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Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration (2014)
Journal Article
Kenward, H., Pelligand, L., & Elliott, J. (2014). Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration. Experimental Brain Research, 232(8), 2685-2697. https://doi.org/10.1007/s00221-014-3961-6

Cisplatin is a highly emetogenic cancer chemotherapy agent, which is often used to induce nausea and emesis in animal models. The cytotoxic properties of cisplatin also cause adverse events that negatively impact on animal welfare preventing repeated... Read More about Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration.

Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation (2014)
Journal Article
Pelligand, L., King, J. N., Hormazabal, V., Toutain, P. L., Elliott, J., & Lees, P. (2014). Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation. Journal of Veterinary Pharmacology and Therapeutics, 37(4), 354-366. https://doi.org/10.1111/jvp.12107

Robenacoxib and ketoprofen are acidic nonsteroidal anti‐inflammatory drugs (NSAIDs). Both are licensed for once daily administration in the cat, despite having short blood half‐lives. This study reports the pharmacokinetic/pharmacodynamic (PK/PD) mod... Read More about Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation.

Diagnosis of hyperthyroidism in cats with mild chronic kidney disease
Journal Article
Wakeling, J. M., Moore, K., Elliott, J., & Syme, H. M. Diagnosis of hyperthyroidism in cats with mild chronic kidney disease. Journal of Small Animal Practice, 49(6), 287-294. https://doi.org/10.1111/j.1748-5827.2008.00544.x

OBJECTIVES: In cats with concurrent hyperthyroidism and non-thyroidal illnesses such as chronic kidney disease, total thyroxine concentrations are often within the laboratory reference range (19 to 55 nmol/l). The objective of the study was to determ... Read More about Diagnosis of hyperthyroidism in cats with mild chronic kidney disease.

Subclinical hyperthyroidism in cats: A spontaneous model of subclinical toxic nodular goiter in humans?
Journal Article
Wakeling, J., Smith, K. C., Scase, T., Kirkby, R., Elliott, J., & Syme, H. M. Subclinical hyperthyroidism in cats: A spontaneous model of subclinical toxic nodular goiter in humans?. https://doi.org/10.1089/thy.2007.0225

Introduction and Objectives: Hyperthyroidism in cats, caused by nodular hyperplasia or adenomas, is clinically and histologically similar to toxic nodular goiter in humans. Subclinical hyperthyroidism in humans is defined as low thyrotropin (TSH) in... Read More about Subclinical hyperthyroidism in cats: A spontaneous model of subclinical toxic nodular goiter in humans?.