL STRAIN IN TENDON. International Journal of Experimental Pathology, 91(2), A26-A27

Age-related differences in prostaglandin E-2 synthesis by equine cartilage explants and synoviocytes
Journal Article
Briston, L., Dudhia, J., & Lees, P. Age-related differences in prostaglandin E-2 synthesis by equine cartilage explants and synoviocytes. Journal of Veterinary Pharmacology and Therapeutics, 33(3), 268-276. https://doi.org/10.1111/j.1365-2885.2009.01131.x

EVALUATION OF BONE MARROW MESENCHYMAL STEM CELL THERAPY FOR TENDON REGENERATION IN A LARGE ANIMAL MODEL
Journal Article
Young, N. J., Dudhia, J., Goodship, A. E., & Smith, R. K. W. EVALUATION OF BONE MARROW MESENCHYMAL STEM CELL THERAPY FOR TENDON REGENERATION IN A LARGE ANIMAL MODEL. International Journal of Experimental Pathology, 91(2), A20-A20

The STR/ort mouse and its use as a model of osteoarthritis
Journal Article
Mason, R. M., Chambers, M. G., Flannelly, J., Gaffen, J. D., Dudhia, J., & Bayliss, M. T. The STR/ort mouse and its use as a model of osteoarthritis. Osteoarthritis and Cartilage, 9(2), 85-91