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The cat as a naturally occurring model of renal interstitial fibrosis: Characterisation of primary feline proximal tubular epithelial cells and comparative pro-fibrotic effects of TGF-ß1 (2018)
Journal Article
Lawson, J. S., Liu, H., Syme, H. M., Purcell, R., Wheeler-Jones, C. P. D., & Elliott, J. (2018). The cat as a naturally occurring model of renal interstitial fibrosis: Characterisation of primary feline proximal tubular epithelial cells and comparative pro-fibrotic effects of TGF-ß1. PLoS ONE, 13(8), e0202577. https://doi.org/10.1371/journal.pone.0202577

Chronic kidney disease (CKD) is common in both geriatric cats and aging humans, and is pathologically characterised by chronic tubulointerstitial inflammation and fibrosis in both species. Cats with CKD may represent a spontaneously occurring, non-ro... Read More about The cat as a naturally occurring model of renal interstitial fibrosis: Characterisation of primary feline proximal tubular epithelial cells and comparative pro-fibrotic effects of TGF-ß1.

Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1 (2018)
Journal Article
Lawson, J. S., Syme, H. M., Wheeler-Jones, C. P. D., & Elliott, J. (2018). Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1. BMC Veterinary Research, 14, 76. https://doi.org/10.1186/s12917-018-1387-2

Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matrix in renal fibrosis... Read More about Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1.