E11 AND RHOA SIGNALLING DURING OSTEOCYTOGENESIS
Journal Article
Prideaux, M., Pitsillides, A. A., Loveridge, N., & Farquharson, C. E11 AND RHOA SIGNALLING DURING OSTEOCYTOGENESIS. Calcified Tissue International, 83(1), 22-22
All Outputs (161)
A NOVEL PROFILE ANALYSIS OF METAPHYSEAL TRABECULAR BONE REVEALS A BIPHASIC DOSE-DEPENDENT RESPONSE TO ADMINISTERED BONE ACTIVE AGENTS
Journal Article
Salmon, P., Pitsillides, A. A., Tivesten, A., Moverare-Skrtic, S., Ohlsson, C., Oste, L., …Van T'Hof, R. A NOVEL PROFILE ANALYSIS OF METAPHYSEAL TRABECULAR BONE REVEALS A BIPHASIC DOSE-DEPENDENT RESPONSE TO ADMINISTERED BONE ACTIVE AGENTS. BONE, 43, S19-S19. https://doi.org/10.1016/j.bone.2008.07.060
Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis
Journal Article
Staines, K. A., Ikpegbu, E., Tornqvist, A. E., Dillon, S., Javaheri, B., Amin, A. K., …Farquharson, C. (in press). Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis. BMC Musculoskeletal Disorders, 20, https://doi.org/10.1186/s12891-019-2731-9Subchondral bone (SCB) thickening is one of the earliest detectable changes in osteoarthritic joints and is considered a potential trigger for subsequent articular cartilage degeneration. In this manuscript, we examine whether disruption to the SCB o... Read More about Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis.
The in vitro behaviour of canine osteoblasts derived from different bone types
Journal Article
Meeson, R. L., Perpétuo, I. P., Parsons, K. J., Orriss, I. R., Shah, M., Pitsillides, A. A., & Doube, M. (in press). The in vitro behaviour of canine osteoblasts derived from different bone types. BMC Veterinary Research, 15(114), https://doi.org/10.1186/s12917-019-1857-1
MURINE CRUCIATE LIGAMENT DEGENERATION AND MARKER EXPRESSION DURING OSTEOARTHRITIS
Journal Article
Ramos, L. D., Bou-Gharios, G., Pitsillides, A. A., Comerford, E. J., & Poulet, B. (in press). MURINE CRUCIATE LIGAMENT DEGENERATION AND MARKER EXPRESSION DURING OSTEOARTHRITIS. International Journal of Experimental Pathology, 98(6), A8-A9
Deficiency and Also Transgenic Overexpression of Timp-3 Both Lead to Compromised Bone Mass and Architecture In Vivo
Journal Article
Javaheri, B., Hopkinson, M., Poulet, B., Pollard, A. S., Shefelbine, S. J., Chang, Y. M., …Pitsillides, A. A. (in press). Deficiency and Also Transgenic Overexpression of Timp-3 Both Lead to Compromised Bone Mass and Architecture In Vivo. PLoS ONE, 11(8), e0159657. https://doi.org/10.1371/journal.pone.0159657
The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice
Journal Article
Gohin, S., Carriero, A., Chenu, C., Pitsillides, A. A., Arnett, T. R., & Marenzana, M. (in press). The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice. Cell Biochemistry and Function, 34(2), 52-62. https://doi.org/10.1002/cbf.3164
SPONTANEOUS HOME CAGE ACTIVITY IS SENSITIVE TO ANTI-NGF TREATMENT OR CAN BE LINKED TO JOINT STIFFNESS IN DIFFERENT MODELS OF SURGERY-INDUCED OSTEOARTHRITIS
Journal Article
Brenneis, C., Westhof, A., Duschek, J., Chang, Y. M., Pitsillides, A. A., Michaelis, M., …Guehring, H. SPONTANEOUS HOME CAGE ACTIVITY IS SENSITIVE TO ANTI-NGF TREATMENT OR CAN BE LINKED TO JOINT STIFFNESS IN DIFFERENT MODELS OF SURGERY-INDUCED OSTEOARTHRITIS. Osteoarthritis and Cartilage, 24, S498-S499. https://doi.org/10.1016/j.joca.2016.01.913
PENALIZED LINEAR DISCRIMINANT ANALYSIS REVEALS DIVERGENT GAIT PATTERNS IN THREE SURGICALLY-INDUCED OA MODELS
Journal Article
Chang, Y. M., Marsh-Dougerthy, J., Brenneis, C., Kleinschmidt, K., Michaelis, M., Guehring, H., …Pitsillides, A. A. PENALIZED LINEAR DISCRIMINANT ANALYSIS REVEALS DIVERGENT GAIT PATTERNS IN THREE SURGICALLY-INDUCED OA MODELS. Osteoarthritis and Cartilage, 24, S107-S108
Non-Invasive Mouse Models of Post-Traumatic Osteoarthritis
Journal Article
Christiansen, B. A., Guilak, F., Lockwood, K. A., Olson, S. A., Pitsillides, A. A., Sandell, L. J., …Haudenschild, D. R. (in press). Non-Invasive Mouse Models of Post-Traumatic Osteoarthritis. Osteoarthritis and Cartilage, 23(10), 1627-1638. https://doi.org/10.1016/j.joca.2015.05.009
MMP and TIMP temporal gene expression during osteocytogenesis
Journal Article
Prideaux, M., Staines, K. A., Jones, E. R., Riley, G. P., Pitsillides, A. A., & Farquharson, C. (in press). MMP and TIMP temporal gene expression during osteocytogenesis. Gene Expression Patterns, 18(1-2), 29-36. https://doi.org/10.1016/j.gep.2015.04.004Osteocytes within bone differentiate from osteoblast precursors which reside in a mineralised extracellular matrix (ECM). Fully differentiated osteocytes are critical for bone development and function but the factors that regulate this differentiatio... Read More about MMP and TIMP temporal gene expression during osteocytogenesis.
