Outputs (81)

Standard PK/PD concepts can be applied to determine a dosage regimen for a macrolide: the case of tulathromycin in the calf (2017)
Journal Article
Toutain, P. L., Potter, T. J., Pelligand, L., Lacroix, M., Illambas, J., & Lees, P. (2017). Standard PK/PD concepts can be applied to determine a dosage regimen for a macrolide: the case of tulathromycin in the calf. Journal of Veterinary Pharmacology and Therapeutics, 40(1), 16-27. https://doi.org/10.1111/jvp.12333

The pharmacokinetic (PK) profile of tulathromycin, administered to calves subcutaneously at the dosage of 2.5 mg/kg, was established in serum, inflamed (exudate), and noninflamed (transudate) fluids in a tissue cage model. The PK profile of tulathrom... Read More about Standard PK/PD concepts can be applied to determine a dosage regimen for a macrolide: the case of tulathromycin in the calf.

Comparison of standardised versus non-standardised methods for testing the in vitro potency of oxytetracycline against mannheimia haemolytica and pasteurella multocida (2016)
Journal Article
Lees, P., Illambas, J., Pelligand, L., & Toutain, P. L. (2016). Comparison of standardised versus non-standardised methods for testing the in vitro potency of oxytetracycline against mannheimia haemolytica and pasteurella multocida. https://doi.org/10.1016/j.tvjl.2016.11.006

Dogs attending primary-care practice in England with clinical signs suggestive of Chiari-like malformation/syringomyelia (2016)
Journal Article
Sanchis-Mora, S., Pelligand, L., Thomas, C. L., Volk, H. A., Abeyesinghe, S. M., Brodbelt, D. C., …O'Neill, D. G. (2016). Dogs attending primary-care practice in England with clinical signs suggestive of Chiari-like malformation/syringomyelia. Veterinary Record, 179(17), 436. https://doi.org/10.1136/vr.103651

Chiari-like malformation/syringomyelia (CM/SM) in dogs describes a developmental disorder that can cause pain and reduced quality of life. This retrospective study aimed to report the period prevalence, clinical signs and risk factors for diagnosis o... Read More about Dogs attending primary-care practice in England with clinical signs suggestive of Chiari-like malformation/syringomyelia.

Modeling of Large Pharmacokinetic Data Using Nonlinear Mixed-Effects: A Paradigm Shift in Veterinary Pharmacology. A Case Study With Robenacoxib in Cats (2016)
Journal Article
Pelligand, L., Soubret, A., King, J. N., Elliott, J., & Mochel, J. P. (2016). Modeling of Large Pharmacokinetic Data Using Nonlinear Mixed-Effects: A Paradigm Shift in Veterinary Pharmacology. A Case Study With Robenacoxib in Cats. https://doi.org/10.1002/psp4.12141

The objective of this study was to model the pharmacokinetics (PKs) of robenacoxib in cats using a nonlinear mixed‐effects (NLME) approach, leveraging all available information collected from cats receiving robenacoxib s.c. and/or i.v.: 47 densely sa... Read More about Modeling of Large Pharmacokinetic Data Using Nonlinear Mixed-Effects: A Paradigm Shift in Veterinary Pharmacology. A Case Study With Robenacoxib in Cats.

Factors influencing the relationship between the dose of amlodipine required for blood pressure control and change in blood pressure in hypertensive cats (2016)
Journal Article
Bijsmans, E. S., Doig, M., Jepson, R. E., Syme, H. M., Elliott, J., & Pelligand, L. (2016). Factors influencing the relationship between the dose of amlodipine required for blood pressure control and change in blood pressure in hypertensive cats. Journal of Veterinary Internal Medicine, 30(5), 1630-1636. https://doi.org/10.1111/jvim.14562

Veterinary Medicine Needs New Green Antimicrobial Drugs (2016)
Journal Article
Toutain, P. L., Ferran, A. A., Bousquet-Mélou, A., Pelligand, L., & Lees, P. (2016). Veterinary Medicine Needs New Green Antimicrobial Drugs. Frontiers in Microbiology, 7, 1196. https://doi.org/10.3389/fmicb.2016.01196

Controlling pain in cats (2016)
Journal Article
Drozdzynska, M., & Pelligand, L. (2016). Controlling pain in cats. In Practice, 38, 259-274. https://doi.org/10.1136/inp.i2807

Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney (2015)
Journal Article
Pelligand, L., Suemanotham, N., King, J. N., Seewald, W., Syme, H. M., Smith, K. C., …Elliott, J. (2015). Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney. BMC Veterinary Research, 11(296), https://doi.org/10.1186/s12917-015-0598-z

Neutrophil Gelatinase-Associated Lipocalin in Dogs With Sepsis Undergoing Emergency Laparotomy: A Prospective Case–Control Study (2015)
Journal Article
Cortellini, S., Pelligand, L., Syme, H. M., Chang, Y. M., & Adamantos, S. E. (2015). Neutrophil Gelatinase-Associated Lipocalin in Dogs With Sepsis Undergoing Emergency Laparotomy: A Prospective Case–Control Study. Journal of Veterinary Internal Medicine, 29(6), 1595-1602. https://doi.org/10.1111/jvim.13638

Nausea: Current knowledge of mechanisms, measurement and clinical impact (2015)
Journal Article
Kenward, H., Pelligand, L., Savary-Bataille, K., & Elliott, J. (2015). Nausea: Current knowledge of mechanisms, measurement and clinical impact. https://doi.org/10.1016/j.tvjl.2014.10.007