Skip to main content

Research Repository

Advanced Search

All Outputs (3013)

Epilepsy beyond seizures: a review of the impact of epilepsy and its comorbidities on health-related quality of life in dogs
Journal Article
Packer, R. M. A., & Volk, H. A. (in press). Epilepsy beyond seizures: a review of the impact of epilepsy and its comorbidities on health-related quality of life in dogs. Veterinary Record, 177(12), 306-315. https://doi.org/10.1136/vr.103360

Epilepsy is one of the most common chronic neurological conditions in the dog, estimated to affect 0.6 to 0.75 per cent of dogs. Owners of dogs with epilepsy have previously indicated that their dog's quality of life (QoL) is of greatest importance t... Read More about Epilepsy beyond seizures: a review of the impact of epilepsy and its comorbidities on health-related quality of life in dogs.

The Use of Recombinant Tissue Plasminogen Activator (rTPA) in The Treatment of Fibrinous Pleuropneumonia in Horses: 25 Cases (2007–2012)
Journal Article
Tomlinson, J. E., Byrne, E., Pusterla, N., Magdesian, K. G., Hilton, H. G., McGorum, B., …Johnson, A. L. (in press). The Use of Recombinant Tissue Plasminogen Activator (rTPA) in The Treatment of Fibrinous Pleuropneumonia in Horses: 25 Cases (2007–2012). Journal of Veterinary Internal Medicine, 29(5), 1403-1409. https://doi.org/10.1111/jvim.13594

International Veterinary Epilepsy Task Force consensus report on epilepsy definition, classification and terminology in companion animals
Journal Article
Berendt, M., Farquhar, R. G., Mandigers, P. J. J., Pakozdy, A., Bhatti, S. F. M., De Risio, L., …Volk, H. A. (in press). International Veterinary Epilepsy Task Force consensus report on epilepsy definition, classification and terminology in companion animals. BMC Veterinary Research, 11(182), https://doi.org/10.1186/s12917-015-0461-2

Dogs with epilepsy are among the commonest neurological patients in veterinary practice and therefore have historically attracted much attention with regard to definitions, clinical approach and management. A number of classification proposals for ca... Read More about International Veterinary Epilepsy Task Force consensus report on epilepsy definition, classification and terminology in companion animals.

International Veterinary Epilepsy Task Force consensus proposal: Medical treatment of canine epilepsy in Europe
Journal Article
Bhatti, S. F. M., De Risio, L., Munana, K., Penderis, J., Stein, V. M., Tipold, A., …Volk, H. A. (in press). International Veterinary Epilepsy Task Force consensus proposal: Medical treatment of canine epilepsy in Europe. BMC Veterinary Research, 11(176), https://doi.org/10.1186/s12917-015-0464-z

In Europe, the number of antiepileptic drugs (AEDs) licensed for dogs has grown considerably over the last years. Nevertheless, the same questions remain, which include, 1) when to start treatment, 2) which drug is best used initially, 3) which adjun... Read More about International Veterinary Epilepsy Task Force consensus proposal: Medical treatment of canine epilepsy in Europe.

International Veterinary Epilepsy Task Force Consensus Proposal: Diagnostic approach to epilepsy in dogs
Journal Article
De Risio, L., Bhatti, S. F. A., Munana, K., Penderis, J., Stein, V., Tipold, A., …Volk, H. A. (in press). International Veterinary Epilepsy Task Force Consensus Proposal: Diagnostic approach to epilepsy in dogs. BMC Veterinary Research, 11(148), https://doi.org/10.1186/s12917-015-0462-1

This article outlines the consensus proposal on diagnosis of epilepsy in dogs by the International Veterinary Epilepsy Task Force. The aim of this consensus proposal is to improve consistency in the diagnosis of epilepsy in the clinical and research... Read More about International Veterinary Epilepsy Task Force Consensus Proposal: Diagnostic approach to epilepsy in dogs.

