Behavioural changes in dogs with idiopathic epilepsy
(2019)
Journal Article
Watson, F., Packer, R. M. A., Rusbridge, C., & Volk, H. A. (2019). Behavioural changes in dogs with idiopathic epilepsy. Veterinary Record, https://doi.org/10.1136/vr.105222
All Outputs (71)
Comparison of signalment and computed tomography findings in French Bulldogs, Pugs, and English Bulldogs with and without clinical signs associated with thoracic hemivertebra (2019)
Journal Article
De Decker, S., Packer, R. M. A., Cappello, R., Harcourt-Brown, T. R., Rohdin, C., Gomes, S. A., Bergknut, N., Shaw, T. A., Lowrie, M., & Gutierrez-Quintana, R. (2019). Comparison of signalment and computed tomography findings in French Bulldogs, Pugs, and English Bulldogs with and without clinical signs associated with thoracic hemivertebra. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15556
Great expectations, inconvenient truths, and the paradoxes of the dog-owner relationship for owners of brachycephalic dogs (2019)
Journal Article
Packer, R. M. A., O'Neill, D. G., Fletcher, F., & Farnworth, M. J. (2019). Great expectations, inconvenient truths, and the paradoxes of the dog-owner relationship for owners of brachycephalic dogs. PLoS ONE, https://doi.org/10.1371/journal.pone.0219918Popularity of brachycephalic (flat-faced) dog breeds is increasing internationally despite well-documented intrinsic health and welfare problems associated with their conformation. Given this apparent paradox, greater understanding of the expectation... Read More about Great expectations, inconvenient truths, and the paradoxes of the dog-owner relationship for owners of brachycephalic dogs.
Disorders of Bulldogs under primary veterinary care in the UK in 2013 (2019)
Journal Article
O'Neill, D. G., Skipper, A. M., Kadhim, J., Church, D. B., Brodbelt, D. C., & Packer, R. M. A. (2019). Disorders of Bulldogs under primary veterinary care in the UK in 2013. PLoS ONE, 14(6), e0217928. https://doi.org/10.1371/journal.pone.0217928The Bulldog is a popular companion breed in the UK despite widely reported disease predispositions. This study aimed to characterise the demography, mortality and common disorders of Bulldogs under veterinary care in the UK during 2013. VetCompass co... Read More about Disorders of Bulldogs under primary veterinary care in the UK in 2013.
A double-blinded randomised dietary supplement crossover trial design to investigate the short-term influence of medium chain fatty acid (MCT) supplement on canine idiopathic epilepsy: study protocol (2019)
Journal Article
Berk, B. A., Packer, R. M. A., Law, T. H., Wessmann, A., Bathen-Nöthen, A., Jokinen, T. S., Knebel, A., Tipold, A., Pelligand, L., & Volk, H. A. (2019). A double-blinded randomised dietary supplement crossover trial design to investigate the short-term influence of medium chain fatty acid (MCT) supplement on canine idiopathic epilepsy: study protocol. BMC Veterinary Research, 15(181), https://doi.org/10.1186/s12917-019-1915-8
What can we learn from the hair of the dog? Complex effects of endogenous and exogenous stressors on canine hair cortisol (2019)
Journal Article
Packer, R. M. A., Davies, A. M., Volk, H. A., Puckett, H. L., Hobbs, S. L., & Fowkes, R. C. (2019). What can we learn from the hair of the dog? Complex effects of endogenous and exogenous stressors on canine hair cortisol. PLoS ONE, 14(5), e0216000. https://doi.org/10.1371/journal.pone.0216000Hair is an emerging biological matrix in which to measure chronic HPA axis activity, offering a longer term view into an animal’s life. We explored effects of exogenous (e.g. lifestyle, medications, social environment) and endogenous (e.g. disease, b... Read More about What can we learn from the hair of the dog? Complex effects of endogenous and exogenous stressors on canine hair cortisol.
