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Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination (2015)
Journal Article
Natrajan, M. S., De La Fuente, A. G., Crawford, A. H., Lineham, E., Nuñez, V., Johnson, K. R., Wu, T., Fitzgerald, D. C., Ricote, M., Bielekova, B., & Franklin, R. J. (2015). Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination. Brain, 138(Pt12), 3581-97. https://doi.org/10.1093/brain/awv289

The efficiency of central nervous system remyelination declines with age. This is in part due to an age-associated decline in the phagocytic removal of myelin debris, which contains inhibitors of oligodendrocyte progenitor cell differentiation. In th... Read More about Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination.

Comparison of gabapentin versus topiramate on clinically affected dogs with Chiari-like malformation and syringomyelia (2015)
Journal Article
Plessas, I. N., Volk, H. A., Rusbridge, C., Vanhaesebrouck, A. E., & Jeffery, N. D. (2015). Comparison of gabapentin versus topiramate on clinically affected dogs with Chiari-like malformation and syringomyelia. Veterinary Record, 177(11), 288-288. https://doi.org/10.1136/vr.103234

To date there is no evidence-based data for efficacious treatment of neuropathic pain in dogs with Chiari-like malformation (CM) and syringomyelia (SM). The objective of this prospective cross-over study was to compare the effect of gabapentin versus... Read More about Comparison of gabapentin versus topiramate on clinically affected dogs with Chiari-like malformation and syringomyelia.