All Outputs (6)

A functional eEF2K-eEF2 pathway in the NAc is critical for the expression of cocaine-induced psychomotor sensitisation and conditioned place preference (2022)
Journal Article
Beiser, T., Lisniansky, E., Weitz, M., Bingor, A., Grad, E., Rosenblum, K., Thornton, C., & Yaka, R. (2022). A functional eEF2K-eEF2 pathway in the NAc is critical for the expression of cocaine-induced psychomotor sensitisation and conditioned place preference. Translational Psychiatry, 12, Article 460. https://doi.org/10.1038/s41398-022-02232-1

Recent evidence links synaptic plasticity and mRNA translation, via the eukaryotic elongation factor 2 kinase (eEF2K) and its only known substrate, eEF2. However, the involvement of the eEF2 pathway in cocaine-induced neuroadaptations and cocaine-ind... Read More about A functional eEF2K-eEF2 pathway in the NAc is critical for the expression of cocaine-induced psychomotor sensitisation and conditioned place preference.

Rational determination of cefazolin dosage regimen in horses based on pharmacokinetics/pharmacodynamics principles and Monte Carlo simulations (2022)
Journal Article
Kuroda, T., Minamijima, Y., Mita, H., Tamura, N., Fukuda, K., Kuwano, A., Toutain, P., & Sato, F. (2022). Rational determination of cefazolin dosage regimen in horses based on pharmacokinetics/pharmacodynamics principles and Monte Carlo simulations. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.13099

A pharmacokinetics/pharmacodynamics (PK/PD) approach was used to determine
the best empirical dosage regimen of cefazolin (CEZ) after intramuscular (IM) administration
of CEZ in horses. Seven horses received a single IM or intravenous (IV) administ... Read More about Rational determination of cefazolin dosage regimen in horses based on pharmacokinetics/pharmacodynamics principles and Monte Carlo simulations.

Bats actively modulate membrane compliance to control camber and reduce drag (2022)
Journal Article
Cheney, J., Rehm, J., Swartz, S., & Breuer, K. (in press). Bats actively modulate membrane compliance to control camber and reduce drag. Journal of Experimental Biology, https://doi.org/10.1242/jeb.243974

Bat wing skin is exceptionally compliant and cambers significantly during flight. Plagiopatagiales proprii, arrays of small muscles embedded in the armwing membrane, are activated during flight and are hypothesized to modulate membrane tension. We ex... Read More about Bats actively modulate membrane compliance to control camber and reduce drag.

New concepts in phosphorus homeostasis and its impact on renal health with particular reference to the cat (2022)
Journal Article
Elliott, J., & Geddes, R. F. (2022). New concepts in phosphorus homeostasis and its impact on renal health with particular reference to the cat. The Veterinary Journal, 283-284, Article 105842. https://doi.org/10.1016/j.tvjl.2022.105842

New discoveries relating to phosphorus homeostasis include the hormones fibroblast growth factor-23 and klotho produced by bone and kidney. These hormones, together with novel understanding of how calcium and phosphate ions are carried in colloidal f... Read More about New concepts in phosphorus homeostasis and its impact on renal health with particular reference to the cat.

Mitochondrial Dynamics in the Neonatal Brain -a potential target following injury? (2022)
Journal Article
Jones, A., & Thornton, C. (2022). Mitochondrial Dynamics in the Neonatal Brain -a potential target following injury?. Bioscience Reports, https://doi.org/10.1042/BSR20211696

The impact of birth asphyxia and its sequelae, hypoxic-ischaemic brain injury, is long lasting and significant, both for the infant and for their family. Treatment options are limited to therapeutic hypothermia, which is not universally successful an... Read More about Mitochondrial Dynamics in the Neonatal Brain -a potential target following injury?.

Virtual manipulation of tail postures of a gliding barn owl (Tyto alba) demonstrates drag minimisation when gliding (2022)
Journal Article
Song, J., Cheney, J., Bomphrey, R., & Usherwood, J. (2023). Virtual manipulation of tail postures of a gliding barn owl (Tyto alba) demonstrates drag minimisation when gliding. Journal of the Royal Society, Interface, https://doi.org/10.1098/rsif.2021.0710

Aerodynamic functions of the avian tail have been studied previously using observations of bird flight, physical models in wind tunnels, theoretical modelling, and flow visualization. However, none of these approaches has provided rigorous, quantitat... Read More about Virtual manipulation of tail postures of a gliding barn owl (Tyto alba) demonstrates drag minimisation when gliding.