International Veterinary Epilepsy Task Force's current understanding of idiopathic epilepsy of genetic or suspected genetic origin in purebred dogs
Journal Article
Hüelsmeyer, V., Fischer, A., Mandigers, P. J. J., De Risio, L., Berendt, M., Rusbridge, C., …Volk, H. A. (in press). International Veterinary Epilepsy Task Force's current understanding of idiopathic epilepsy of genetic or suspected genetic origin in purebred dogs. BMC Veterinary Research, 11, https://doi.org/10.1186/s12917-015-0463-0

Canine idiopathic epilepsy is a common neurological disease affecting both purebred and crossbred dogs. Various breed-specific cohort, epidemiological and genetic studies have been conducted to date, which all improved our knowledge and general under... Read More about International Veterinary Epilepsy Task Force's current understanding of idiopathic epilepsy of genetic or suspected genetic origin in purebred dogs.

International Veterinary Epilepsy Task Force recommendations for systematic sampling and processing of brains from epileptic dogs and cats
Journal Article
Matiasek, K., Pumarola Batlle, M., Rosati, M., Fernandez-Flores, F., Fischer, A., Wagner, E., …Volk, H. A. (in press). International Veterinary Epilepsy Task Force recommendations for systematic sampling and processing of brains from epileptic dogs and cats. BMC Veterinary Research, 11(216), https://doi.org/10.1186/s12917-015-0467-9

Traditionally, histological investigations of the epileptic brain are required to identify epileptogenic brain lesions, to evaluate the impact of seizure activity, to search for mechanisms of drug-resistance and to look for comorbidities. For many in... Read More about International Veterinary Epilepsy Task Force recommendations for systematic sampling and processing of brains from epileptic dogs and cats.

International Veterinary Epilepsy Task Force Consensus Proposal: Outcome of therapeutic interventions in canine and feline epilepsy
Journal Article
Potschka, H., Fischer, A., Loescher, W., Patterson, N., Bhatti, S. F. M., Berendt, M., …Volk, H. A. (in press). International Veterinary Epilepsy Task Force Consensus Proposal: Outcome of therapeutic interventions in canine and feline epilepsy. BMC Veterinary Research, 11(177), https://doi.org/10.1186/s12917-015-0465-y

Common criteria for the diagnosis of drug resistance and the assessment of outcome are needed urgently as a prerequisite for standardized evaluation and reporting of individual therapeutic responses in canine epilepsy. Thus, we provide a proposal for... Read More about International Veterinary Epilepsy Task Force Consensus Proposal: Outcome of therapeutic interventions in canine and feline epilepsy.

International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol
Journal Article
Rusbridge, C., Long, S., Jovanovik, J., Milne, M., Berendt, M., Bhatti, S. F. M., …Volk, H. A. (in press). International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol. BMC Veterinary Research, 11(194), https://doi.org/10.1186/s12917-015-0466-x

Epilepsy is one of the most common chronic neurological diseases in veterinary practice. Magnetic resonance imaging (MRI) is regarded as an important diagnostic test to reach the diagnosis of idiopathic epilepsy. However, given that the diagnosis req... Read More about International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol.

Monoacylated Cellular Prion Proteins Reduce Amyloid-beta-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage
Journal Article
West, E., Osborne, C., Nolan, W., & Bate, C. (in press). Monoacylated Cellular Prion Proteins Reduce Amyloid-beta-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage. Biology, 4(2), 367-82. https://doi.org/10.3390/biology4020367

Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by the accumulation of amyloid-β (Aβ) and the loss of synapses. Aggregation of the cellular prion protein (PrPC) by Aβ oligomers induced synapse damage in cultured neur... Read More about Monoacylated Cellular Prion Proteins Reduce Amyloid-beta-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage.

Management of incidentally detected heart murmurs in dogs and cats
Journal Article
Cote, E., Edwards, N. J., Ettinger, S. J., Fuentes, V. L., MacDonald, K. A., Scansen, B. A., …Abbott, J. A. (in press). Management of incidentally detected heart murmurs in dogs and cats. Journal of Veterinary Cardiology, 17(4), 245-261. https://doi.org/10.1016/j.jvc.2015.05.001

A dog or a cat has an incidentally detected heart murmur if the murmur is an unexpected discovery during a veterinary consultation that was not initially focused on the cardiovascular system. This document presents approaches for managing dogs and ca... Read More about Management of incidentally detected heart murmurs in dogs and cats.