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Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity (2015)
Journal Article
Oguejiofor, C. F., Cheng, Z. R., Abudureyimu, A., Fouladi-Nashta, A. A., & Wathes, D. C. (2015). Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity. Biology of Reproduction, 93(4), https://doi.org/10.1095/biolreprod.115.128868

The dysregulation of endometrial immune response to bacterial lipopolysaccharide (LPS) has been implicated in uterine disease and infertility in the postpartum dairy cow, although the mechanisms are not clear. Here, we investigated whole-transcriptom... Read More about Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity.

Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide (2015)
Journal Article
Oguejiofor, C. F., Cheng, Z. R., Abudureyimu, A., Anstaett, O. L., Brownlie, J., Fouladi-Nashta, A. A., & Wathes, D. C. (2015). Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide. Biology of Reproduction, 93(4), https://doi.org/10.1095/biolreprod.115.128876

Infection with noncytopathic bovine viral diarrhea virus (ncpBVDV) is associated with uterine disease and infertility. This study investigated the influence of ncpBVDV on immune functions of the bovine endometrium by testing the response to bacterial... Read More about Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide.

Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow (2015)
Journal Article
Chen, X., Cheng, Z. R., Zhang, S., Werling, D., & Wathes, D. C. (2015). Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow. Open Journal of Animal Sciences, 5(4), 358-393. https://doi.org/10.4236/ojas.2015.54040

Mastitis is a costly disease which hampers the dairy industry. Inflammation of the mammary gland is commonly caused by bacterial infection, mainly Escherichia coli, Streptococcus uberis and Staphylococcus aureus. As more bacteria become multi-drug re... Read More about Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow.

bak deletion stimulates gastric epithelial proliferation and enhances Helicobacter felis-induced gastric atrophy and dysplasia in mice (2015)
Journal Article
Duckworth, C. A., Abuderman, A. A., Burkitt, M. D., Williams, J. M., O'Reilly, L. A., & Pritchard, D. M. (2015). bak deletion stimulates gastric epithelial proliferation and enhances Helicobacter felis-induced gastric atrophy and dysplasia in mice. https://doi.org/10.1152/ajpgi.00404.2014

Helicobacter infection causes a chronic superficial gastritis that in some cases progresses via atrophic gastritis to adenocarcinoma. Proapoptotic bak has been shown to regulate radiation-induced apoptosis in the stomach and colon and also susceptibi... Read More about bak deletion stimulates gastric epithelial proliferation and enhances Helicobacter felis-induced gastric atrophy and dysplasia in mice.

Population, genetic, and antigenic diversity of the apicomplexan Eimeria tenella and their relevance to vaccine development (2015)
Journal Article
Blake, D. P., Clark, E. L., Macdonald, S. E., Thenmozhi, V., Kundu, K., Garg, R., …Tomley, F. M. (2015). Population, genetic, and antigenic diversity of the apicomplexan Eimeria tenella and their relevance to vaccine development. https://doi.org/10.1073/pnas.1506468112

The phylum Apicomplexa includes serious pathogens of humans and animals. Understanding the distribution and population structure of these protozoan parasites is of fundamental importance to explain disease epidemiology and develop sustainable control... Read More about Population, genetic, and antigenic diversity of the apicomplexan Eimeria tenella and their relevance to vaccine development.

Relationships between Circulating Urea Concentrations and Endometrial Function in Postpartum Dairy Cows (2015)
Journal Article
Cheng, Z. R., Oguejiofor, C. F., Swangchan-Uthai, T., Carr, S., & Wathes, D. C. (2015). Relationships between Circulating Urea Concentrations and Endometrial Function in Postpartum Dairy Cows. Animals, 5(3), 748-773. https://doi.org/10.3390/ani5030382

Both high and low circulating urea concentrations, a product of protein metabolism, are associated with decreased fertility in dairy cows through poorly defined mechanisms. The rate of involution and the endometrial ability to mount an adequate innat... Read More about Relationships between Circulating Urea Concentrations and Endometrial Function in Postpartum Dairy Cows.

Outbreak of encephalitic listeriosis in red-legged partridges (Alectoris rufa) (2015)
Journal Article
Jeckel, S. J., Wood, A., Grant, K., Amar, C., King, S. A., Whatmore, A. M., …Welchman, D. D. B. (2015). Outbreak of encephalitic listeriosis in red-legged partridges (Alectoris rufa). Avian Pathology, 44(4), 269-277. https://doi.org/10.1080/03079457.2015.1042427

An outbreak of neurological disease was investigated in red-legged partridges between 8 and 28 days of age. Clinical signs included torticollis, head tilt and incoordination and over an initial eight day period approximately 30–40 fatalities occurred... Read More about Outbreak of encephalitic listeriosis in red-legged partridges (Alectoris rufa).

