Outputs (2505)

The development and use of Actiphage® to detect viable mycobacteria from bovine tuberculosis and Johne’s disease-infected animals (2019)
Journal Article
Swift, B. M. C., Meade, N., Barron, E. S., Bennett, M., Perehenic, T., Hughes, V., Stevenson, K., & Rees, C. E. D. (2019). The development and use of Actiphage® to detect viable mycobacteria from bovine tuberculosis and Johne’s disease-infected animals. Microbial Biotechnology, 13(3), 738-746. https://doi.org/10.1111/1751-7915.13518

Here, we describe the development of a method that exploits bacteriophage D29 as a lysis agent for efficient DNA extraction from low numbers of mycobacterial cells. This method (Actiphage®) used in combination with PCR achieved rapid and sensitive (L... Read More about The development and use of Actiphage® to detect viable mycobacteria from bovine tuberculosis and Johne’s disease-infected animals.

Decision tree machine learning applied to bovine tuberculosis risk factors to aid disease control decision making (2019)
Journal Article
Romero, M. P., Chang, Y. M., Brunton, L. A., Parry, J., Prosser, A., Upton, P., Rees, E., Tearne, O., Arnold, M., Stevens, K., & Drewe, J. A. (2019). Decision tree machine learning applied to bovine tuberculosis risk factors to aid disease control decision making. Preventive Veterinary Medicine, https://doi.org/10.1016/j.prevetmed.2019.104860

Identifying and understanding the risk factors for endemic bovine tuberculosis (TB) in cattle herds is critical for the control of this disease. Exploratory machine learning techniques can uncover complex non-linear relationships and interactions wit... Read More about Decision tree machine learning applied to bovine tuberculosis risk factors to aid disease control decision making.

Exploring the Risk Posed by Animals with An Inconclusive Reaction to the Bovine Tuberculosis Skin Test in England and Wales (2019)
Journal Article
May, E., Prosser, A., Downs, S. H., & Brunton, L. A. (2019). Exploring the Risk Posed by Animals with An Inconclusive Reaction to the Bovine Tuberculosis Skin Test in England and Wales. Veterinary Sciences, 6(4), 97. https://doi.org/10.3390/vetsci6040097

The single intradermal comparative cervical tuberculin (SICCT) test is the primary test for ante-mortem diagnosis of bovine tuberculosis (TB) in England and Wales. When an animal is first classified as an inconclusive reactor (IR) using this test, it... Read More about Exploring the Risk Posed by Animals with An Inconclusive Reaction to the Bovine Tuberculosis Skin Test in England and Wales.

Pathophysiology of Concussive Non-Penetrative Captive Bolt Stunning of Turkeys (2019)
Journal Article
Gibson, T. J., King, E., Spence, J., & Limon, G. (2019). Pathophysiology of Concussive Non-Penetrative Captive Bolt Stunning of Turkeys. Animals, 9(12), 1049. https://doi.org/10.3390/ani9121049

The non-penetrative captive bolt (NPCB) has been proposed as a more humane and practical alternative to constant voltage electrical stunning for small-scale seasonal turkey producers. This study evaluated the effectiveness of the CASH® Small Animal T... Read More about Pathophysiology of Concussive Non-Penetrative Captive Bolt Stunning of Turkeys.

Carprofen-induced depletion of proton motive force reverses TetK-mediated doxycycline resistance in methicillin-resistant Staphylococcus pseudintermedius (2019)
Journal Article
Magnowska, Z., Jana, B., Brochmann, R. P., Hesketh, A., Lametsch, R., De Gobba, C., & Guardabassi, L. (2019). Carprofen-induced depletion of proton motive force reverses TetK-mediated doxycycline resistance in methicillin-resistant Staphylococcus pseudintermedius. https://doi.org/10.1038/s41598-019-54091-4

We previously showed that doxycycline (DOX) and carprofen (CPF), a veterinary non-steroidal anti-inflammatory drug, have synergistic antimicrobial activity against methicillin-resistant Staphylococcus pseudintermedius (MRSP) carrying the tetracycline... Read More about Carprofen-induced depletion of proton motive force reverses TetK-mediated doxycycline resistance in methicillin-resistant Staphylococcus pseudintermedius.

