Outputs (38)

Optimisation of the differing conditions required for bone formation in vitro by primary osteoblasts from mice and rats
Journal Article
Orriss, I. R., Hajjawi, M. O. R., Huesa, C., MacRae, V. E., & Arnett, T. R. (in press). Optimisation of the differing conditions required for bone formation in vitro by primary osteoblasts from mice and rats. International Journal of Molecular Medicine, 34(5), 1201-1208. https://doi.org/10.3892/ijmm.2014.1926

The in vitro culture of calvarial osteoblasts from neonatal rodents remains an important method for studying the regulation of bone formation. The widespread use of transgenic mice has created a particular need for a reliable, simple method that allo... Read More about Optimisation of the differing conditions required for bone formation in vitro by primary osteoblasts from mice and rats.

Strontium and osteoblast function
Journal Article
Wornham, D., Hajjawi, M. O. R., Orriss, I. R., & Arnett, T. R. Strontium and osteoblast function. Osteoporosis International, https://doi.org/10.1007/s00198-015-3120-3

FIBRILLIN-1 IS EXPRESSED IN CARTILAGE AND MUTATION LEADS TO OA DEVELOPMENT
Presentation / Conference Contribution
Ramanayake, W., Jones, H., Orriss, I. R., Arnett, T., Pitsillides, A. A., Denton, C., Abraham, D., & Poulet, B. FIBRILLIN-1 IS EXPRESSED IN CARTILAGE AND MUTATION LEADS TO OA DEVELOPMENT

The role of purinergic signalling in the musculoskeletal system
Journal Article
Orriss, I. R. (in press). The role of purinergic signalling in the musculoskeletal system. https://doi.org/10.1016/j.autneu.2015.04.013

Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation
Journal Article
Orriss, I. R., Arnett, T. R., George, J., & Witham, M. D. (in press). Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation. Experimental Cell Research, 342(2), 166-174. https://doi.org/10.1016/j.yexcr.2016.03.004

Design and fabrication of 3D-printed anatomically shaped lumbar cage for intervertebra disc (IVD) degeneration treatment
Journal Article
Serra, T., Capelli, C., Toumpaniari, R., Orriss, I. R., Leong, J., Dalgarno, K., & Kalaskar, D. (in press). Design and fabrication of 3D-printed anatomically shaped lumbar cage for intervertebra disc (IVD) degeneration treatment. Biofabrication, 8(3), https://doi.org/10.1088/1758-5090/8/3/035001

Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice
Journal Article
Orriss, I. R., Lanham, S. A., Savery, D., Greene, N. D. E., Stanier, P., Oreffo, R., Copp, A. J., & Galea, G. L. (in press). Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice. https://doi.org/10.1038/s41598-018-21718-x

Fractures are a common comorbidity in children with the neural tube defect (NTD) spina bifida. Mutations in the Wnt/planar cell polarity (PCP) pathway contribute to NTDs in humans and mice, but whether this pathway independently determines bone mass... Read More about Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice.

The in vitro behaviour of canine osteoblasts derived from different bone types
Journal Article
Meeson, R. L., Perpétuo, I. P., Parsons, K. J., Orriss, I. R., Shah, M., Pitsillides, A. A., & Doube, M. (in press). The in vitro behaviour of canine osteoblasts derived from different bone types. BMC Veterinary Research, 15(114), https://doi.org/10.1186/s12917-019-1857-1