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Exploring Eimeria Genomes to Understand Population Biology: Recent Progress and Future Opportunities (2020)
Journal Article
Blake, D. P., Worthing, K., & Jenkins, M. C. (2020). Exploring Eimeria Genomes to Understand Population Biology: Recent Progress and Future Opportunities. Genes, 11(9),

Eimeria, protozoan parasites from the phylum Apicomplexa, can cause the enteric disease coccidiosis in all farmed animals. Coccidiosis is commonly considered to be most significant in poultry; due in part to the vast number of chickens produced in th... Read More about Exploring Eimeria Genomes to Understand Population Biology: Recent Progress and Future Opportunities.

Re-calculating the cost of coccidiosis in chickens (2020)
Journal Article
Blake, D. P., Knox, J., Dehaeck, B., Huntington, B., Rathinam, T., Ravipati, V., …Tomley, F. M. (2020). Re-calculating the cost of coccidiosis in chickens. Veterinary Research, 51(1), https://doi.org/10.1186/s13567-020-00837-2

Coccidiosis, caused by Eimeria species parasites, has long been recognised as an economically significant disease of chickens. As the global chicken population continues to grow, and its contribution to food security intensifies, it is increasingly i... Read More about Re-calculating the cost of coccidiosis in chickens.

Phylogenetic inference using cytochrome c oxidase subunit I (COI) in the poultry red mite, Dermanyssus gallinae in the United Kingdom relative to a European framework (2020)
Journal Article
Karp-Tatham, E., Küster, T., Angelou, A., Papadopoulos, E., Nisbet, A., Xia, D., …Tomley, F. (2020). Phylogenetic inference using cytochrome c oxidase subunit I (COI) in the poultry red mite, Dermanyssus gallinae in the United Kingdom relative to a European framework. Frontiers in Veterinary Science,

The poultry red mite (Dermanyssus gallinae), an obligatory blood feeding ectoparasite, is primarily associated with laying hens where it is estimated to cause losses of ~€231 million per annum to European farmers. Moderate to high infestation levels... Read More about Phylogenetic inference using cytochrome c oxidase subunit I (COI) in the poultry red mite, Dermanyssus gallinae in the United Kingdom relative to a European framework.

Vaccination with transgenic Eimeria tenella expressing Eimeria maxima AMA1 and IMP1 confers partial protection against high level E. maxima challenge in a broiler model of coccidiosis. (2020)
Journal Article
Pastor-Fernández, I., Sungwon, K., Marugán-Hernández, V., Soutter, F., Tomley, F., & Blake, D. (2020). Vaccination with transgenic Eimeria tenella expressing Eimeria maxima AMA1 and IMP1 confers partial protection against high level E. maxima challenge in a broiler model of coccidiosis. Parasites and Vectors,

Poultry coccidiosis is a parasitic enteric disease with a highly negative impact on chicken production. In-feed chemoprophylaxis remains the primary method of control, but the increasing ineffectiveness of anticoccidial drugs, and potential future re... Read More about Vaccination with transgenic Eimeria tenella expressing Eimeria maxima AMA1 and IMP1 confers partial protection against high level E. maxima challenge in a broiler model of coccidiosis..

Identification of Production Chain Risk Factors for Slaughterhouse Condemnation of Broiler Chickens’ (2020)
Journal Article
Buzdugan, S. N., Chang, Y. M., Huntington, B., Rushton, J., Guitian, J., Alarcon, P., & Blake, D. P. (2020). Identification of Production Chain Risk Factors for Slaughterhouse Condemnation of Broiler Chickens’. Preventive Veterinary Medicine, 105036. https://doi.org/10.1016/j.prevetmed.2020.105036

Slaughterhouse condemnation of broiler chickens results from identification of polymorphic pathological conditions during meat inspection from arrival and on theslaughter line. While conditions that result in condemnation are multifactorial, identifi... Read More about Identification of Production Chain Risk Factors for Slaughterhouse Condemnation of Broiler Chickens’.

Poultry Coccidiosis: Design and Interpretation of Vaccine Studies (2020)
Journal Article
Soutter, F., Werling, D., Tomley, F. M., & Blake, D. P. (2020). Poultry Coccidiosis: Design and Interpretation of Vaccine Studies. Frontiers in Veterinary Science, 7, https://doi.org/10.3389/fvets.2020.00101

Eimeria infection impacts upon chicken welfare and economic productivity of the poultry sector. Live coccidiosis vaccines for chickens have been available for almost 70 years, but the requirement to formulate blends of oocysts from multiple Eimeria s... Read More about Poultry Coccidiosis: Design and Interpretation of Vaccine Studies.

Evaluation of the Immunoprotective Potential of Recombinant Paraflagellar Rod Proteins of Trypanosoma evansi in Mice (2020)
Journal Article
Maharana, B. R., Sudhakar, N. R., Jawalagatti, V., Saravanan, B. C., Blake, D. P., & Tewari, A. K. (2020). Evaluation of the Immunoprotective Potential of Recombinant Paraflagellar Rod Proteins of Trypanosoma evansi in Mice. Vaccines, 8(1), 84. https://doi.org/10.3390/vaccines8010084

Trypanosomosis, caused by Trypanosoma evansi, is an economically significant disease of livestock. Systematic antigenic variation by the parasite has undermined prospects for the development of a protective vaccine that targets the immunodominant sur... Read More about Evaluation of the Immunoprotective Potential of Recombinant Paraflagellar Rod Proteins of Trypanosoma evansi in Mice.

Effects of reducing growth rate via diet dilution on bone mineralization, performance and carcass yield of coccidia-infected broilers (2019)
Journal Article
Oikeh, I., Sakkas, P., Taylor, J., Giannenas, I., Blake, D. P., & Kyriazakis, I. (2019). Effects of reducing growth rate via diet dilution on bone mineralization, performance and carcass yield of coccidia-infected broilers. Poultry Science, 98(11), 5477-5487. https://doi.org/10.3382/ps/pez400

Coccidiosis and rapid growth rate (GR) compromise bone mineralization in modern broilers. We tested the hypothesis that reducing GR via diet dilution during peak bone development will improve bone mineralization in both infected and uninfected broile... Read More about Effects of reducing growth rate via diet dilution on bone mineralization, performance and carcass yield of coccidia-infected broilers.