Francesca Soutter
A novel whole yeast-based subunit oral vaccine against Eimeria tenella in chickens
Soutter, Francesca; Werling, Dirk; Nolan, Matthew; Küster, Tatiana; Attree, Elizabeth; Marugán-Hernández, Virginia; Kim, Sungwon; Tomley, Fiona M.; Blake, Damer
Authors
Dirk Werling
Matthew Nolan
Tatiana Küster
Elizabeth Attree
Virginia Marugán-Hernández
Sungwon Kim
Fiona M. Tomley
Damer Blake
Abstract
Cheap, easy-to-produce oral vaccines are needed for control of coccidiosis in chickens to reduce the impact of this disease on welfare and economic performance. Saccharomyces cerevisiae yeast expressing three Eimeria tenella antigens were developed and delivered as heat-killed, freeze-dried whole yeast oral vaccines to chickens in four separate studies. After vaccination, E. tenella replication was reduced following low dose challenge (250 oocysts) in Hy-Line Brown layer chickens (p
Citation
Soutter, F., Werling, D., Nolan, M., Küster, T., Attree, E., Marugán-Hernández, V., …Blake, D. (2022). A novel whole yeast-based subunit oral vaccine against Eimeria tenella in chickens. Frontiers in Immunology, 13, Article 809711. https://doi.org/10.3389/fimmu.2022.809711
Journal Article Type | Article |
---|---|
Acceptance Date | Jan 12, 2022 |
Publication Date | Feb 2, 2022 |
Deposit Date | Oct 18, 2021 |
Publicly Available Date | Feb 2, 2022 |
Print ISSN | 1664-3224 |
Publisher | Frontiers Media |
Peer Reviewed | Peer Reviewed |
Volume | 13 |
Article Number | 809711 |
DOI | https://doi.org/10.3389/fimmu.2022.809711 |
Public URL | https://rvc-repository.worktribe.com/output/1551745 |
Publisher URL | https://www.frontiersin.org/articles/10.3389/fimmu.2022.809711/full |
Files
157 2022 Soutter Et Al Frontiers Imm Yeast 1
(60.5 Mb)
PDF
Publisher Licence URL
http://creativecommons.org/licenses/by/4.0/
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