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Outputs (48)

Swing-leg trajectory of running guinea fowl suggest task-level priority of force regulation rather than disturbance rejection (2014)
Journal Article
Blum, Y., Vejdani, H. R., Birn-Jeffery, A. V., Hubicki, C. M., Hurst, J. W., & Daley, M. A. (2014). Swing-leg trajectory of running guinea fowl suggest task-level priority of force regulation rather than disturbance rejection. PLoS ONE, 9(6), e100399. https://doi.org/10.1371/journal.pone.0100399

To achieve robust and stable legged locomotion in uneven terrain, animals must effectively coordinate limb swing and stance phases, which involve distinct yet coupled dynamics. Recent theoretical studies have highlighted the critical influence of swi... Read More about Swing-leg trajectory of running guinea fowl suggest task-level priority of force regulation rather than disturbance rejection.

Cardiovascular effects of dietary salt intake in aged healthy cats: a 2-year prospective randomized, blinded, and controlled study (2014)
Journal Article
Chetboul, V., Reynolds, B. S., Trehiou-Sechi, E., Nguyen, P., Concordet, D., Sampedrano, C. C., …Lefebvre, H. P. (2014). Cardiovascular effects of dietary salt intake in aged healthy cats: a 2-year prospective randomized, blinded, and controlled study. PLoS ONE, 9(6), e97862. https://doi.org/10.1371/journal.pone.0097862

High salt dry expanded diets are commercially available for cats to increase water intake and urine volume, as part of the prevention or treatment of naturally occurring urinary stone formation (calcium oxalates and struvites). However, chronic high... Read More about Cardiovascular effects of dietary salt intake in aged healthy cats: a 2-year prospective randomized, blinded, and controlled study.

Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease (2014)
Journal Article
Kathrani, A., Lee, H., White, C., Catchpole, B., Murphy, A. M., German, A., …Allenspach, K. (2014). Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease. Veterinary Immunology and Immunopathology, 161(1-2), 32-41. https://doi.org/10.1016/j.vetimm.2014.06.003

The most important genetic associations that have been implicated to play a role in the etiology of Crohn's disease (CD) in humans are single nucleotide polymorphisms (SNPs) in nucleotide oligomerisation domain 2 (NOD2). The aim of this study was to... Read More about Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease.

CNS-targeted glucocorticoid reduces pathology in mouse model of amyotrophic lateral sclerosis (2014)
Journal Article
Evans, M. C., Gaillard, P. J., De Boer, M., Appeldoorn, C., Dorland, R., Sibson, N. R., …Stolp, H. B. (2014). CNS-targeted glucocorticoid reduces pathology in mouse model of amyotrophic lateral sclerosis. Acta Neuropathologica Communications, 2, 66. https://doi.org/10.1186/2051-5960-2-66

Hallmarks of CNS inflammation, including microglial and astrocyte activation, are prominent features in post-mortem tissue from amyotrophic lateral sclerosis (ALS) patients and in mice overexpressing mutant superoxide dismutase-1 (SOD1 G93A ). Admini... Read More about CNS-targeted glucocorticoid reduces pathology in mouse model of amyotrophic lateral sclerosis.

Appearance of the canine meninges in subtraction magnetic resonance images (2014)
Journal Article
Lamb, C. R., Lam, R. W., Keenihan, E. K., & Frean, S. P. (2014). Appearance of the canine meninges in subtraction magnetic resonance images. https://doi.org/10.1111/vru.12166

The canine meninges are not visible as discrete structures in noncontrast magnetic resonance (MR) images, and are incompletely visualized in T1‐weighted, postgadolinium images, reportedly appearing as short, thin curvilinear segments with minimal enh... Read More about Appearance of the canine meninges in subtraction magnetic resonance images.

Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration (2014)
Journal Article
Kenward, H., Pelligand, L., & Elliott, J. (2014). Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration. Experimental Brain Research, 232(8), 2685-2697. https://doi.org/10.1007/s00221-014-3961-6

Cisplatin is a highly emetogenic cancer chemotherapy agent, which is often used to induce nausea and emesis in animal models. The cytotoxic properties of cisplatin also cause adverse events that negatively impact on animal welfare preventing repeated... Read More about Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration.

Parkinson’s Disease-Linked Mutations in VPS35 Induce Dopaminergic Neurodegeneration (2014)
Journal Article
Tsika, E., Glauser, L., Moser, R., Fiser, A., Daniel, G., Sheerin, U., …Moore, D. J. (2014). Parkinson’s Disease-Linked Mutations in VPS35 Induce Dopaminergic Neurodegeneration. Human Molecular Genetics, 23(17), 4621-4638. https://doi.org/10.1093/hmg/ddu178

Mutations in the vacuolar protein sorting 35 homolog (VPS35) gene at the PARK17 locus, encoding a key component of the retromer complex, were recently identified as a new cause of late-onset, autosomal dominant Parkinson's disease (PD). Here we explo... Read More about Parkinson’s Disease-Linked Mutations in VPS35 Induce Dopaminergic Neurodegeneration.

Low Dose of Propranolol Does Not Affect Rat Osteotomy Healing and Callus Strength (2014)
Journal Article
Smitham, P., Crossfield, L., Hughes, G., Goodship, A., Blunn, G., & Chenu, C. (2014). Low Dose of Propranolol Does Not Affect Rat Osteotomy Healing and Callus Strength. Journal of Orthopaedic Research, 32(7), 887-893. https://doi.org/10.1002/jor.22619

Experimental studies suggest that the β‐blocker propranolol stimulates bone formation but little work has investigated its effect on fracture healing. In this study, we examined if a low dose of propranolol, previously shown to be preventive against... Read More about Low Dose of Propranolol Does Not Affect Rat Osteotomy Healing and Callus Strength.