Aging enhances a mechanically-induced reduction in tendon strength by an active process involving matrix metalloproteinase activity
Journal Article
Dudhia, J., Scott, C. M., Draper, E. R. C., Heinegard, D., Pitsillides, A. A., & Smith, R. K. W. Aging enhances a mechanically-induced reduction in tendon strength by an active process involving matrix metalloproteinase activity. Aging Cell, 6(4), 547-556. https://doi.org/10.1111/j.1474-9726.2007.00307.x
Outputs (136)
Size isn't everything: The importance of the hindlimb accessory ligament of the deep digital flexor tendon
Journal Article
Smith, R. K. W., & Eliashar, E. Size isn't everything: The importance of the hindlimb accessory ligament of the deep digital flexor tendon. Equine Veterinary Education, 20(12), 625-626. https://doi.org/10.2746/095777308x387655
THE INFLUENCE OF AGEING IN TENDON HOMEOSTASIS AND THE RISK OF TENDON INJURY
Presentation / Conference Contribution
Smith, R. K. W., Dudhia, J., Scott, C. M., Draper, E., May, S. A., & Pitsillides, A. A. THE INFLUENCE OF AGEING IN TENDON HOMEOSTASIS AND THE RISK OF TENDON INJURY. International Journal of Experimental Pathology, 89(3), A25-A25
Evaluation of a new strategy to modulate skeletal development in Thoroughbred performance horses by imposing track-based exercise during growth
Journal Article
Rogers, C. W., Firth, E. C., McIlwraitht, C. W., Barneveld, A., Goodship, A. E., Kawcak, C. E., …Van Weeren, P. R. Evaluation of a new strategy to modulate skeletal development in Thoroughbred performance horses by imposing track-based exercise during growth. Equine Veterinary Journal, 40(2), 111-118. https://doi.org/10.2746/042516408x268923Reasons for performing study: No data exist on the intensity of exercise required or on possible harmful effects of increasing exercise in foals over the natural level when free at pasture.
The influence of exercise during growth on ultrasonographic parameters of the superficial digital flexor tendon of young Thoroughbred horses
Journal Article
Moffat, P. A., Firth, E. C., Rogers, C. W., Smith, R. K. W., Barneveld, A., Goodship, A. E., …Van Weeren, P. R. The influence of exercise during growth on ultrasonographic parameters of the superficial digital flexor tendon of young Thoroughbred horses. Equine Veterinary Journal, 40(2), 136-140. https://doi.org/10.2746/042516408x253109Reasons for performing study: Conditioning by early training may influence the composition of certain musculoskeletal tissues, but very few data exist on its effect during growth on tendon structure and function.
Diagnostic ultrasound of the limb joints, muscle and bone in horses
Journal Article
Smith, M., & Smith, R. K. W. Diagnostic ultrasound of the limb joints, muscle and bone in horses. In Practice, 30(3), 152-159DIAGNOSTIC ultrasonography for the musculoskeletal system in the horse was first used in the early 1980s. Initial applications were directed towards the diagnosis of flexor tendon and ligament injuries in the distal limb, but this modality is now com... Read More about Diagnostic ultrasound of the limb joints, muscle and bone in horses.
Principles of stem cell therapy in the horse - the science behind the technology
Journal Article
Smith, R. K. W. Principles of stem cell therapy in the horse - the science behind the technologyTendon and ligament overstrain injuries in the horse are appropriate diseases to consider for stem cell therapy because normal fibrous repair results in reduced functionality, typified by poorer performance and a high rate of re-injury. Exogenously a... Read More about Principles of stem cell therapy in the horse - the science behind the technology.
Stem cell therapy for tendon and ligament injuries in the horse - technique and outcome
Journal Article
Smith, R. K. W. Stem cell therapy for tendon and ligament injuries in the horse - technique and outcomeThe technique involves the collection of bone marrow from the sternum in the standing sedated horse, followed by isolation and expansion of the nucleated adherent cell population (containing the MSCs) in the laboratory. After approximately 2-3 weeks,... Read More about Stem cell therapy for tendon and ligament injuries in the horse - technique and outcome.
Intratendinous treatments - are they innocuous?
Journal Article
Smith, R. K. W. Intratendinous treatments - are they innocuous?. Equine Veterinary Education, 20(7), 392-392. https://doi.org/10.2746/095777308x331548
Skeletal physiology: responses to exercise and training
Book Chapter
Goodship, A. E., & Smith, R. K. W. Skeletal physiology: responses to exercise and training.