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Population genetics of Oncomelania hupensis snails, intermediate hosts of Schistosoma japonium, from emerging, re-emerging or established habitats within China (2019)
Journal Article
Qiu, C., Lu, D., Deng, Y., Zou, H., Liang, Y., & Webster, J. P. (2019). Population genetics of Oncomelania hupensis snails, intermediate hosts of Schistosoma japonium, from emerging, re-emerging or established habitats within China. Acta Tropica, 197, 105048. https://doi.org/10.1016/j.actatropica.2019.105048

Schistosomiasis remains one of the world’s most significant neglected tropical diseases, second only to malaria in terms of socioeconomic impact. In 2014, China proposed the goal of schistosomiasis japonicum elimination by 2025. However, one major ch... Read More about Population genetics of Oncomelania hupensis snails, intermediate hosts of Schistosoma japonium, from emerging, re-emerging or established habitats within China.

Uncooked fish consumption among those at risk of Opisthorchis viverrini infection in central Thailand (2019)
Journal Article
Suwannahitatorn, P., Webster, J. P., Riley, S., Mungthin, M., & Donnelly, C. A. (2019). Uncooked fish consumption among those at risk of Opisthorchis viverrini infection in central Thailand. PLoS ONE, 14(1), e0211540. https://doi.org/10.1371/journal.pone.0211540

In contrast to northern and northeastern Thailand, central Thailand was believed not to be endemic for Opisthorchis viverrini (OV). Fieldwork conducted in a rural area of central Thailand revealed that the prevalence and incidence were relatively hig... Read More about Uncooked fish consumption among those at risk of Opisthorchis viverrini infection in central Thailand.

Rodents of Senegal and their role as intermediate hosts of Hydatigera spp. (Cestoda: Taeniidae) (2018)
Journal Article
Catalano, S., Bâ, K., Diouf, N., Léger, E., Verocai, G., & Webster, J. P. (2018). Rodents of Senegal and their role as intermediate hosts of Hydatigera spp. (Cestoda: Taeniidae). Parasitology, 146(3), 299-304. https://doi.org/10.1017/S0031182018001427

Hydatigera (Cestoda: Taeniidae) is a recently resurrected genus including species seldom investigated in sub-Saharan Africa. We surveyed wild small mammal populations in the areas of Richard Toll and Lake Guiers, Senegal, with the objective to evalua... Read More about Rodents of Senegal and their role as intermediate hosts of Hydatigera spp. (Cestoda: Taeniidae).

Phylogenetic relationships within the Opisthorchis viverrini species complex with specific analysis of O. viverrini sensu lato from Sakon Nakhon, Thailand by mitochondrial and nuclear DNA sequencing (2018)
Journal Article
Pitaksakulrat, O., Webster, B. L., Webster, J. P., Laha, T., Saijuntha, W., Lamberton, P. H. L., …Sithithaworn, P. (2018). Phylogenetic relationships within the Opisthorchis viverrini species complex with specific analysis of O. viverrini sensu lato from Sakon Nakhon, Thailand by mitochondrial and nuclear DNA sequencing. https://doi.org/10.1016/j.meegid.2018.04.022

The liver fluke Opisthorchis viverrini sensu lato causes serious public-health problems in Northeast Thailand and Southeast Asian countries. A hypothesis has been proposed that O. viverrini represents a species complex with varying levels of genetic... Read More about Phylogenetic relationships within the Opisthorchis viverrini species complex with specific analysis of O. viverrini sensu lato from Sakon Nakhon, Thailand by mitochondrial and nuclear DNA sequencing.

The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni (2018)
Journal Article
Viana, M., Faust, C. L., Haydon, D. T., Webster, J. P., & Lamberton, P. H. L. (2018). The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni. Evolutionary Applications, 11(3), 488-500. https://doi.org/10.1111/eva.12558

Natural selection acts on all organisms, including parasites, to maximize reproductive fitness. Drug resistance traits are often associated with life-history costs in the absence of treatment. Schistosomiasis control programmes rely on mass drug admi... Read More about The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni.

