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Using a Whole Genome Co- expression Network to Inform the Functional Characterisation of Predicted Genomic Elements from Mycobacterium tuberculosis Transcriptomic Data (2023)
Journal Article
Stiens, J., Yi Tan, Y., Joyce, R., Arnvig, K. B., Kendall, S. L., & Nobeli, I. (in press). Using a Whole Genome Co- expression Network to Inform the Functional Characterisation of Predicted Genomic Elements from Mycobacterium tuberculosis Transcriptomic Data. Molecular Microbiology, https://doi.org/10.1111/mmi.15055

A whole genome co-expression network was created using Mycobacterium tuberculosis transcriptomic data from publicly available RNA-sequencing experiments covering a wide variety of experimental conditions. The network includes expressed regions with... Read More about Using a Whole Genome Co- expression Network to Inform the Functional Characterisation of Predicted Genomic Elements from Mycobacterium tuberculosis Transcriptomic Data.

Common Traits Spark the Mitophagy/Xenophagy Interplay (2018)
Journal Article
Singh, A., Kendall, S. L., & Campanella, M. (2018). Common Traits Spark the Mitophagy/Xenophagy Interplay. Frontiers in Physiology, 9, https://doi.org/10.3389/fphys.2018.01172

Selective autophagy contributes to the wellbeing of eukaryotic cells by recycling cellular components, disposing damaged organelles, and removing pathogens, amongst others. Both the quality control process of selective mitochondrial autophagy (Mitoph... Read More about Common Traits Spark the Mitophagy/Xenophagy Interplay.

Isolation and Potential for Transmission of Mycobacterium bovis at Human–livestock–wildlife Interface of the Serengeti Ecosystem, Northern Tanzania (2017)
Journal Article
Katale, B. Z., Mbugi, E. V., Siame, K. K., Keyyu, J. D., Kendall, S., Kazwala, R. R., …Matee, M. I. (2017). Isolation and Potential for Transmission of Mycobacterium bovis at Human–livestock–wildlife Interface of the Serengeti Ecosystem, Northern Tanzania. Transboundary and Emerging Diseases, 64(3), 815-825. https://doi.org/10.1111/tbed.12445

The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis (2016)
Journal Article
Ho, N. A. T., Dawes, S. S., Crowe, A. M., Casabon, I., Gao, C., Kendall, S. L., …Lott, J. S. (2016). The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis. Journal of Biological Chemistry, 291(14), 7256-7266. https://doi.org/10.1074/jbc.M115.707760

Cholesterol can be a major carbon source for Mycobacterium tuberculosis during infection, both at an early stage in the macrophage phagosome and later within the necrotic granuloma. KstR is a highly conserved TetR family transcriptional repressor tha... Read More about The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis.

Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis (2014)
Journal Article
Evangelopoulos, D., Gupta, A., Lack, N. A., Maitra, A., Ten Bokum, A. M. C., Kendall, S. L., …Bhakta, S. (2014). Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis. Tuberculosis, 94(6), 664-671. https://doi.org/10.1016/j.tube.2014.08.007

MSMEG_0307 is annotated as a transcriptional regulator belonging to the AraC protein family and is located adjacent to the arylamine N-acetyltransferase (nat) gene in Mycobacterium smegmatis, in a gene cluster, conserved in most environmental mycobac... Read More about Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis.

'One Health' infectious diseases surveillance in Tanzania: Are we all on board the same flight? (2012)
Journal Article
Mbugi, E. V., Kayunze, K. A., Katale, B. Z., Kendall, S., Good, L., Kibik, G. S., …Matee, M. I. (2012). 'One Health' infectious diseases surveillance in Tanzania: Are we all on board the same flight?. Onderstepoort Journal of Veterinary Research, 79(2), E1-7. https://doi.org/10.4102/ojvr.v79i2.500

Infectious diseases account for nearly 40% of the burden of human mortality and morbidity in low-income countries, of which 7% is attributable to zoonoses and 13% to recently emerging diseases from animals. One of the strategic approaches for effecti... Read More about 'One Health' infectious diseases surveillance in Tanzania: Are we all on board the same flight?.