Vesicle trafficking and pathways to neurodegeneration
(2021)
Journal Article
Blackstone, C., Elwood, F., Plun-Favreau, H., & Lewis, P. A. (2021). Vesicle trafficking and pathways to neurodegeneration. Molecular Neurodegeneration, 16(1), https://doi.org/10.1186/s13024-021-00480-1
All Outputs (513)
The effect of strip grazing on physical activity and behaviour in ponies (2021)
Journal Article
Cameron, A., Longland, A., Pfau, T., Pinnegar, S., Brackston, I., Hockenhull, J., …Menzies-Gow, N. J. (2021). The effect of strip grazing on physical activity and behaviour in ponies. Journal of Equine Veterinary Science, 103745. https://doi.org/10.1016/j.jevs.2021.103745This work aimed to determine the effect of strip grazing on physical activity in ponies using behavioural observations alongside accelerometers positioned at the poll. In study one, ten British native breed ponies were randomly assigned to paddock A... Read More about The effect of strip grazing on physical activity and behaviour in ponies.
Molecular basis for DarT ADP-ribosylation of a DNA base (2021)
Journal Article
Schuller, M., Butler, R., Ariza, A., Tromans-Coia, C., Jankevicius, G., Claridge, T., …Ahel, I. (2021). Molecular basis for DarT ADP-ribosylation of a DNA base. Nature, https://doi.org/10.1038/s41586-021-03825-4ADP-ribosyltransferases (ARTs) utilise NAD+ to catalyse substrate ADP-ribosylation, thereby regulating cellular pathways or contributing to toxin-mediated pathogenicity of bacteria. Reversible ADP-ribosylation has traditionally been considered a prot... Read More about Molecular basis for DarT ADP-ribosylation of a DNA base.
Sciatic neurectomy-related cortical bone loss exhibits delayed onset yet stabilises more rapidly than trabecular bone (2021)
Journal Article
Monzem, S., Javaheri, B., de Souza, R. L., & Pitsillides, A. A. (2021). Sciatic neurectomy-related cortical bone loss exhibits delayed onset yet stabilises more rapidly than trabecular bone. Bone Reports, 101116. https://doi.org/10.1016/j.bonr.2021.101116Disuse osteoporosis occurs after extended periods of bed rest or nerve damage leading to increased risk of fracture. It remains to be established, however, whether the trajectory of bone loss is equivalent in bone's cortical and trabecular compartmen... Read More about Sciatic neurectomy-related cortical bone loss exhibits delayed onset yet stabilises more rapidly than trabecular bone.
Dental Disease in dogs [Infographic] (2021)
Other
O'Neill, D., Mitchell, C. E., Humphrey, J., Church, D., Brodbelt, D., & Pegram, C. (2021). Dental Disease in dogs [Infographic]. [Infographic]
Epidemiology of periodontal disease in dogs in the UK primary‐care veterinary setting (2021)
Journal Article
O'Neill, D. G., Mitchell, C. E., Humphrey, J., Church, D. B., Brodbelt, D. C., & Pegram, C. (in press). Epidemiology of periodontal disease in dogs in the UK primary‐care veterinary setting. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13405
Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom (2021)
Dataset
O'Neill, D. Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom. [Dataset]
Using Qualitative System Dynamics Analysis to Promote Inclusive Livestock Value Chains: A Case Study of the South African Broiler Value Chain (2021)
Journal Article
Cuevas Garcia-Dorado, S., Queenan, K., Shankar, B., Häsler, B., Mabhaudhi, T., Cooper, G., & Slotow, R. (in press). Using Qualitative System Dynamics Analysis to Promote Inclusive Livestock Value Chains: A Case Study of the South African Broiler Value Chain. Frontiers in Sustainable Food Systems, 5, https://doi.org/10.3389/fsufs.2021.670756Livestock value chains globally are increasingly dualistic, with integrated market-leaders co-existing with comparatively disadvantaged small producers who, nevertheless, support rural livelihoods and food access, and can also contribute to more resi... Read More about Using Qualitative System Dynamics Analysis to Promote Inclusive Livestock Value Chains: A Case Study of the South African Broiler Value Chain.
A Retrospective Study Of Morbidity And Mortality Identified At Postmortem Examination Of Captive Langurs From Six UK Zoological Institutions: A Nineteen Year Review (2021)
Journal Article
Pereira, M., Stidworthy, M., Denk, D., Spiro, S., Guthrie, A., & Patterson, S. (in press). A Retrospective Study Of Morbidity And Mortality Identified At Postmortem Examination Of Captive Langurs From Six UK Zoological Institutions: A Nineteen Year Review. Journal of Zoo and Wildlife Medicine,Langurs are Asian primates belonging to the Colobinae subfamily. Langur populations are declining, with most species categorized as threatened by the IUCN. Investigation into the threats to population viability and sustainability would be beneficial... Read More about A Retrospective Study Of Morbidity And Mortality Identified At Postmortem Examination Of Captive Langurs From Six UK Zoological Institutions: A Nineteen Year Review.
Ethics: use and misuse of assisted reproductive techniques across species (2021)
Journal Article
Campbell, M. L. H. (2021). Ethics: use and misuse of assisted reproductive techniques across species. Reproduction and Fertility, 2(3), C23-C28. https://doi.org/10.1530/raf-21-0004The boundaries of what we are able to do using ARTs are fast-moving. In both human and veterinary medicine, this presents a fundamental question: 'Just because we can, should we?' or, to rephrase the same question: 'How can we distinguish between wha... Read More about Ethics: use and misuse of assisted reproductive techniques across species.
