K A Staines
Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis
Staines, K A; Ikpegbu, E; Tornqvist, A E; Dillon, S; Javaheri, B; Amin, A K; Clements, D N; Buttle, D J; Pitsillides, A A; Farquharson, C
Authors
E Ikpegbu
A E Tornqvist
S Dillon
B Javaheri
A K Amin
D N Clements
D J Buttle
A A Pitsillides
C Farquharson
Abstract
Subchondral bone (SCB) thickening is one of the earliest detectable changes in osteoarthritic joints and is considered a potential trigger for subsequent articular cartilage degeneration. In this manuscript, we examine whether disruption to the SCB osteocyte network contributes to the initiation and pathogenesis of osteoarthritis.
Citation
Staines, K. A., Ikpegbu, E., Tornqvist, A. E., Dillon, S., Javaheri, B., Amin, A. K., …Farquharson, C. (in press). Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis. BMC Musculoskeletal Disorders, 20, https://doi.org/10.1186/s12891-019-2731-9
| Journal Article Type | Article |
|---|---|
| Acceptance Date | Jul 19, 2019 |
| Deposit Date | Aug 9, 2019 |
| Publicly Available Date | Nov 20, 2020 |
| Journal | BMC MUSCULOSKELETAL DISORDERS |
| Publisher | BioMed Central |
| Peer Reviewed | Peer Reviewed |
| Volume | 20 |
| DOI | https://doi.org/10.1186/s12891-019-2731-9 |
| Public URL | https://rvc-repository.worktribe.com/output/1381226 |
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