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Outputs (59)

Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease (2018)
Journal Article
Van Den Broek, D. H. N., Geddes, R. F., Williams, T. L., Chang, Y. M., Elliott, J., & Jepson, R. E. (2018). Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease. Journal of Veterinary Internal Medicine, 32(2), 727-735. https://doi.org/10.1111/jvim.15051

Background:
Hypercalcemia is commonly associated with chronic kidney disease (CKD) in cats.

Objectives:
To explore the calcitonin response to naturally occurring ionized hypercalcemia in cats with azotemic CKD, and to assess the relationship of... Read More about Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease.

Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs (2017)
Journal Article
Lee, K. C. L., Baker, L., Mallett, S., Riddell, A., Chowdary, P., Alibhai, H. I. K., …Agarwal, B. (2017). Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs. https://doi.org/10.1038/s41598-017-09508-3

Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists. This study defines evolution of coagulopathy in 10 pigs wi... Read More about Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs.

Phenotypic heterogeneity of peripheral monocytes in healthy dogs (2017)
Journal Article
Gibbons, N., Goulart, M. R., Chang, Y. M., Efstathiou, K., Purcell, R., Wu, Y., …Garden, O. A. (2017). Phenotypic heterogeneity of peripheral monocytes in healthy dogs. Veterinary Immunology and Immunopathology, 190, 26-30. https://doi.org/10.1016/j.vetimm.2017.06.007

Monocytes are key cells of the innate immune system. Their phenotypic and functional roles have been investigated in humans, mice and other animals, such as the rat, pig and cow. To date, detailed phenotypic analysis of monocytes has not been underta... Read More about Phenotypic heterogeneity of peripheral monocytes in healthy dogs.

Breed, Coat Color, and Hair Length as Risk Factors for Hyperthyroidism in Cats (2017)
Journal Article
Crossley, V. J., Debnath, A., Chang, Y. M., Fowkes, R. C., Elliott, J., & Syme, H. M. (2017). Breed, Coat Color, and Hair Length as Risk Factors for Hyperthyroidism in Cats. Journal of Veterinary Internal Medicine, 31(4), 1028-1034. https://doi.org/10.1111/jvim.14737

Hyperthyroidism is very common in older cats, but the etiopathogenesis is poorly understood. Decreased risk of hyperthyroidism has been reported in certain colorpoint breeds, and this observation previously has been hypothesized to result from relati... Read More about Breed, Coat Color, and Hair Length as Risk Factors for Hyperthyroidism in Cats.

Development and initial validation of a sensory threshold examination protocol (STEP) for phenotyping canine pain syndromes (2017)
Journal Article
Sanchis-Mora, S., Chang, Y. M., Abeyesinghe, S. M., Fisher, A., Volk, H. A., & Pelligand, L. (2017). Development and initial validation of a sensory threshold examination protocol (STEP) for phenotyping canine pain syndromes. Veterinary Anaesthesia and Analgesia, 44(3), 600-614. https://doi.org/10.1016/j.vaa.2016.09.004

Objective

To study feasibility and test-retest repeatability of a sensory threshold examination protocol (STEP) and report quantitative sensory threshold distributions in healthy dogs.

Study design

Prospective, observational, cohort study.... Read More about Development and initial validation of a sensory threshold examination protocol (STEP) for phenotyping canine pain syndromes.