Field Evaluation of Diagnostic Test Sensitivity and Specificity for Salmonid Alphavirus (SAV) Infection and Pancreas Disease (PD) in Farmed Atlantic salmon (Salmo salar L.) in Norway Using Bayesian Latent Class Analysis (2019)
Journal Article
Jansen, M. D., Guarracino, M., Carson, M., Modahl, I., Taksdal, T., Sindre, H., Brun, E., & Tavornpanich, S. (2019). Field Evaluation of Diagnostic Test Sensitivity and Specificity for Salmonid Alphavirus (SAV) Infection and Pancreas Disease (PD) in Farmed Atlantic salmon (Salmo salar L.) in Norway Using Bayesian Latent Class Analysis. Frontiers in Veterinary Science, 6, https://doi.org/10.3389/fvets.2019.00419

Impact of oral amoxicillin and amoxicillin/clavulanic acid treatment on bacterial diversity and ß-lactam resistance in the canine faecal microbiota (2019)
Journal Article
Espinosa-Gongora, C., Jessen, L. R., Kieler, I. N., Damborg, P., Bjørnvad, C. R., Gudeta, D. D., Pires dos Santos, T., Sablier-Gallis, F., Sayah-Jeanne, S., Corbel, T., Nevière, A., Hugon, P., Saint-Lu, N., de Gunzburg, J., & Guardabassi, L. (2019). Impact of oral amoxicillin and amoxicillin/clavulanic acid treatment on bacterial diversity and ß-lactam resistance in the canine faecal microbiota. Journal of Antimicrobial Chemotherapy, 75(2), 351-361. https://doi.org/10.1093/jac/dkz458

Development of Reporting Guidelines for Animal Health Surveillance—AHSURED (2019)
Journal Article
Comin, A., Grewar, J., Schaik, G. V., Schwermer, H., Paré, J., El Allaki, F., Drewe, J. A., Lopes Antunes, A. C., Estberg, L., Horan, M., Calvo-Artavia, F. F., Jibril, A. H., Martínez-Avilés, M., Van Der Stede, Y., Antoniou, S.-E., & Lindberg, A. (2019). Development of Reporting Guidelines for Animal Health Surveillance—AHSURED. Frontiers in Veterinary Science, 6, https://doi.org/10.3389/fvets.2019.00426

With the current trend in animal health surveillance toward risk-based designs and a gradual transition to output-based standards, greater flexibility in surveillance design is both required and allowed. However, the increase in flexibility requires... Read More about Development of Reporting Guidelines for Animal Health Surveillance—AHSURED.

Integrative concepts and practices of health in transdisciplinary social ecology (2019)
Journal Article
Assmuth, T., Chen, X., Degeling, C., Haahtela, T., Irvine, K. N., Keune, H., Kock, R. A., Rantala, S., Rüegg, S., & Vikström, S. (2019). Integrative concepts and practices of health in transdisciplinary social ecology. https://doi.org/10.1007/s42532-019-00038-y

Increasing recognition of interdependencies of the health of humans, other organisms and ecosystems, and of their importance to socio-ecological systems, necessitates application of integrative concepts such as One Health and EcoHealth. These concept... Read More about Integrative concepts and practices of health in transdisciplinary social ecology.

NF-κB2 signalling in enteroids modulates enterocyte responses to secreted factors from bone marrow-derived dendritic cells (2019)
Journal Article
Jones, L. G., Vaisa, A., Thompson, L. M., Ikuomola, F. I., Caamaño, J. H., Burkitt, M. D., Miyajima, F., Williams, J. M., Campbell, B. J., Pritchard, D. M., & Duckworth, C. A. (2019). NF-κB2 signalling in enteroids modulates enterocyte responses to secreted factors from bone marrow-derived dendritic cells. https://doi.org/10.1038/s41419-019-2129-5

Alternative pathway NF-κB signalling regulates susceptibility towards developing inflammatory bowel disease (IBD), colitis-associated cancer and sepsis-associated intestinal epithelial cell apoptosis and shedding. However, the cell populations respon... Read More about NF-κB2 signalling in enteroids modulates enterocyte responses to secreted factors from bone marrow-derived dendritic cells.