All Outputs (2)

Regional modular responses in different bone compartments to the anabolic effect of PTH (1-34) and axial loading in mice (2023)
Journal Article
Monzem, S., Valkani, D., Evans, L., Chang, Y., & Pitsillides, A. (2023). Regional modular responses in different bone compartments to the anabolic effect of PTH (1-34) and axial loading in mice. BONE, 170, https://doi.org/10.1016/j.bone.2023.116720

Beneficial effects of intermittent parathyroid hormone (PTH) on bone mass and architecture are described to either simply add to, or to synergise with those of mechanical loading. We evaluate whether interaction with in vivo loading is reinforced by... Read More about Regional modular responses in different bone compartments to the anabolic effect of PTH (1-34) and axial loading in mice.

A new method for segmentation and analysis of bone callus in rodent fracture models using micro-CT (2022)
Journal Article
Hopkinson, M., Jones, G., Evans, L., Gohin, S., Magnusdottir, R., Salmon, P., …Pitsillides, A. (2022). A new method for segmentation and analysis of bone callus in rodent fracture models using micro-CT. Journal of Orthopaedic Research, https://doi.org/10.1002/jor.25507

Fracture burden has created a need to better understand bone repair processes under different pathophysiological states. Evaluation of structural and material properties of the mineralized callus, which is integral to restoring biomechanical stabilit... Read More about A new method for segmentation and analysis of bone callus in rodent fracture models using micro-CT.