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All Outputs (91)

Comparison of gabapentin versus topiramate on clinically affected dogs with Chiari-like malformation and syringomyelia (2015)
Journal Article
Plessas, I. N., Volk, H. A., Rusbridge, C., Vanhaesebrouck, A. E., & Jeffery, N. D. (2015). Comparison of gabapentin versus topiramate on clinically affected dogs with Chiari-like malformation and syringomyelia. Veterinary Record, 177(11), 288-288. https://doi.org/10.1136/vr.103234

To date there is no evidence-based data for efficacious treatment of neuropathic pain in dogs with Chiari-like malformation (CM) and syringomyelia (SM). The objective of this prospective cross-over study was to compare the effect of gabapentin versus... Read More about Comparison of gabapentin versus topiramate on clinically affected dogs with Chiari-like malformation and syringomyelia.

Familial cardiomyopathy in Norwegian Forest cats (2015)
Journal Article
Maerz, I., Wilkie, L. J., Harrington, N., Payne, J. R., Muzzi, R. A. L., Haggstrom, J., Smith, K. C., & Fuentes, V. L. (2015). Familial cardiomyopathy in Norwegian Forest cats. Journal of Feline Medicine and Surgery, 17(8), 681-91. https://doi.org/10.1177/1098612X14553686

Norwegian Forest cats (NFCs) are often listed as a breed predisposed to cardiomyopathy, but the characteristics of cardiomyopathy in this breed have not been described. The aim of this preliminary study was to report the features of NFC cardiomyopath... Read More about Familial cardiomyopathy in Norwegian Forest cats.

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse (2015)
Journal Article
Godfrey, C., Muses, S., McClorey, G., Wells, K. E., Coursindel, T., Terry, R. L., Betts, C., Hammond, S., O'Donovan, L., Hildyard, J. C. W., El Andaloussi, S., Gait, M. J., Wood, M. J., & Wells, D. J. (2015). How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse. Human Molecular Genetics, 24(15), 4225-4237. https://doi.org/10.1093/hmg/ddv155

Clinical reasoning in canine spinal disease: what combination of clinical information is useful? (2015)
Journal Article
Cardy, T. J. A., De Decker, S., Kenny, P. J., & Volk, H. A. (2015). Clinical reasoning in canine spinal disease: what combination of clinical information is useful?. Veterinary Record, 177(7), https://doi.org/10.1136/vr.102988

Spinal disease in dogs is commonly encountered in veterinary practice. Numerous diseases may cause similar clinical signs and presenting histories. The study objective was to use statistical models to identify combinations of discrete parameters from... Read More about Clinical reasoning in canine spinal disease: what combination of clinical information is useful?.

HACD1, a regulator of membrane composition and fluidity, promotes myoblast fusion and skeletal muscle growth (2015)
Journal Article
Blondelle, J., Ohno, Y., Gache, V., Guyot, S., Storck, S., Blanchard-Gutton, N., Barthelemy, I., Walmsley, G. L., Rahier, A., Gadin, S., Maurer, M., Guillaud, L., Prola, A., Ferry, A., Aubin-Houzelstein, G., Demarquoy, J., Relaix, F., Piercy, R. J., Blot, S., Kihara, A., …Pilot-Storck, F. (2015). HACD1, a regulator of membrane composition and fluidity, promotes myoblast fusion and skeletal muscle growth. Journal of Molecular Cell Biology, 7(5), 429-440. https://doi.org/10.1093/jmcb/mjv049

The reduced diameter of skeletal myofibres is a hallmark of several congenital myopathies, yet the underlying cellular and molecular mechanisms remain elusive. In this study, we investigate the role of HACD1/PTPLA, which is involved in the elongation... Read More about HACD1, a regulator of membrane composition and fluidity, promotes myoblast fusion and skeletal muscle growth.

Lipopolysaccharide and toll-like receptor 4 in dogs with congenital portosystemic shunts (2015)
Journal Article
Tivers, M. S., Lipscomb, V. J., Smith, K. C., Wheeler-Jones, C. P. D., & House, A. K. (2015). Lipopolysaccharide and toll-like receptor 4 in dogs with congenital portosystemic shunts. https://doi.org/10.1016/j.tvjl.2015.07.006

Surgical attenuation of a congenital portosystemic shunt (CPSS) results in increased portal vein perfusion, liver growth and clinical improvement. Portal lipopolysaccharide (LPS) is implicated in liver regeneration via toll-like receptor (TLR) 4 medi... Read More about Lipopolysaccharide and toll-like receptor 4 in dogs with congenital portosystemic shunts.

Understanding hind limb lameness signs in horses using simple rigid body mechanics (2015)
Journal Article
Starke, S. D., May, S. A., & Pfau, T. (2015). Understanding hind limb lameness signs in horses using simple rigid body mechanics. Journal of Biomechanics, 48(12), 3323-3331. https://doi.org/10.1016/j.jbiomech.2015.06.019

Hind limb lameness detection in horses relies on the identification of movement asymmetry which can be based on multiple pelvic landmarks. This study explains the poorly understood relationship between hind limb lameness pointers, related to the tube... Read More about Understanding hind limb lameness signs in horses using simple rigid body mechanics.

Cervical masses in dogs and cats 1. Investigation and management (2015)
Journal Article
Bristow, P. C. (2015). Cervical masses in dogs and cats 1. Investigation and management. Companion Animal, 37(6), https://doi.org/10.1136/inp.h1316

Abnormalities in the cervical region can be challenging to investigate and manage; however, the area is a common location for disease processes in dogs and cats. The anatomy of this region can make investigations and treatment difficult and a thoroug... Read More about Cervical masses in dogs and cats 1. Investigation and management.