Anatomical classification of feline congenital extrahepatic portosystemic shunts based on CT angiography: A SVSTS and VIRIES multi-institutional study in 231 cats

Weisse, C; Asano, K; Ishigaki, K; Lipscomb, V; Llanos, C; Zwingenberger, AL; Carroll, KA; Grosso, FRV; Stock, E; Buote, N; Aly, A; Murgia, D; Arai, S; Linden, AZ; Gordon, J; Manassero, M; Schwarz, T; Wallace, ML; Graham, J; Hardie, R; Chang, YF; Robbins, M; Bismuth, C; Karnia, J; Sterman, A; Saunders, A; Montinaro, V; Guarnera, I; Mclauchlan, G; Cerna, P; Maurin, MP; Aisa, J; An, AJL

Abstract

The prevalence of anatomical-based subtypes of feline congenital extrahepatic portosystemic shunts (EHPSS) has not been completely elucidated. The goal of this study was to use CT angiography to create an anatomical-based nomenclature system for feline congenital EHPSS. Additionally, subjective portal perfusion scores were generated to determine if intrinsic portal vein development was associated with different shunt conformations or patient age at the time of CT. The SVSTS and VIRIES list services were used to recruit cases. Data collected included patient DOB, gender, breed, weight, CT date, and reported diagnosis. Shunts were classified based upon (1) the shunt portal vessel(s) of origin, (2) the shunt systemic vessel(s) of insertion, and (3) any substantial portal vessels contributing to the shunt. Additionally, hepatic portal perfusion was subjectively scored between 1 (poor/none) and 5 (good/normal) based on the caliber of the intrahepatic PVs. A total of 264 CT scans were submitted from 29 institutions. Due to exclusion criteria, 33 (13%) were removed, leaving 231 CT scans to be included. Twenty-five different EHPSS anatomies were identified with five classifications accounting for 78% of all shunts (LGP [53%], LGC-post [11%], LCG [7%], LGC-pre [4%], and PC [4%]). Shunt origin involved the left gastric vein in 75% of the described classifications. Significant differences were identified among the five most common shunt types with respect to age at the time of CT scan (P = .002), breed (P < .001), and subjective portal perfusion score (P < .001). This refined anatomical classification system for feline EHPSS may enable improved understanding, treatment comparisons, and outcome prediction for cats with these anomalies.

Citation

Weisse, C., Asano, K., Ishigaki, K., Lipscomb, V., Llanos, C., Zwingenberger, A., …An, A. (2024). Anatomical classification of feline congenital extrahepatic portosystemic shunts based on CT angiography: A SVSTS and VIRIES multi-institutional study in 231 cats. Veterinary Radiology and Ultrasound, https://doi.org/10.1111/vru.13363

• Journal Article Type: Article
• Acceptance Date: Mar 17, 2024
• Online Publication Date: Apr 10, 2024
• Publication Date: 2024
• Deposit Date: Apr 15, 2024
• Print ISSN: 1058-8183
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• DOI: https://doi.org/10.1111/vru.13363
• Keywords: EHPSS; feline; portal anatomy; portal vein; portosystemic shunt; shunt anatomy; GASTRIC VEIN; DOGS; MORPHOLOGY