Opportunities and challenges for modelling epidemiological and evolutionary dynamics in a multihost, multiparasite system: Zoonotic hybrid schistosomiasis in West Africa (2018)
Journal Article
Borlase, A., Webster, J. P., & Rudge, J. W. (2018). Opportunities and challenges for modelling epidemiological and evolutionary dynamics in a multihost, multiparasite system: Zoonotic hybrid schistosomiasis in West Africa. Evolutionary Applications, 11(4), 501-515. https://doi.org/10.1111/eva.12529

Multihost multiparasite systems are evolutionarily and ecologically dynamic, which presents substantial trans‐disciplinary challenges for elucidating their epidemiology and designing appropriate control. Evidence for hybridizations and introgressions... Read More about Opportunities and challenges for modelling epidemiological and evolutionary dynamics in a multihost, multiparasite system: Zoonotic hybrid schistosomiasis in West Africa.

Rodents as natural hosts of zoonotic Schistosoma species and hybrids: an epidemiological and evolutionary perspective from West Africa (2018)
Journal Article
Catalano, S., Sène, M., Diouf, N. D., Fall, C. B., Borlase, A., Léger, E., …Webster, J. P. (2018). Rodents as natural hosts of zoonotic Schistosoma species and hybrids: an epidemiological and evolutionary perspective from West Africa. Journal of Infectious Diseases, 218(3), 429-433. https://doi.org/10.1093/infdis/jiy029

The complex multi-host disease dynamics of schistosomiasis and Schistosoma spp., including the emergence of zoonotic parasite hybrids, remain largely unexplored in West Africa. We elucidated the role of wild small mammals as reservoir for zoonotic Sc... Read More about Rodents as natural hosts of zoonotic Schistosoma species and hybrids: an epidemiological and evolutionary perspective from West Africa.

Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme (2017)
Journal Article
Gower, C. M., Gehre, F., Marques, S. R., Lamberton, P. H. L., Lwambo, N. J., & Webster, J. P. (2017). Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme. https://doi.org/10.1186/s13071-017-2533-6

We conducted combined in vitro PZQ efficacy testing with population genetic analyses of S. mansoni collected from children from two schools in 2010, five years after the introduction of a National Control Programme. Children at one school had receive... Read More about Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme.

Who acquires infection from whom and how? Disentangling multi-host and multi-mode transmission dynamics in the 'elimination' era (2017)
Journal Article
Webster, J. P., Borlase, A. M., & Rudge, J. W. (2017). Who acquires infection from whom and how? Disentangling multi-host and multi-mode transmission dynamics in the 'elimination' era. Philosophical Transactions of the Royal Society B: Biological Sciences, 372(1719), https://doi.org/10.1098/rstb.2016.0091

Multi-host infectious agents challenge our abilities to understand, predict and manage disease dynamics. Within this, many infectious agents are also able to use, simultaneously or sequentially, multiple modes of transmission. Furthermore, the relati... Read More about Who acquires infection from whom and how? Disentangling multi-host and multi-mode transmission dynamics in the 'elimination' era.

The evolution of transmission mode (2017)
Journal Article
Antonovics, J., Wilson, A. J., Forbes, M. R., Hauffe, H. C., Kallio, E. R., Leggett, H. C., …Webster, J. P. (2017). The evolution of transmission mode. Philosophical Transactions of the Royal Society B: Biological Sciences, 372(1719), https://doi.org/10.1098/rstb.2016.0083

This article reviews research on the evolutionary mechanisms leading to different transmission modes. Such modes are often under genetic control of the host or the pathogen, and often in conflict with each other via trade-offs. Transmission modes may... Read More about The evolution of transmission mode.

Development and evaluation of a Markov model to predict changes in schistosomiasis prevalence in response to praziquantel treatment: a case study of Schistosoma mansoni in Uganda and Mali (2016)
Journal Article
Deol, A., Webster, J. P., Walker, M., Basáñez, M., Hollingsworth, T. D., Fleming, F. M., …French, M. D. (2016). Development and evaluation of a Markov model to predict changes in schistosomiasis prevalence in response to praziquantel treatment: a case study of Schistosoma mansoni in Uganda and Mali. https://doi.org/10.1186/s13071-016-1824-7