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Meridianin C inhibits the growth of YD-10B human tongue cancer cells through macropinocytosis and the down-regulation of Dickkopf-related protein-3 (2018)
Journal Article
Park, N. S., Park, Y. K., Ramalingam, M., Yadav, A. K., Cho, H. R., Hong, V. S., …Jang, B. C. (2018). Meridianin C inhibits the growth of YD-10B human tongue cancer cells through macropinocytosis and the down-regulation of Dickkopf-related protein-3. Journal of Cellular and Molecular Medicine, 22(12), 5833-5846. https://doi.org/10.1111/jcmm.13854

Meridianin C is a marine natural product known for its anti‐cancer activity. At present, the anti‐tumour effects of meridianin C on oral squamous cell carcinoma are unknown. Here, we investigated the effect of meridianin C on the proliferation of fou... Read More about Meridianin C inhibits the growth of YD-10B human tongue cancer cells through macropinocytosis and the down-regulation of Dickkopf-related protein-3.

How to Perform Umbilical Cord Arterial and Venous Blood Sampling in Neonatal Foals (2018)
Journal Article
Jeawon, S. S., Katz, L. M., Galvin, N. P., Cahalan, S. D., & Duggan, V. E. (2018). How to Perform Umbilical Cord Arterial and Venous Blood Sampling in Neonatal Foals. Journal of Equine Veterinary Science, https://doi.org/10.1016/j.jevs.2018.11.003

Umbilical cord arterial and venous blood gas analysis is a commonly performed procedure in human neonatal medicine to help ascertain a newborn infant’s oxygenation and acid-base status prior to birth. Defined protocols for performing the procedure ha... Read More about How to Perform Umbilical Cord Arterial and Venous Blood Sampling in Neonatal Foals.

Genomes of trombidid mites reveal novel predicted allergens and laterally-transferred genes associated with secondary metabolism (2018)
Journal Article
Dong, X., Chaisiri, K., Xia, D., Armstrong, S. D., Fang, Y., Donnelly, M. J., …Makepeace, B. L. (2018). Genomes of trombidid mites reveal novel predicted allergens and laterally-transferred genes associated with secondary metabolism. GigaScience, 7(12), https://doi.org/10.1093/gigascience/giy127

Trombidid mites have a unique lifecycle in which only the larval stage is ectoparasitic. In the superfamily Trombiculoidea (“chiggers”), the larvae feed preferentially on vertebrates, including humans. Species in the genus Leptotrombidium are vectors... Read More about Genomes of trombidid mites reveal novel predicted allergens and laterally-transferred genes associated with secondary metabolism.

A second KRT71 allele in curly coated dogs (2018)
Journal Article
Bauer, A., Hadji Rasouliha, S., Brunner, M. T., Jagannathan, V., Bucher, I., Bannoehr, J., …Leeb, T. (2018). A second KRT71 allele in curly coated dogs. Animal Genetics, 50(1), 97-100. https://doi.org/10.1111/age.12743

Major characteristics of coat variation in dogs can be explained by variants in only a few genes. Until now, only one missense variant in the KRT71 gene, p.Arg151Trp, has been reported to cause curly hair in dogs. However, this variant does not expla... Read More about A second KRT71 allele in curly coated dogs.

Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators (2018)
Journal Article
Baker, K. R., Jana, B., Hansen, A. M., Vissing, K. J., Nielsen, H. M., Franzyk, H., & Guardabassi, L. (2018). Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators. International Journal of Antimicrobial Agents, 53(6), 868-872. https://doi.org/10.1016/j.ijantimicag.2018.10.025

Gram-negative bacterial pathogens are intrinsically resistant to several antibiotics that are not able to penetrate the cell envelope barrier. The aim of this study was to identify peptides that at low concentrations induce susceptibility to these an... Read More about Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators.

Dysregulated cancer cell transdifferentiation into erythrocytes is an additional metabolic stress in hepatocellular carcinoma (2018)
Journal Article
Hughes, A., & Dhoot, G. K. (2018). Dysregulated cancer cell transdifferentiation into erythrocytes is an additional metabolic stress in hepatocellular carcinoma. Tumor Biology, 40(11), https://doi.org/10.1177/1010428318811467

A number of human and canine hepatocellular carcinoma tissues showed clear signs of hypoxia indicated by HIF1α-activation and the presence of large clusters of cells resembling erythrocytes at different stages of nuclear elimination without any defin... Read More about Dysregulated cancer cell transdifferentiation into erythrocytes is an additional metabolic stress in hepatocellular carcinoma.

Holter monitoring demonstrates that ventricular arrhythmias are common in cats with decompensated and compensated hypertrophic cardiomyopathy (2018)
Journal Article
Bartoszuk, U., Keene, B. W., Toaldo, M. B., Pereira, N., Summerfield, N., Novo Matos, J., & Glaus, T. M. (2018). Holter monitoring demonstrates that ventricular arrhythmias are common in cats with decompensated and compensated hypertrophic cardiomyopathy. https://doi.org/10.1016/j.tvjl.2018.11.005

Arrhythmias can complicate cardiac disease in cats and are a potential cause of sudden death. The aim of this study was to evaluate the presence and nature of cardiac arrhythmias, and the potential correlation between plasma serum troponin I (cTnI) c... Read More about Holter monitoring demonstrates that ventricular arrhythmias are common in cats with decompensated and compensated hypertrophic cardiomyopathy.