Gait analysis in French bulldogs with and without vertebral kyphosis (2019)
Journal Article
Wyatt, S. E., Lafuente, M. P., Ter Haar, G., Packer, R. M. A., Smith, H., & De Decker, S. (2019). Gait analysis in French bulldogs with and without vertebral kyphosis. https://doi.org/10.1016/j.tvjl.2018.12.008The study objective was to compare temporal-spatial and kinetic gait variables in neurologically normal French bulldogs with and without vertebral kyphosis. French bulldogs presented to a dedicated brachycephalic clinic were prospectively enrolled. A... Read More about Gait analysis in French bulldogs with and without vertebral kyphosis.
Health-related quality of life following surgical attenuation of congenital portosystemic shunts versus a healthy control population of dogs (2019)
Journal Article
Bristow, P. C., Lipscomb, V. J., Kummeling, A., Packer, R. M. A., Gerrits, H., Homan, K., Ortiz, V., Newson, K., & Tivers, M. S. (2019). Health-related quality of life following surgical attenuation of congenital portosystemic shunts versus a healthy control population of dogs. Journal of Small Animal Practice, 60(1), 21-26. https://doi.org/10.1111/jsap.12927
Investigating owner use of dietary supplements in dogs with idiopathic epilepsy (2018)
Journal Article
Berk, B. A., Packer, R. M. A., Law, T. H., & Volk, H. A. (2018). Investigating owner use of dietary supplements in dogs with idiopathic epilepsy. Research in Veterinary Science, 119, 276-284. https://doi.org/10.1016/j.rvsc.2018.07.004Epilepsy is the most common chronic neurological disorder in dogs. Some diets have been shown to have a positive impact upon the seizure activity in dogs with idiopathic epilepsy (IE), while other diets and dietary supplements (DS), although marketed... Read More about Investigating owner use of dietary supplements in dogs with idiopathic epilepsy.
A review of treatment options for behavioural manifestations of clinical anxiety as a comorbidity in dogs with idiopathic epilepsy (2018)
Journal Article
Watson, F., Rusbridge, C., Packer, R. M. A., Casey, R. A., Heath, S., & Volk, H. A. (2018). A review of treatment options for behavioural manifestations of clinical anxiety as a comorbidity in dogs with idiopathic epilepsy. https://doi.org/10.1016/j.tvjl.2018.06.001Psychiatric comorbidities affect a large percentage of people with epilepsy and have a detrimental impact on their quality of life. Recently, behavioural comorbidities, with similar characteristics to human psychiatric diseases, have been identified... Read More about A review of treatment options for behavioural manifestations of clinical anxiety as a comorbidity in dogs with idiopathic epilepsy.
Demography and disorders of the French Bulldog population under primary veterinary care in the UK in 2013 (2018)
Journal Article
O'Neill, D. G., Baral, L., Church, D. B., Brodbelt, D. C., & Packer, R. M. A. (2018). Demography and disorders of the French Bulldog population under primary veterinary care in the UK in 2013. Canine Genetics and Epidemiology, 5(3), https://doi.org/10.1186/s40575-018-0057-9
Preliminary assessment of cognitive impairments in canine idiopathic epilepsy (2018)
Journal Article
Winter, J., Packer, R. M. A., & Volk, H. A. (2018). Preliminary assessment of cognitive impairments in canine idiopathic epilepsy. Veterinary Record, https://doi.org/10.1136/vr.104603In humans, epilepsy can induce or accelerate cognitive impairment (CI). There is emerging evidence of CI in dogs with idiopathic epilepsy (IE) from recent epidemiological studies. The aim of our study was to assess CI in dogs with IE using two tests... Read More about Preliminary assessment of cognitive impairments in canine idiopathic epilepsy.
