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Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts
Journal Article
Shah, D., Takahashi-Makise, N., Cooney, J. D., Liangao, L., Schultz, I. J., Pierce, E. L., …Paw, B. H. (in press). Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts. Nature, 491(7425), 608-612. https://doi.org/10.1038/nature11536

Defects in the availability of haem substrates or the catalytic activity of the terminal enzyme in haem biosynthesis, ferrochelatase (Fech), impair haem synthesis and thus cause human congenital anaemias1,2. The interdependent functions of regulators... Read More about Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts.

Preventing phosphorylation of dystroglycan ameliorates the dystrophic phenotype in mdx mouse
Journal Article
Miller, G., Moore, C. J., Terry, R. L., La Riviere, T., Mitchell, A., Piggott, R., …Winder, S. J. (in press). Preventing phosphorylation of dystroglycan ameliorates the dystrophic phenotype in mdx mouse. Human Molecular Genetics, 21(20), 4508-4520. https://doi.org/10.1093/hmg/dds293

Loss of dystrophin protein due to mutations in the DMD gene causes Duchenne muscular dystrophy. Dystrophin loss also leads to the loss of the dystrophin glycoprotein complex (DGC) from the sarcolemma which contributes to the dystrophic phenotype. Tyr... Read More about Preventing phosphorylation of dystroglycan ameliorates the dystrophic phenotype in mdx mouse.

IFPA Meeting 2011 workshop report III: Placental immunology; epigenetic and microRNA-dependent gene regulation; comparative placentation; trophoblast differentiation; stem cells
Journal Article
Ackerman, W. E., Bulmer, J. N., Carter, A. M., Chaillet, J. R., Chamley, L., Chen, C. P., …Lash, G. E. IFPA Meeting 2011 workshop report III: Placental immunology; epigenetic and microRNA-dependent gene regulation; comparative placentation; trophoblast differentiation; stem cells. Placenta, 33, S15-S22. https://doi.org/10.1016/j.placenta.2011.11.022