Outputs (65)

Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity (2015)
Journal Article
Oguejiofor, C. F., Cheng, Z. R., Abudureyimu, A., Fouladi-Nashta, A. A., & Wathes, D. C. (2015). Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity. Biology of Reproduction, 93(4), https://doi.org/10.1095/biolreprod.115.128868

The dysregulation of endometrial immune response to bacterial lipopolysaccharide (LPS) has been implicated in uterine disease and infertility in the postpartum dairy cow, although the mechanisms are not clear. Here, we investigated whole-transcriptom... Read More about Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity.

Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide (2015)
Journal Article
Oguejiofor, C. F., Cheng, Z. R., Abudureyimu, A., Anstaett, O. L., Brownlie, J., Fouladi-Nashta, A. A., & Wathes, D. C. (2015). Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide. Biology of Reproduction, 93(4), https://doi.org/10.1095/biolreprod.115.128876

Infection with noncytopathic bovine viral diarrhea virus (ncpBVDV) is associated with uterine disease and infertility. This study investigated the influence of ncpBVDV on immune functions of the bovine endometrium by testing the response to bacterial... Read More about Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide.

PKA Phosphorylation of NCLX Reverses Mitochondrial Calcium Overload and Depolarization, Promoting Survival of PINK1-Deficient Dopaminergic Neurons (2015)
Journal Article
Kostic, M., Ludtmann, M. H. R., Bading, H., Hershfinkel, M., Steer, E., Chu, C. T., …Sekler, I. (2015). PKA Phosphorylation of NCLX Reverses Mitochondrial Calcium Overload and Depolarization, Promoting Survival of PINK1-Deficient Dopaminergic Neurons. Cell Reports, 13(2), 376-386. https://doi.org/10.1016/j.celrep.2015.08.079

Mitochondrial Ca2+ overload is a critical, preceding event in neuronal damage encountered during neurodegenerative and ischemic insults. We found that loss of PTEN-induced putative kinase 1 (PINK1) function, implicated in Parkinson disease, inhibits... Read More about PKA Phosphorylation of NCLX Reverses Mitochondrial Calcium Overload and Depolarization, Promoting Survival of PINK1-Deficient Dopaminergic Neurons.

Neutrophil Gelatinase-Associated Lipocalin in Dogs With Sepsis Undergoing Emergency Laparotomy: A Prospective Case–Control Study (2015)
Journal Article
Cortellini, S., Pelligand, L., Syme, H. M., Chang, Y. M., & Adamantos, S. E. (2015). Neutrophil Gelatinase-Associated Lipocalin in Dogs With Sepsis Undergoing Emergency Laparotomy: A Prospective Case–Control Study. Journal of Veterinary Internal Medicine, 29(6), 1595-1602. https://doi.org/10.1111/jvim.13638

Children and adults minimise activated muscle volume by selecting gait parameters that balance gross mechanical power and work demands (2015)
Journal Article
Hubel, T. Y., & Usherwood, J. R. (2015). Children and adults minimise activated muscle volume by selecting gait parameters that balance gross mechanical power and work demands. Journal of Experimental Biology, 218(PT 18), 2830-2839. https://doi.org/10.1242/jeb.122135

Terrestrial locomotion on legs is energetically expensive. Compared with cycling, or with locomotion in swimming or flying animals, walking and running are highly uneconomical. Legged gaits that minimise mechanical work have previously been identifie... Read More about Children and adults minimise activated muscle volume by selecting gait parameters that balance gross mechanical power and work demands.

Skinned fibres produce the same power and force as intact fibre bundles from muscle of wild rabbits (2015)
Journal Article
Curtin, N. A., Diack, R. A., West, T. G., Wilson, A. M., & Woledge, R. C. (2015). Skinned fibres produce the same power and force as intact fibre bundles from muscle of wild rabbits. Journal of Experimental Biology, 218, 2856-2863. https://doi.org/10.1242/jeb.121897

Skinned fibres have advantages for comparing the muscle properties of different animal species because they can be prepared from a needle biopsy taken under field conditions. However, it is not clear how well the contractile properties of skinned fib... Read More about Skinned fibres produce the same power and force as intact fibre bundles from muscle of wild rabbits.

Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury (2015)
Journal Article
Baburamani, A. A., Hurling, C., Stolp, H. B., Sobotka, K., Gressens, P., Hagberg, H., & Thornton, C. (2015). Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury. International Journal of Molecular Sciences, 16(9), 22509-22526. https://doi.org/10.3390/ijms160922509

Lessons from integrating behaviour and resource selection: activity-specific responses of African wild dogs to roads (2015)
Journal Article
Abrahms, B., Jordan, N. R., Golabek, K. A., McNutt, J. W., Wilson, A. M., & Brashares, J. S. (2015). Lessons from integrating behaviour and resource selection: activity-specific responses of African wild dogs to roads. Animal Conservation, 19, 247-255. https://doi.org/10.1111/acv.12235

Understanding how anthropogenic features affect species' abilities to move within landscapes is essential to conservation planning and requires accurate assessment of resource selection for movement by focal species. Yet, the extent to which an indiv... Read More about Lessons from integrating behaviour and resource selection: activity-specific responses of African wild dogs to roads.

Identification of mouse gaits using a novel force-sensing exercise wheel (2015)
Journal Article
Smith, B. J. H., Cullingford, L., & Usherwood, J. R. (2015). Identification of mouse gaits using a novel force-sensing exercise wheel. Journal of Applied Physiology, 119(6), 704-718. https://doi.org/10.1152/japplphysiol.01014.2014

The gaits that animals use can provide information on neurological and musculoskeletal disorders, as well as the biomechanics of locomotion. Mice are a common research model in many fields; however, there is no consensus in the literature on how (and... Read More about Identification of mouse gaits using a novel force-sensing exercise wheel.

FHL1 activates myostatin signalling in skeletal muscle and promotes atrophy (2015)
Journal Article
Lee, J. Y., Lori, D., Wells, D. J., & Kemp, P. R. (2015). FHL1 activates myostatin signalling in skeletal muscle and promotes atrophy. FEBS Open Bio, 5, 753-762. https://doi.org/10.1016/j.fob.2015.08.011

Myostatin is a TGFβ family ligand that reduces muscle mass. In cancer cells, TGFβ signalling is increased by the protein FHL1. Consequently, FHL1 may promote signalling by myostatin. We therefore tested the ability of FHL1 to regulate myostatin funct... Read More about FHL1 activates myostatin signalling in skeletal muscle and promotes atrophy.