Cognitive dysfunction in naturally occurring canine idiopathic epilepsy (2018)
Journal Article
Packer, R. M. A., McGreevy, P. D., Salvin, H. E., Valenzuela, M. J., Chaplin, C. M., & Volk, H. A. (2018). Cognitive dysfunction in naturally occurring canine idiopathic epilepsy. PLoS ONE, 13(2), e0192182. https://doi.org/10.1371/journal.pone.0192182Globally, epilepsy is a common serious brain disorder. In addition to seizure activity, epilepsy is associated with cognitive impairments including static cognitive impairments present at onset, progressive seizure-induced impairments and co-morbid d... Read More about Cognitive dysfunction in naturally occurring canine idiopathic epilepsy.
Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs (2018)
Journal Article
De Souza, M. C. C. M. I., Ryan, R., Ter Haar, G., Packer, R. M. A., Volk, H. A., & De Decker, S. (2018). Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs. BMC Veterinary Research, 14, 5. https://doi.org/10.1186/s12917-017-1316-9Although thoracic vertebral malformations with kyphosis and scoliosis are often considered incidental findings on diagnostic imaging studies of screw-tailed brachycephalic breeds, they have been suggested to interfere with spinal biomechanics and int... Read More about Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs.
Negative effects of epilepsy and antiepileptic drugs on the trainability of dogs with naturally occurring idiopathic epilepsy (2018)
Journal Article
Packer, R. M. A., McGreevy, P. D., Pergande, A., & Volk, H. A. (2018). Negative effects of epilepsy and antiepileptic drugs on the trainability of dogs with naturally occurring idiopathic epilepsy. Applied Animal Behaviour Science, 200, 106-113. https://doi.org/10.1016/j.applanim.2017.11.008Epilepsy and anti-epileptic drug (AED) treatment have been found to induce or exacerbate underlying cognitive impairments in people, affecting learning ability, attention and memory. Idiopathic epilepsy (IE) is the most common chronic neurological co... Read More about Negative effects of epilepsy and antiepileptic drugs on the trainability of dogs with naturally occurring idiopathic epilepsy.
Survival in feline epilepsy: the long and short of it (2017)
Journal Article
Packer, R. M. A. (2017). Survival in feline epilepsy: the long and short of it. Veterinary Record, 181(18), 477-478
Physiological reactivity to spontaneously occurring seizure activity in dogs with epilepsy and their carers (2017)
Journal Article
Packer, R. M. A., Volk, H. A., & Fowkes, R. C. (2017). Physiological reactivity to spontaneously occurring seizure activity in dogs with epilepsy and their carers. Physiology and Behavior, 177, 27-33. https://doi.org/10.1016/j.physbeh.2017.04.008There is a complex bidirectional relationship between stress and epilepsy. Stressful stimuli and subsequent cortisol release act as a trigger for seizure activity in some individuals with epilepsy, and seizure activity itself may act as a stressor to... Read More about Physiological reactivity to spontaneously occurring seizure activity in dogs with epilepsy and their carers.
Clinical reasoning in feline epilepsy: Which combination of clinical information is useful? (2017)
Journal Article
Stanciu, G. D., Packer, R. M. A., Pakozdy, A., Solcan, G., & Volk, H. A. (2017). Clinical reasoning in feline epilepsy: Which combination of clinical information is useful?. https://doi.org/10.1016/j.tvjl.2017.04.001We sought to identify the association between clinical risk factors and the diagnosis of idiopathic epilepsy (IE) or structural epilepsy (SE) in cats, using statistical models to identify combinations of discrete parameters from the patient signalmen... Read More about Clinical reasoning in feline epilepsy: Which combination of clinical information is useful?.
Purchasing popular purebreds: Investigating the influence of breed-type on the pre-purchase attitudes and behaviour of dog owners (2017)
Journal Article
Packer, R. M. A., Murphy, D., & Farnworth, M. J. (2017). Purchasing popular purebreds: Investigating the influence of breed-type on the pre-purchase attitudes and behaviour of dog owners. https://doi.org/10.7120/09627286.26.2.191
Owner perception of focal seizures in canine epilepsy (2017)
Journal Article
Packer, R. M. A., Lucas, R., & Volk, H. A. (2017). Owner perception of focal seizures in canine epilepsy. Veterinary Record, 180(6), 150. https://doi.org/10.1136/vr.104099