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PPAR alpha-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status
Journal Article
Caton, P. W., Holness, M. J., Bishop-Bailey, D., & Sugden, M. C. (in press). PPAR alpha-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status. Biochemical Journal, 437(3), 521-530. https://doi.org/10.1042/BJ20110702

LXR (liver X receptor) and PPARα (peroxisome-proliferator-activated receptor α) are nuclear receptors that control the expression of genes involved in glucose and lipid homoeostasis. Using wild-type and PPARα-null mice fed on an LXR-agonist-supplemen... Read More about PPAR alpha-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status.

High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway
Journal Article
Bravo, E., Palleschi, S., Aspichueta, P., Buque, X., Rossi, B., Cano, A., …Botham, K. M. High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway. Lipids in Health and Disease, 10(60), https://doi.org/10.1186/1476-511X-10-60