Global trends in infectious diseases at the wildlife–livestock interface (2015)
Journal Article
Wiethoelter, A. K., Beltran-Alcrudo, D., Kock, R. A., & Mor, S. M. (2015). Global trends in infectious diseases at the wildlife–livestock interface. https://doi.org/10.1073/pnas.1422741112

The role and significance of wildlife–livestock interfaces in disease ecology has largely been neglected, despite recent interest in animals as origins of emerging diseases in humans. Scoping review methods were applied to objectively assess the rela... Read More about Global trends in infectious diseases at the wildlife–livestock interface.

Familial cardiomyopathy in Norwegian Forest cats (2015)
Journal Article
Maerz, I., Wilkie, L. J., Harrington, N., Payne, J. R., Muzzi, R. A. L., Haggstrom, J., …Fuentes, V. L. (2015). Familial cardiomyopathy in Norwegian Forest cats. Journal of Feline Medicine and Surgery, 17(8), 681-91. https://doi.org/10.1177/1098612X14553686

Norwegian Forest cats (NFCs) are often listed as a breed predisposed to cardiomyopathy, but the characteristics of cardiomyopathy in this breed have not been described. The aim of this preliminary study was to report the features of NFC cardiomyopath... Read More about Familial cardiomyopathy in Norwegian Forest cats.

Influenza A virus evolution and spatio-temporal dynamics in Eurasian wild birds: a phylogenetic and phylogeographical study of whole-genome sequence data (2015)
Journal Article
Lewis, N. S., Verhagen, J. H., Javakhishvili, Z., Russell, C. A., Lexmond, P., Westgeest, K. B., …De Graaf, M. (2015). Influenza A virus evolution and spatio-temporal dynamics in Eurasian wild birds: a phylogenetic and phylogeographical study of whole-genome sequence data. Journal of General Virology, 96(8), 2050-60. https://doi.org/10.1099/vir.0.000155

Low pathogenic avian influenza A viruses (IAVs) have a natural host reservoir in wild waterbirds and the potential to spread to other host species. Here, we investigated the evolutionary, spatial and temporal dynamics of avian IAVs in Eurasian wild b... Read More about Influenza A virus evolution and spatio-temporal dynamics in Eurasian wild birds: a phylogenetic and phylogeographical study of whole-genome sequence data.

Effect of oleic acid supplementation on prostaglandin production in maternal endometrial and fetal allantochorion cells isolated from late gestation ewes (2015)
Journal Article
Cheng, Z. R., Abayasekara, D. R. E., Elmes, M., Kirkup, S. E., & Wathes, D. C. (2015). Effect of oleic acid supplementation on prostaglandin production in maternal endometrial and fetal allantochorion cells isolated from late gestation ewes. Placenta, 36(9), 1011-1017. https://doi.org/10.1016/j.placenta.2015.07.128

Elevated circulating non-esterified fatty acids including oleic acid (OA) are associated with many pregnancy related complications. Prostaglandins (PGs) play crucial roles during parturition. We investigated the effect of OA supplementation on PG pro... Read More about Effect of oleic acid supplementation on prostaglandin production in maternal endometrial and fetal allantochorion cells isolated from late gestation ewes.

Adolescents care but don't feel responsible for farm animal welfare (2015)
Journal Article
Jamieson, J., Reiss, M. J., Allen, D., Asher, L., Parker, M. O., Wathes, C. M., & Abeyesinghe, S. M. (2015). Adolescents care but don't feel responsible for farm animal welfare. Society and Animals, 23(3), 269-297. https://doi.org/10.1163/15685306-12341283

Adolescents are the next generation of consumers with the potential to raise standards of farm animal welfare—to theirsatisfaction—if their preferences and concerns are translated into accurate market drivers and signals. There are no published data... Read More about Adolescents care but don't feel responsible for farm animal welfare.

Lipopolysaccharide and toll-like receptor 4 in dogs with congenital portosystemic shunts (2015)
Journal Article
Tivers, M. S., Lipscomb, V. J., Smith, K. C., Wheeler-Jones, C. P. D., & House, A. K. (2015). Lipopolysaccharide and toll-like receptor 4 in dogs with congenital portosystemic shunts. https://doi.org/10.1016/j.tvjl.2015.07.006

Surgical attenuation of a congenital portosystemic shunt (CPSS) results in increased portal vein perfusion, liver growth and clinical improvement. Portal lipopolysaccharide (LPS) is implicated in liver regeneration via toll-like receptor (TLR) 4 medi... Read More about Lipopolysaccharide and toll-like receptor 4 in dogs with congenital portosystemic shunts.