A HOLE IN THE HEAD; DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO
Journal Article
Akbareian, S. E., Fowkes, R. C., Macharia, R., Pitsillides, A. A., & McGonnell, I. M. A HOLE IN THE HEAD; DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO. International Journal of Experimental Pathology, 96(2), A21-A22
TRABECULAR ADAPTIVE RESPONSE TO LOADING IN AGED MICE IS RESTORED BY PRE-EXPOSURE TO SUPRAPHYSIOLOGICAL LOADS
Journal Article
Javaheri, B., Wood, M. J., Carriero, A., Shefelbine, S., & Pitsillides, A. A. TRABECULAR ADAPTIVE RESPONSE TO LOADING IN AGED MICE IS RESTORED BY PRE-EXPOSURE TO SUPRAPHYSIOLOGICAL LOADS. International Journal of Experimental Pathology, 96(2), A19-A19
GENDER DIFFERENCES OA PROGRESSION AND THEIR LONGITUDINAL GAIT CHANGES
Journal Article
Piles, M., De Souza, R., Poulet, B., Pitsillides, A. A., & Chang, Y. M. GENDER DIFFERENCES OA PROGRESSION AND THEIR LONGITUDINAL GAIT CHANGES. Osteoarthritis and Cartilage, 23, A128-A128
IDENTIFYING MECHANISMS AND EVOLUTIONARY IMPLICATIONS OF MECHANOSENSITIVE GROWTH IN THE EMBRYONIC LIMB SKELETON
Journal Article
Pollard, A. S., Charlton, B. G., McGonnell, I. M., & Pitsillides, A. A. IDENTIFYING MECHANISMS AND EVOLUTIONARY IMPLICATIONS OF MECHANOSENSITIVE GROWTH IN THE EMBRYONIC LIMB SKELETON. FASEB Journal, 29(1),
MECHANOSENSITIVITY OF EMBRYONIC LIMBS: MECHANO-SENSITIVE AND INSENSITIVE PERIODS OF GROWTH, DIFFERENTIAL SENSITIVITY BETWEEN LIMB ELEMENTS, AND THE UNDERPINNING MECHANISMS
Journal Article
Pollard, A. S., McGonnell, I. M., Chenu, C., Farquharson, C., & Pitsillides, A. A. MECHANOSENSITIVITY OF EMBRYONIC LIMBS: MECHANO-SENSITIVE AND INSENSITIVE PERIODS OF GROWTH, DIFFERENTIAL SENSITIVITY BETWEEN LIMB ELEMENTS, AND THE UNDERPINNING MECHANISMS. International Journal of Experimental Pathology, 96(2), A25-A25
SYSTEMATIZING MURINE MENISCAL AND LIGAMENT MODIFICATIONS DURING OSTEOARTHRITIS
Journal Article
Poulet, B., Bou-Gharios, G., & Pitsillides, A. A. SYSTEMATIZING MURINE MENISCAL AND LIGAMENT MODIFICATIONS DURING OSTEOARTHRITIS. Osteoarthritis and Cartilage, 23, A283-A283
FIBRILLIN-1 IS EXPRESSED IN CARTILAGE AND MUTATION LEADS TO OA DEVELOPMENT
Journal Article
Ramanayake, W., Jones, H., Orriss, I. R., Arnett, T., Pitsillides, A. A., Denton, C., …Poulet, B. FIBRILLIN-1 IS EXPRESSED IN CARTILAGE AND MUTATION LEADS TO OA DEVELOPMENT. International Journal of Experimental Pathology, 96(2), A4-A5
E11 PROTEIN STABILISATION BY PROTEASOME INHIBITION PROMOTES OSTEOCYTE DIFFERENTIATION AND MAY PROTECT AGAINST OSTEOARTHRITIS BONE PATHOLOGY
Journal Article
Staines, K. A., Prideaux, M., Hohenstein, P., Buttle, D. J., Pitsillides, A. A., & Farquharson, C. E11 PROTEIN STABILISATION BY PROTEASOME INHIBITION PROMOTES OSTEOCYTE DIFFERENTIATION AND MAY PROTECT AGAINST OSTEOARTHRITIS BONE PATHOLOGY. Osteoarthritis and Cartilage, 23, A57-A57
FAT-HIPPO SIGNALLING IN BONE DEVELOPMENT
Journal Article
Yiu, C. T., Zakaria, S., Shah, M., Mao, Y., Martin, T., Pitsillides, A. A., …Francis-West, P. FAT-HIPPO SIGNALLING IN BONE DEVELOPMENT. International Journal of Experimental Pathology, 96(2), A12-A12