Outputs (96)

Evaluation of VEGF-Mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells
Journal Article
Clarkin, C. E., Emery, R. J., Pitsillides, A. A., & Wheeler-Jones, C. P. D. Evaluation of VEGF-Mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells. Journal of Cellular Physiology, 214(2), 537-544. https://doi.org/10.1002/jcp.21234

Communication between endothelial and bone cells is crucial for controlling vascular supply during bone growth, remodeling, and repair but the molecular mechanisms coordinating this intercellular crosstalk remain ill-defined. We have used primary hum... Read More about Evaluation of VEGF-Mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells.

Ammonia impairs neutrophil phagocytic function in liver disease
Journal Article
Shawcross, D. L., Wright, G. A. K., Stadlbauer, V., Hodges, S. J., Davies, N. A., Wheeler-Jones, C. P. D., …Jalan, R. Ammonia impairs neutrophil phagocytic function in liver disease. Hepatology, 48(4), 1202-12. https://doi.org/10.1002/hep.22474

Regulation of endothelial prostacyclin synthesis by Protease-activated receptors: mechanisms and significance
Journal Article
Wheeler-Jones, C. P. D. Regulation of endothelial prostacyclin synthesis by Protease-activated receptors: mechanisms and significance

The cellular actions of serine proteases are mediated through activation of a novel family of four G protein-coupled receptors known as protease-activated receptors (PARs). PARs are emerging as important modulators of diverse biological functions and... Read More about Regulation of endothelial prostacyclin synthesis by Protease-activated receptors: mechanisms and significance.

Dietary fats induce human monocyte activation in vitro
Conference Proceeding
Bentley, C., Bejta, F., De Pascale, C., Avella, M. A., Wheeler-Jones, C. P. D., Botham, K. M., & Lawson, C. Dietary fats induce human monocyte activation in vitro

Introduction to the Biochemical Society Focused Meeting on Diet and Cardiovascular Health: Chylomicron Remnants and Their Emerging Roles in Vascular Dysfunction in Atherosclerosis
Conference Proceeding
Botham, K. M., & Wheeler-Jones, C. P. D. Introduction to the Biochemical Society Focused Meeting on Diet and Cardiovascular Health: Chylomicron Remnants and Their Emerging Roles in Vascular Dysfunction in Atherosclerosis

Endotoxin-induced activation of equine platelets: evidence for direct activation of p38 MAPK pathways and vasoactive mediator production
Journal Article
Brooks, A. C., Menzies-Gow, N. J., Wheeler-Jones, C. P. D., Bailey, S. R., Cunningham, F. M., & Elliott, J. Endotoxin-induced activation of equine platelets: evidence for direct activation of p38 MAPK pathways and vasoactive mediator production. Inflammation Research, 56(4), 154-161. https://doi.org/10.1007/s00011-006-6151-6