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Dissecting the Regulatory Microenvironment of a Large Animal Model of Non-Hodgkin Lymphoma: Evidence of a Negative Prognostic Impact of FOXP3+ T Cells in Canine B Cell Lymphoma (2014)
Journal Article
Pinheiro, D. Y., Chang, Y. M., Bryant, H., Szladovits, B., Dalessandri, T., Davison, L. J., …Garden, O. A. (2014). Dissecting the Regulatory Microenvironment of a Large Animal Model of Non-Hodgkin Lymphoma: Evidence of a Negative Prognostic Impact of FOXP3+ T Cells in Canine B Cell Lymphoma. PLoS ONE, 9(8), e105027. https://doi.org/10.1371/journal.pone.0105027

The cancer microenvironment plays a pivotal role in oncogenesis, containing a number of regulatory cells that attenuate the anti-neoplastic immune response. While the negative prognostic impact of regulatory T cells (Tregs) in the context of most sol... Read More about Dissecting the Regulatory Microenvironment of a Large Animal Model of Non-Hodgkin Lymphoma: Evidence of a Negative Prognostic Impact of FOXP3+ T Cells in Canine B Cell Lymphoma.

Comparison of air sac volume, lung volume and lung densities determined by use of computed tomography in conscious and anesthetized Humboldt penguins (Spheniscus humboldti) positioned in ventral, dorsal and right lateral recumbency (2014)
Journal Article
Nevitt, B. N., Langan, J. N., Adkesson, M. J., Mitchell, M. A., Henzler, M., & Drees, R. (2014). Comparison of air sac volume, lung volume and lung densities determined by use of computed tomography in conscious and anesthetized Humboldt penguins (Spheniscus humboldti) positioned in ventral, dorsal and right lateral recumbency. American Journal of Veterinary Research, 75(8), 739-45. https://doi.org/10.2460/ajvr.75.8.739

Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease (2014)
Journal Article
Kathrani, A., Lee, H., White, C., Catchpole, B., Murphy, A. M., German, A., …Allenspach, K. (2014). Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease. Veterinary Immunology and Immunopathology, 161(1-2), 32-41. https://doi.org/10.1016/j.vetimm.2014.06.003

The most important genetic associations that have been implicated to play a role in the etiology of Crohn's disease (CD) in humans are single nucleotide polymorphisms (SNPs) in nucleotide oligomerisation domain 2 (NOD2). The aim of this study was to... Read More about Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease.

Appearance of the canine meninges in subtraction magnetic resonance images (2014)
Journal Article
Lamb, C. R., Lam, R. W., Keenihan, E. K., & Frean, S. P. (2014). Appearance of the canine meninges in subtraction magnetic resonance images. https://doi.org/10.1111/vru.12166

The canine meninges are not visible as discrete structures in noncontrast magnetic resonance (MR) images, and are incompletely visualized in T1‐weighted, postgadolinium images, reportedly appearing as short, thin curvilinear segments with minimal enh... Read More about Appearance of the canine meninges in subtraction magnetic resonance images.

Prognostic value of early magnetic resonance imaging in dogs after traumatic brain injury: 50 cases (2014)
Journal Article
Beltran, E., Platt, S. R., McConnell, J. F., Dennis, R., Keys, D. A., & De Risio, L. (2014). Prognostic value of early magnetic resonance imaging in dogs after traumatic brain injury: 50 cases. Journal of Veterinary Internal Medicine, 28(4), 1256-62. https://doi.org/10.1111/jvim.12368

Retrospective study of dogs with TBI that underwent 1.5T MRI within 14 days after head trauma. MRI evaluators were blinded to the clinical presentation, and all images were scored based on an MRI grading system (Grade I [normal brain parenchyma] to G... Read More about Prognostic value of early magnetic resonance imaging in dogs after traumatic brain injury: 50 cases.

Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration (2014)
Journal Article
Kenward, H., Pelligand, L., & Elliott, J. (2014). Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration. Experimental Brain Research, 232(8), 2685-2697. https://doi.org/10.1007/s00221-014-3961-6

Cisplatin is a highly emetogenic cancer chemotherapy agent, which is often used to induce nausea and emesis in animal models. The cytotoxic properties of cisplatin also cause adverse events that negatively impact on animal welfare preventing repeated... Read More about Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration.

Oligodendrocyte progenitors: adult stem cells of the central nervous system (2014)
Journal Article
Crawford, A. H., Stockley, J. H., Tripathi, R. B., Richardson, W. D., & Franklin, R. J. (2014). Oligodendrocyte progenitors: adult stem cells of the central nervous system. Experimental Neurology, 260, 50-5. https://doi.org/10.1016/j.expneurol.2014.04.027

Oligodendrocyte progenitors (OPs) are a major proliferating cell population within the adult CNS. In response to myelin loss or increasing demand, OPs have the capacity to differentiate into mature, myelinating oligodendrocytes. The name ‘oligodendro... Read More about Oligodendrocyte progenitors: adult stem cells of the central nervous system.

Poloxomer 188 Has a Deleterious Effect on Dystrophic Skeletal Muscle Function (2014)
Journal Article
Terry, R. L., Kaneb, H. M., & Wells, D. J. (2014). Poloxomer 188 Has a Deleterious Effect on Dystrophic Skeletal Muscle Function. PLoS ONE, 9(3), e91221. https://doi.org/10.1371/journal.pone.0091221

Duchenne muscular dystrophy (DMD) is an X-linked, fatal muscle wasting disease for which there is currently no cure and limited palliative treatments. Poloxomer 188 (P188) is a tri-block copolymer that has been proposed as a potential treatment for c... Read More about Poloxomer 188 Has a Deleterious Effect on Dystrophic Skeletal Muscle Function.