Bacterial meningitis secondary to otogenic infection in 10 French bulldogs: A retrospective case series

Butterfield, S; Whittaker, D; Tabanez, J; Carrete, JC; Pitchford, C; Mattias, CRJ; Crawford, A; Rusbridge, C

Abstract

BackgroundThere is limited published information to guide the clinical management of bacterial meningitis/encephalitis in dogs. MethodsThis was a retrospective case series comprising 10 French bulldogs from two referral centres. The cases were diagnosed with bacterial meningitis/encephalitis suspected secondary to otogenic infection based on detection of abnormal fluid/soft tissue opacity within the middle/inner ear, associated meningeal/intracranial involvement through MRI, the findings of cerebro-spinal fluid (CSF) analysis suggestive of sepsis and/or clinical improvement following antibiosis. ResultsTen dogs were included (three female and seven male), with a median age of 60 months. Dogs presented with acute onset (median 2 days), progressive history of vestibular signs and/or intra-oral or cervical pain. Five dogs had gross signs of concurrent otitis externa. Common MRI findings included material within the tympanic bulla with adjacent meningeal enhancement. Analysis of CSF documented pleocytosis in all eight dogs, intracellular bacteria seen in three with positive bacteriological culture in two dogs. One dog was euthanised following diagnosis. Nine remaining dogs received antimicrobial therapy and six underwent surgical management. Three dogs treated surgically were neurologically normal within 2 weeks and the remaining three improved. Two dogs treated medically improved and one had complete resolution reported within a 4-week follow-up period. Study limitations include its retrospective nature and small sample size with minimal longer term follow-up. ConclusionsBacterial meningitis/encephalitis in French bulldogs can require both medical and surgical treatment to achieve a favourable outcome.

Citation

Butterfield, S., Whittaker, D., Tabanez, J., Carrete, J., Pitchford, C., Mattias, C., Crawford, A., & Rusbridge, C. (2023). Bacterial meningitis secondary to otogenic infection in 10 French bulldogs: A retrospective case series. Veterinary Record Open, 10(1), https://doi.org/10.1002/vro2.63

• Journal Article Type: Article
• Acceptance Date: May 8, 2023
• Online Publication Date: Jun 13, 2023
• Publication Date: 2023
• Deposit Date: Jan 17, 2024
• Publicly Available Date: Jan 19, 2024
• Journal: Veterinary Record Open
• Electronic ISSN: 2052-6113
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 10
• Issue: 1
• DOI: https://doi.org/10.1002/vro2.63
• Keywords: OTITIS-MEDIA; COMPLICATIONS; SIGNS; DOGS