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All Outputs (11)

Survival after diagnosis of hypertension in cats attending primary care practice in the UK (2018)
Journal Article
Chang, Y. M., Brodbelt, D. C., Elliott, J., & Conroy, M. C. (2018). Survival after diagnosis of hypertension in cats attending primary care practice in the UK. Journal of Veterinary Internal Medicine, 32(6), 1846-1855. https://doi.org/10.1111/jvim.15307

Background: Hypertension is common in older cats. There is limited evidence for predictors of survival after diagnosis. Hypothesis/Objectives: Investigate blood pressure assessment (BPA) and hypertension diagnosis in cats attending UK primary care... Read More about Survival after diagnosis of hypertension in cats attending primary care practice in the UK.

The cat as a naturally occurring model of renal interstitial fibrosis: Characterisation of primary feline proximal tubular epithelial cells and comparative pro-fibrotic effects of TGF-ß1 (2018)
Journal Article
Lawson, J. S., Liu, H., Syme, H. M., Purcell, R., Wheeler-Jones, C. P. D., & Elliott, J. (2018). The cat as a naturally occurring model of renal interstitial fibrosis: Characterisation of primary feline proximal tubular epithelial cells and comparative pro-fibrotic effects of TGF-ß1. PLoS ONE, 13(8), e0202577. https://doi.org/10.1371/journal.pone.0202577

Chronic kidney disease (CKD) is common in both geriatric cats and aging humans, and is pathologically characterised by chronic tubulointerstitial inflammation and fibrosis in both species. Cats with CKD may represent a spontaneously occurring, non-ro... Read More about The cat as a naturally occurring model of renal interstitial fibrosis: Characterisation of primary feline proximal tubular epithelial cells and comparative pro-fibrotic effects of TGF-ß1.

Cell specific microvesicles vary with season and disease predisposition in healthy and previously laminitic ponies (2018)
Journal Article
Finding, E. J. T., Lawson, C., Elliott, J., Harris, P. A., & Menzies-Gow, N. J. (2018). Cell specific microvesicles vary with season and disease predisposition in healthy and previously laminitic ponies. Veterinary Immunology and Immunopathology, https://doi.org/10.1016/j.vetimm.2018.06.001

Microvesicles are small (up to 1 μm) vesicles found in plasma and other bodily fluids. They are recognised as part of the normal system of inter-cellular communication but altered numbers are also used as biomarkers of disease. Microvesicles have not... Read More about Cell specific microvesicles vary with season and disease predisposition in healthy and previously laminitic ponies.

Seasonal and dietary influences on adipose tissue and systemic gene expression in control and previously laminitic ponies (2018)
Journal Article
Timpson, A., De Mestre, A. M., Elliott, J., Harris, P. A., Cheng, Z. R., Mirczuk, S. M., …Menzies-Gow, N. J. (2018). Seasonal and dietary influences on adipose tissue and systemic gene expression in control and previously laminitic ponies. Journal of Equine Veterinary Science, https://doi.org/10.1016/j.jevs.2018.06.009

The aims of the study were to determine whether adipose tissue global gene expression (i) differs between never laminitic (NL) and previously laminitic (PL) ponies; (ii) is influenced by season and/or a diet designed to simulate spring grass and (iii... Read More about Seasonal and dietary influences on adipose tissue and systemic gene expression in control and previously laminitic ponies.

Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1 (2018)
Journal Article
Lawson, J. S., Syme, H. M., Wheeler-Jones, C. P. D., & Elliott, J. (2018). Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1. BMC Veterinary Research, 14, 76. https://doi.org/10.1186/s12917-018-1387-2

Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matrix in renal fibrosis... Read More about Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1.

Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease (2018)
Journal Article
Van Den Broek, D. H. N., Geddes, R. F., Williams, T. L., Chang, Y. M., Elliott, J., & Jepson, R. E. (2018). Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease. Journal of Veterinary Internal Medicine, 32(2), 727-735. https://doi.org/10.1111/jvim.15051

Background: Hypercalcemia is commonly associated with chronic kidney disease (CKD) in cats. Objectives: To explore the calcitonin response to naturally occurring ionized hypercalcemia in cats with azotemic CKD, and to assess the relationship of... Read More about Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease.

Associations between single nucleotide polymorphisms in the calcium sensing receptor and chronic kidney disease-mineral and bone disorder in cats (2018)
Journal Article
Geddes, R. F., Jepson, R. E., Forcada, Y., Elliott, J., & Syme, H. M. (2018). Associations between single nucleotide polymorphisms in the calcium sensing receptor and chronic kidney disease-mineral and bone disorder in cats. https://doi.org/10.1016/j.tvjl.2018.02.010

Feline chronic kidney disease (CKD) is associated with high variability in severity of CKD-mineral and bone disorder (CKD-MBD). The calcium sensing receptor (CaSR) regulates circulating parathyroid hormone (PTH) and calcium concentrations. Single nuc... Read More about Associations between single nucleotide polymorphisms in the calcium sensing receptor and chronic kidney disease-mineral and bone disorder in cats.

Plasma adrenocorticotropic hormone (ACTH) concentrations in ponies measured by two different assays suggests seasonal cross reactivity or interference (2018)
Journal Article
Knowles, E. J., Moreton-Clack, M. C., Shaw, S., Harris, P. A., Elliott, J., & Menzies-Gow, N. J. (2018). Plasma adrenocorticotropic hormone (ACTH) concentrations in ponies measured by two different assays suggests seasonal cross reactivity or interference. Equine Veterinary Journal, 50(5), 672-677. https://doi.org/10.1111/evj.12797