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Outputs (37)

A method for isolating and culturing placental cells from failed early equine pregnancies (2016)
Journal Article
Rose, B. V., Cabrera-Sharp, V., Firth, M. J., Barrelet, F. E., Bate, S., Cameron, I. J., …De Mestre, A. M. (2016). A method for isolating and culturing placental cells from failed early equine pregnancies. Placenta, 38, 107-111. https://doi.org/10.1016/j.placenta.2015.12.014

Early pregnancy loss occurs in 6–10% of equine pregnancies making it the main cause of reproductive wastage. Despite this, reasons for the losses are known in only 16% of cases. Lack of viable conceptus material has inhibited investigations of many p... Read More about A method for isolating and culturing placental cells from failed early equine pregnancies.

SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion (2014)
Journal Article
Cabrera-Sharp, V., Read, J. E., Richardson, S., Kowalski, A. A., Antczak, D. F., Cartwright, J. E., …De Mestre, A. M. (2014). SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion. Endocrinology, 155(8), 3054-64. https://doi.org/10.1210/en.2013-2116

TGFβ superfamily proteins, acting via SMAD (Sma- and Mad-related protein)2/3 pathways, regulate placental function; however, the role of SMAD1/5/8 pathway in the placenta is unknown. This study investigated the functional role of bone morphogenetic p... Read More about SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion.

Glial Cells Missing Homologue 1 Is Induced in Differentiating Equine Chorionic Girdle Trophoblast Cells
Journal Article
De Mestre, A. M., Miller, D., Roberson, M. S., Liford, J., Chizmar, L. C., McLaughlin, K. E., & Antczak, D. F. Glial Cells Missing Homologue 1 Is Induced in Differentiating Equine Chorionic Girdle Trophoblast Cells. Biology of Reproduction, 80(2), 227-234. https://doi.org/10.1095/biolreprod.108.070920

The objective of this study was to identify transcription factors associated with differentiation of the chorionic girdle, the invasive form of equine trophoblast. The expression patterns of five transcription factors were determined on a panel of co... Read More about Glial Cells Missing Homologue 1 Is Induced in Differentiating Equine Chorionic Girdle Trophoblast Cells.