The risk of pancreatic adenocarcinoma following SARS-CoV family infection

Sadrabadi, AE; Bereimipour, A; Jalili, A; Gholipurmalekabadi, M; Farhadihosseinabadi, B; Seifalian, AM

Abstract

COVID 19 disease has become a global catastrophe over the past year that has claimed the lives of over two million people around the world. Despite the introduction of vaccines against the disease, there is still a long way to completely eradicate it. There are concerns about the complications following infection with SARS-CoV-2. This research aimed to evaluate the possible correlation between infection with SARS-CoV viruses and cancer in an in-silico study model. To do this, the relevent dataset was selected from GEO database. Identification of differentially expressed genes among defined groups including SARS-CoV, SARS-dORF6, SARS-BatSRBD, and H1N1 were screened where the |Log FC|>= 1and p

Citation

Sadrabadi, A., Bereimipour, A., Jalili, A., Gholipurmalekabadi, M., Farhadihosseinabadi, B., & Seifalian, A. (2021). The risk of pancreatic adenocarcinoma following SARS-CoV family infection. Scientific Reports, 11(1), https://doi.org/10.1038/s41598-021-92068-4

• Journal Article Type: Article
• Acceptance Date: Jun 4, 2021
• Publication Date: 2021
• Deposit Date: Dec 23, 2021
• Publicly Available Date: Dec 23, 2021
• Publisher: Nature Research
• Peer Reviewed: Peer Reviewed
• Volume: 11
• Issue: 1
• DOI: https://doi.org/10.1038/s41598-021-92068-4
• Keywords: CANCER; EXPRESSION; GENES; SMAD3; CREB
• Public URL: https://rvc-repository.worktribe.com/output/1553870