Anatomy Teaching, a “Model” Answer? Evaluating “Geoff”, a Painted Anatomical Horse, as a Tool for Enhancing Topographical Anatomy Learning (2018)
Journal Article
Bietzk, E., Weller, R., Simons, V., & Channon, S. B. (2018). Anatomy Teaching, a “Model” Answer? Evaluating “Geoff”, a Painted Anatomical Horse, as a Tool for Enhancing Topographical Anatomy Learning. Anatomical Sciences Education, https://doi.org/10.1002/ase.1823

Development of new methods for anatomy teaching is increasingly important as we look to modernize and supplement traditional teaching methods. In this study, a life‐sized equine model, “Geoff” was painted with surface and deep anatomical structures w... Read More about Anatomy Teaching, a “Model” Answer? Evaluating “Geoff”, a Painted Anatomical Horse, as a Tool for Enhancing Topographical Anatomy Learning.

Veterinary care of guinea pigs. Part 1: husbandry, stabilisation and diagnostics (2018)
Journal Article
Edis, A., & Pellett, A. (2018). Veterinary care of guinea pigs. Part 1: husbandry, stabilisation and diagnostics. Companion Animal, 23(11), https://doi.org/10.12968/coan.2018.23.11.649

Guinea pigs (Cavea porcellus) are popular pets within the UK. Owner expectations regarding advice and treatment for this species is increasing, and they may be presented to the veterinary clinic both for routine health checks and for treatment of ill... Read More about Veterinary care of guinea pigs. Part 1: husbandry, stabilisation and diagnostics.

Malignant Cutaneous Peripheral Nerve Sheath Tumour with Rhabdomyosarcomatous Differentiation (Triton Tumour) in a Domestic Cat (2018)
Journal Article
Stoll, A. L., Suárez-Bonnet, A., Summers, B. A., & Priestnall, S. L. (2018). Malignant Cutaneous Peripheral Nerve Sheath Tumour with Rhabdomyosarcomatous Differentiation (Triton Tumour) in a Domestic Cat. Journal of Comparative Pathology, 165, 1-5. https://doi.org/10.1016/j.jcpa.2018.09.003

Divergent differentiation is encountered frequently within human malignant peripheral nerve sheath tumours (MPNSTs). The new component is often a rhabdomyosarcoma, but in animals this specific form of divergent differentiation within MPNSTs has only... Read More about Malignant Cutaneous Peripheral Nerve Sheath Tumour with Rhabdomyosarcomatous Differentiation (Triton Tumour) in a Domestic Cat.

Cancellous bone and theropod dinosaur locomotion. Part I—an examination of cancellous bone architecture in the hindlimb bones of theropods (2018)
Journal Article
Bishop, P. J., Hocknull, S. A., Clemente, C. J., Hutchinson, J. R., Farke, A. A., Beck, B. R., …Lloyd, D. G. (2018). Cancellous bone and theropod dinosaur locomotion. Part I—an examination of cancellous bone architecture in the hindlimb bones of theropods. PeerJ, 6, e5778. https://doi.org/10.7717/peerj.5778

This paper is the first of a three-part series that investigates the architecture of cancellous (‘spongy’) bone in the main hindlimb bones of theropod dinosaurs, and uses cancellous bone architectural patterns to infer locomotor biomechanics in extin... Read More about Cancellous bone and theropod dinosaur locomotion. Part I—an examination of cancellous bone architecture in the hindlimb bones of theropods.

Cancellous bone and theropod dinosaur locomotion. Part III—Inferring posture and locomotor biomechanics in extinct theropods, and its evolution on the line to birds (2018)
Journal Article
Bishop, P. J., Hocknull, S. A., Clemente, C. J., Hutchinson, J. R., Farke, A. A., Beck, B. R., …Lloyd, D. G. (2018). Cancellous bone and theropod dinosaur locomotion. Part III—Inferring posture and locomotor biomechanics in extinct theropods, and its evolution on the line to birds. PeerJ, 6, e5777. https://doi.org/10.7717/peerj.5777

This paper is the last of a three-part series that investigates the architecture of cancellous bone in the main hindlimb bones of theropod dinosaurs, and uses cancellous bone architectural patterns to infer locomotor biomechanics in extinct non-avian... Read More about Cancellous bone and theropod dinosaur locomotion. Part III—Inferring posture and locomotor biomechanics in extinct theropods, and its evolution on the line to birds.

Cancellous bone and theropod dinosaur locomotion. Part II—a new approach to inferring posture and locomotor biomechanics in extinct tetrapod vertebrates (2018)
Journal Article
Bishop, P. J., Hocknull, S. A., Clemente, C. J., Hutchinson, J. R., Barrett, R. S., & Lloyd, D. G. (2018). Cancellous bone and theropod dinosaur locomotion. Part II—a new approach to inferring posture and locomotor biomechanics in extinct tetrapod vertebrates. PeerJ, 6, e5779. https://doi.org/10.7717/peerj.5779

This paper is the second of a three-part series that investigates the architecture of cancellous bone in the main hindlimb bones of theropod dinosaurs, and uses cancellous bone architectural patterns to infer locomotor biomechanics in extinct non-avi... Read More about Cancellous bone and theropod dinosaur locomotion. Part II—a new approach to inferring posture and locomotor biomechanics in extinct tetrapod vertebrates.

Like a hole in the head: Development, evolutionary implications and diseases of the cranial foramina (2018)
Journal Article
McGonnell, I. M., & Akbareian, S. E. (2018). Like a hole in the head: Development, evolutionary implications and diseases of the cranial foramina. https://doi.org/10.1016/j.semcdb.2018.08.011

Cranial foramina are holes in the skull through which nerves and blood vessels pass to reach both deep and superficial tissues. They are often overlooked in the literature; however they are complex structures that form within the developing cranial b... Read More about Like a hole in the head: Development, evolutionary implications and diseases of the cranial foramina.