Outputs (23)

Role of Dicer Enzyme in the Regulation of Store Operated Calcium Entry (SOCE) in CD4+ T Cells (2016)
Journal Article
Zhang, S., Al-Maghout, T., Zhou, Y., Bissinger, R., Abousaab, A., Salker, M. S., Pelzl, L., Cobb, B. S., Cheng, A., Singh, Y., & Lang, F. (2016). Role of Dicer Enzyme in the Regulation of Store Operated Calcium Entry (SOCE) in CD4+ T Cells. https://doi.org/10.1159/000447840

MicroRNAs regulate T-cell production of interleukin-9 and identify hypoxia-inducible factor-2a as an important regulator of T helper 9 and regularoty T-cell differentiation (2016)
Journal Article
Singh, Y., Garden, O. A., Lang, F., & Cobb, B. S. (2016). MicroRNAs regulate T-cell production of interleukin-9 and identify hypoxia-inducible factor-2a as an important regulator of T helper 9 and regularoty T-cell differentiation. Immunology, 149(1), 74-86. https://doi.org/10.1111/imm.12631

Transduction of helper T cells as a genetic approach to study mechanisms controlling their differentiation and function (2016)
Journal Article
Singh, Y., Lang, F., Garden, O. A., & Cobb, B. S. (2016). Transduction of helper T cells as a genetic approach to study mechanisms controlling their differentiation and function. Journal of Visualized Experiments, 117, https://doi.org/10.3791/54698

MicroRNA-15b/16 Enhances the Induction of Regulatory T Cells by Regulating the Expression of Rictor and mTOR (2015)
Journal Article
Singh, Y., Garden, O. A., Lang, F., & Cobb, B. S. (2015). MicroRNA-15b/16 Enhances the Induction of Regulatory T Cells by Regulating the Expression of Rictor and mTOR. Journal of Immunology, 195(12), 5667-5677. https://doi.org/10.4049/jimmunol.1401875

CD4(+) regulatory T cells (Tregs) are essential for controlling immune responses and preventing autoimmunity. Their development requires regulation of gene expression by microRNAs (miRNAs). To understand miRNA function in Treg development, we searche... Read More about MicroRNA-15b/16 Enhances the Induction of Regulatory T Cells by Regulating the Expression of Rictor and mTOR.

An Early Developmental Role for miRNAs in the Maintenance of Extraembryonic Stem Cells in the Mouse Embryo
Journal Article
Spruce, T., Pernaute, B., Di-Gregorio, A., Cobb, B. S., Merkenschlager, M., & Manzanares, M. An Early Developmental Role for miRNAs in the Maintenance of Extraembryonic Stem Cells in the Mouse Embryo. Developmental Cell, 19(2), 207-219. https://doi.org/10.1016/j.devcel.2010.07.014

Cohesins functionally associate with CTCF on mammalian chromosome arms
Journal Article
Parelho, V., Hadjur, S., Spivakov, M., Leleu, M., Sauer, S., Gregson, H. C., Jarmuz, A., Canzonetta, C., Webster, Z., Nesterova, T. B., Cobb, B. S., Yokomori, K., Dillon, N., Aragon, L., Fisher, A. G., & Merkenschlager, M. (in press). Cohesins functionally associate with CTCF on mammalian chromosome arms. Cell, 132(3), 422-433. https://doi.org/10.1016/j.cell.2008.01.011

Small RNAs Control Sodium Channel Expression, Nociceptor Excitability, and Pain Thresholds
Journal Article
Zhao, J., Lee, M. C., Momin, A., Cendan, C. M., Shepherd, S. T., Baker, M. D., Asante, C., Bee, L., Bethry, A., Perkins, J. R., Nassar, M. A., Abrahamsen, B., Dickenson, A., Cobb, B. S., Merkenschlager, M., & Wood, J. N. Small RNAs Control Sodium Channel Expression, Nociceptor Excitability, and Pain Thresholds. Journal of Neuroscience, 30(32), 10860-10871. https://doi.org/10.1523/jneurosci.1980-10.2010

Runx proteins regulate Foxp3 expression
Journal Article
Bruno, L., Mazzarella, L., Hoogenkamp, M., Hertweck, A., Cobb, B. S., Sauer, S., Hadjur, S., Leleu, M., Naoe, Y., Telfer, J. C., Bonifer, C., Taniuchi, L., Fisher, A. G., & Merkenschlager, M. (in press). Runx proteins regulate Foxp3 expression. Journal of Experimental Medicine, 206(11), 2329-37. https://doi.org/10.1084/jem.20090226

Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus
Journal Article
Hadjur, S., Williams, L., Ryan, N. K., Cobb, B. S., Sexton, T., Fraser, P., Fisher, A. G., & Merkenschlager, M. (in press). Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus. Nature, 460(7253), 410-3. https://doi.org/10.1038/nature08079

A reappraisal of evidence for probabilistic models of allelic exclusion.
Journal Article
Taylor, B., Cobb, B. S., Bruno, L., Webste, Z., Fisher, A. G., & Merkenschlager, M. A reappraisal of evidence for probabilistic models of allelic exclusion. https://doi.org/10.1073/pnas.0808764105