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Outputs (159)

Urinary active transforming growth factor ß in feline chronic kidney disease (2016)
Journal Article
Lawson, J. S., Syme, H. M., Wheeler-Jones, C. P. D., & Elliott, J. (2016). Urinary active transforming growth factor ß in feline chronic kidney disease. https://doi.org/10.1016/j.tvjl.2016.02.004

The cytokine transforming growth factor beta 1 (TGF-β1) has been widely implicated in the development and progression of renal fibrosis in chronic kidney disease (CKD) in humans and in experimental models. The aims of this study were to assess the as... Read More about Urinary active transforming growth factor ß in feline chronic kidney disease.

Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney (2015)
Journal Article
Pelligand, L., Suemanotham, N., King, J. N., Seewald, W., Syme, H. M., Smith, K. C., Lees, P., & Elliott, J. (2015). Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney. BMC Veterinary Research, 11(296), https://doi.org/10.1186/s12917-015-0598-z

Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme (2015)
Journal Article
Sanchez-Lara, A. C., Elliott, J., Syme, H. M., Brown, C. A., & Haylor, J. L. (2015). Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme. Veterinary Pathology, 52(3), 513-523. https://doi.org/10.1177/0300985814542811

Chronic kidney disease is a major cause of morbidity and mortality in cats. Transglutaminase 2 (TG2) is a calcium-dependent enzyme proposed to mediate tubulointerstitial fibrosis in the kidney by cross-linking collagen fibrils. Postmortem kidney tiss... Read More about Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme.