Outputs (37)

Regulatory T-cell-intrinsic amphiregulin is dispensable for suppressive function (2016)
Journal Article
Carney, K., Chang, Y. M., Wilson, S., Calnan, C., Reddy, P. S., Chan, W. Y., Gilmartin, T., Hernandez, G., Schaffer, L., Head, S. R., Morley, J., De Mestre, A. M., Affleck, K., & Garden, O. A. (2016). Regulatory T-cell-intrinsic amphiregulin is dispensable for suppressive function. Journal of Allergy and Clinical Immunology, 137(6), 1907-9. https://doi.org/10.1016/j.jaci.2016.01.030

A method for isolating and culturing placental cells from failed early equine pregnancies (2016)
Journal Article
Rose, B. V., Cabrera-Sharp, V., Firth, M. J., Barrelet, F. E., Bate, S., Cameron, I. J., Crabtree, J. R., Crowhurst, J., McGladdery, A. J., Neal, H., Pynn, J., Pynn, O. D., Smith, C., Wise, Z., Verheyen, K. L. P., Wathes, D. C., & De Mestre, A. M. (2016). A method for isolating and culturing placental cells from failed early equine pregnancies. Placenta, 38, 107-111. https://doi.org/10.1016/j.placenta.2015.12.014

Early pregnancy loss occurs in 6–10% of equine pregnancies making it the main cause of reproductive wastage. Despite this, reasons for the losses are known in only 16% of cases. Lack of viable conceptus material has inhibited investigations of many p... Read More about A method for isolating and culturing placental cells from failed early equine pregnancies.

SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion (2014)
Journal Article
Cabrera-Sharp, V., Read, J. E., Richardson, S., Kowalski, A. A., Antczak, D. F., Cartwright, J. E., Mukherjee, A., & De Mestre, A. M. (2014). SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion. Endocrinology, 155(8), 3054-64. https://doi.org/10.1210/en.2013-2116

TGFβ superfamily proteins, acting via SMAD (Sma- and Mad-related protein)2/3 pathways, regulate placental function; however, the role of SMAD1/5/8 pathway in the placenta is unknown. This study investigated the functional role of bone morphogenetic p... Read More about SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion.

The Equine Endometrial Cup Reaction: A Fetomaternal Signal of Significance
Book Chapter
Antczak, D. F., De Mestre, A. M., Wilsher, S., & Allen, W. R. The Equine Endometrial Cup Reaction: A Fetomaternal Signal of Significance. . https://doi.org/10.1146/annurev-animal-031412-103703

Expression of the heparan sulfate-degrading enzyme heparanase is induced in infiltrating CD4+ T cells in experimental autoimmune encephalomyelitis and regulated at the level of transcription by early growth response gene 1
Journal Article
De Mestre, A. M., Staykova, M. A., Hornby, J. R., Willenborg, D. O., & Hulett, M. D. Expression of the heparan sulfate-degrading enzyme heparanase is induced in infiltrating CD4+ T cells in experimental autoimmune encephalomyelitis and regulated at the level of transcription by early growth response gene 1. Journal of Leukocyte Biology, 82(5), 1289-1300. https://doi.org/10.1189/jlb.0507315

DIFFERENTIAL EXPRESSION OF THE TRANSCRIPTS ENCODING EPIDERMAL GROWTH FACTOR RECEPTOR AND ITS LIGANDS BY CD4(+) T HELPER SUBSETS IN RESPONSE TO T CELL RECEPTOR ENGAGEMENT
Presentation / Conference Contribution
Carney, K., Chan, W. Y., Singh, Y., Cobb, B. S., De Mestre, A. M., Affleck, K., & Garden, O. A. DIFFERENTIAL EXPRESSION OF THE TRANSCRIPTS ENCODING EPIDERMAL GROWTH FACTOR RECEPTOR AND ITS LIGANDS BY CD4(+) T HELPER SUBSETS IN RESPONSE TO T CELL RECEPTOR ENGAGEMENT

Clinical presentation, treatment and possible causes of persistent endometrial cups illustrated by two cases
Journal Article
Crabtree, J. R., Chang, Y. M., & De Mestre, A. M. Clinical presentation, treatment and possible causes of persistent endometrial cups illustrated by two cases. Equine Veterinary Education, 24(5), 251-259. https://doi.org/10.1111/j.2042-3292.2011.00354.x

Functions of ectopically transplanted invasive horse trophoblast
Presentation / Conference Contribution
De Mestre, A. M., Hanlon, D., Adams, A. P., Runcan, E., Leadbeater, J. C., Erb, N. H., Costa, C. C., Miller, D., Allen, W. R., & Antczak, D. F. Functions of ectopically transplanted invasive horse trophoblast

Split immunological tolerance to trophoblast
Journal Article
De Mestre, A. M., Noronha, L., Wagner, B., & Antczak, D. F. Split immunological tolerance to trophoblast. International Journal of Developmental Biology, 54(2-3), 445-455. https://doi.org/10.1387/ijdb.082795ad

MODULATION OF LYMPHOCYTE PROLIFERATION AND CYTOKINE EXPRESSION BY PLACENTAL TROPHOBLAST CELLS AIDS IN MATERNAL-FETAL TOLERANCE
Presentation / Conference Contribution
Robbin, M. G., Lawrence, R. A., Wagner, B., Antczak, D. F., & De Mestre, A. M. MODULATION OF LYMPHOCYTE PROLIFERATION AND CYTOKINE EXPRESSION BY PLACENTAL TROPHOBLAST CELLS AIDS IN MATERNAL-FETAL TOLERANCE