Closely related Lak megaphages replicate in the microbiomes of diverse animals (2021)
Journal Article
Crisci, M. A., Chen, L., Devoto, A. E., Borges, A. L., Bordin, N., Sachdeva, R., …Santini, J. M. (2021). Closely related Lak megaphages replicate in the microbiomes of diverse animals. iScience, 102875. https://doi.org/10.1016/j.isci.2021.102875
Structure-function specialisation of the interfascicular matrix in the human achilles tendon (2021)
Journal Article
Patel, D., Zamboulis, D. E., Spiesz, E. M., Birch, H. L., Clegg, P. D., Thorpe, C. T., & Screen, H. R. (2021). Structure-function specialisation of the interfascicular matrix in the human achilles tendon. Acta Biomaterialia, https://doi.org/10.1016/j.actbio.2021.07.019
Abrogation of LRRK2 dependent Rab10 phosphorylation with TLR4 activation and alterations in evoked cytokine release in immune cells (2021)
Journal Article
Nazish, I., Arber, C., Piers, T. M., Warner, T. T., Hardy, J. A., Lewis, P. A., …Bandopadhyay, R. (2021). Abrogation of LRRK2 dependent Rab10 phosphorylation with TLR4 activation and alterations in evoked cytokine release in immune cells. Neurochemistry International, 147, 105070. https://doi.org/10.1016/j.neuint.2021.105070
Connecting the Neurobiology of Developmental Brain Injury: Neuronal Arborisation as a Regulator of Dysfunction and Potential Therapeutic Target (2021)
Journal Article
Goikolea-Vives, A., & Stolp, H. B. (in press). Connecting the Neurobiology of Developmental Brain Injury: Neuronal Arborisation as a Regulator of Dysfunction and Potential Therapeutic Target. International Journal of Molecular Sciences, 22(15), 8220. https://doi.org/10.3390/ijms22158220
From structure to ætiology: a new window on the biology of leucine-rich repeat kinase 2 and Parkinson's disease (2021)
Journal Article
Herbst, S., & Lewis, P. A. (2021). From structure to ætiology: a new window on the biology of leucine-rich repeat kinase 2 and Parkinson's disease. Biochemical Journal, 478(14), 2945-2951. https://doi.org/10.1042/bcj20210383
Use of mechanical thresholds in a model of feline clinical acute pain, and their correlation with the Glasgow Feline Composite Measure Pain Scale scores. (2021)
Journal Article
Nicholls, D. (2021). Use of mechanical thresholds in a model of feline clinical acute pain, and their correlation with the Glasgow Feline Composite Measure Pain Scale scores. Journal of Feline Medicine and Surgery, https://doi.org/10.1177/1098612X211035051Objectives To evaluate the use of mechanical thresholds (MT), measured with the SMALGO, to measure pain, and to determine whether there was a correlation between MT and Glasgow Feline Composite Measure Pain Scale (CMPS–Feline) scores in cats underg... Read More about Use of mechanical thresholds in a model of feline clinical acute pain, and their correlation with the Glasgow Feline Composite Measure Pain Scale scores..
Development of a Method to Detect Mycobacterium paratuberculosis in the Blood of Farmed Deer Using Actiphage® Rapid (2021)
Journal Article
Kubala, A., Perehinec, T. M., Evans, C., Pirovano, A., Swift, B. M. C., & Rees, C. E. D. (2021). Development of a Method to Detect Mycobacterium paratuberculosis in the Blood of Farmed Deer Using Actiphage® Rapid. Frontiers in Veterinary Science, 8, https://doi.org/10.3389/fvets.2021.665697Mycobacterium avium subsp paratuberculosis (MAP) is the causative agent of Johne's disease, which is an economically and clinically relevant pathogen for commercial deer production. The purpose of this study was to develop a method that could be used... Read More about Development of a Method to Detect Mycobacterium paratuberculosis in the Blood of Farmed Deer Using Actiphage® Rapid.
MRI findings in a young dog with gliomatosis cerebri (2021)
Journal Article
Liatis, T., Hammond, G., Chapman, G. E., Cloquell Miro, A., Stalin, C., & Gutierrez‐Quintana, R. (in press). MRI findings in a young dog with gliomatosis cerebri. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13394
A citizen science trial to assess perception of wild penguin welfare (2021)
Journal Article
Nicol, C., Freire, R., Massaro, M., McDonald, S., & Trathan, P. (2021). A citizen science trial to assess perception of wild penguin welfare. Frontiers in Veterinary Science, https://doi.org/10.3389/fvets.2021.698685Wild penguins are facing increased threats to their populations and their welfare as a consequence of human activities. Understanding the perception of animal welfare is essential to identify ethical concerns related to the negative impact of anthr... Read More about A citizen science trial to assess perception of wild penguin welfare.
Development of Nanobodies Targeting Peste des Petits Ruminants Virus: The Prospect in Disease Diagnosis and Therapy (2021)
Journal Article
Kinimi, E., Muyldermans, S., Vincke, C., Odongo, S., Kock, R., Parida, S., …Misinzo, G. (in press). Development of Nanobodies Targeting Peste des Petits Ruminants Virus: The Prospect in Disease Diagnosis and Therapy. Animals, 11(8), 2206. https://doi.org/10.3390/ani11082206