Defining boundaries during joint cavity formation: going out on a limb
Journal Article
Lamb, K. J., Lewthwaite, J. C., Bastow, E. R., & Pitsillides, A. A. Defining boundaries during joint cavity formation: going out on a limb. International Journal of Experimental Pathology, 84(2), 55-67. https://doi.org/10.1046/j.1365-2613.2003.00338.x
All Outputs (161)
Diverse range of fixed positional deformities and bone growth restraint provoked by flaccid paralysis in embryonic chicks
Journal Article
Lamb, K. J., Lewthwaite, J. C., Lin, J. P., Simon, D., Kavanagh, E., Wheeler-Jones, C. P. D., & Pitsillides, A. A. Diverse range of fixed positional deformities and bone growth restraint provoked by flaccid paralysis in embryonic chicks. International Journal of Experimental Pathology, 84(4), 191-199
Methods for analyzing bone cell responses to mechanical loading using in vitro monolayer and organ culture models
Journal Article
Pitsillides, A. A., Das-Gupta, V., Simon, D., & Rawlinson, S. C. F. Methods for analyzing bone cell responses to mechanical loading using in vitro monolayer and organ culture models. https://doi.org/10.1385/1-59259-366-6%3A399
Hepatic guanylate cyclase activity is decreased in a model of cirrhosis: A quantitative cytochemistry study
Journal Article
Davies, N. A., Hodges, S. J., Pitsillides, A. A., Mookerjee, R. P., Jalan, R., & Mehdizadeh, S. Hepatic guanylate cyclase activity is decreased in a model of cirrhosis: A quantitative cytochemistry study. FEBS Letters, 580(8), 2123-2128. https://doi.org/10.1016/j.febslet.2006.02.080
Differential regulation of GDF-5 and FGF-2/4 by immobilisation in ovo exposes distinct roles in joint formation
Journal Article
Kavanagh, E., Church, V. L., Osborne, A. C., Lamb, K. J., Archer, C. W., Francis-West, P., & Pitsillides, A. A. Differential regulation of GDF-5 and FGF-2/4 by immobilisation in ovo exposes distinct roles in joint formation. Developmental Dynamics, 235(3), 826-834. https://doi.org/10.1002/dvdy.20679
A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation
Journal Article
Lewthwaite, J. C., Bastow, E. R., Lamb, K. J., Blenis, J., Wheeler-Jones, C. P. D., & Pitsillides, A. A. A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation. Journal of Biological Chemistry, 281(16), 11011-11018. https://doi.org/10.1074/jbc.M510680200
Cartilage oligomeric matrix protein and hyaluronan levels in synovial fluid from horses with osteoarthritis of the tarsometatarsal joint compared to a control population
Journal Article
Taylor, S. E., Weaver, M. P., Pitsillides, A. A., Wheeler, B. T., Wheeler-Jones, C. P. D., Shaw, D. J., & Smith, R. K. W. Cartilage oligomeric matrix protein and hyaluronan levels in synovial fluid from horses with osteoarthritis of the tarsometatarsal joint compared to a control population. Equine Veterinary Journal, 38(6), 502-507. https://doi.org/10.2746/042516406X156073
Osteocytes use estrogen receptor alpha to respond to strain but their ER alpha content is regulated by estrogen
Journal Article
Zaman, G., Jessop, H. L., Muzylak, M., De Souza, R. L., Pitsillides, A. A., Price, J. S., & Lanyon, L. L. Osteocytes use estrogen receptor alpha to respond to strain but their ER alpha content is regulated by estrogen. Journal of Bone and Mineral Research, 21(8), 1297-1306. https://doi.org/10.1359/JBMR.060504
Selective activation of the MEK-ERK pathway is regulated by mechanical stimuli in forming joints and promotes pericellular matrix formation
Journal Article
Bastow, E. R., Lamb, K. J., Lewthwaite, J. C., Osborne, A. C., Kavanagh, E., Wheeler-Jones, C. P. D., & Pitsillides, A. A. Selective activation of the MEK-ERK pathway is regulated by mechanical stimuli in forming joints and promotes pericellular matrix formation. Journal of Biological Chemistry, 280(12), 11749-11758. https://doi.org/10.1074/jbc.M414495200
Osteocytic expression of constitutive NO synthase isoforms in the femoral neck cortex: A case-control study of intracapsular hip fracture
Journal Article
Caballero-Alias, A. M., Loveridge, N., Pitsillides, A. A., Parker, M., Kaptoge, S., Lyon, A., & Reeve, J. Osteocytic expression of constitutive NO synthase isoforms in the femoral neck cortex: A case-control study of intracapsular hip fracture. Journal of Bone and Mineral Research, 20(2), 268-273. https://doi.org/10.1359/JBMR.041103
Non-invasive axial loading of mouse tibiae increases cortical bone fori-nation and modifies trabecular organization: A new model to study cortical and cancellous compartments in a single loaded element
Journal Article
De Souza, R. L., Matsuura, M., Eckstein, F., Rawlinson, S. C. F., Lanyon, L. E., & Pitsillides, A. A. Non-invasive axial loading of mouse tibiae increases cortical bone fori-nation and modifies trabecular organization: A new model to study cortical and cancellous compartments in a single loaded element. BONE, 37(6), 810-818. https://doi.org/10.1016/j.bone.2005.07.022
Sympathetic nervous system does not mediate the load-induced cortical new bone formation
Journal Article
De Souza, R. L., Pitsillides, A. A., Lanyon, L. E., Skerry, T. M., & Chenu, C. Sympathetic nervous system does not mediate the load-induced cortical new bone formation. Journal of Bone and Mineral Research, 20(12), 2159-2168. https://doi.org/10.1359/JBMR.050812
NOS isoforms in adult human osteocytes: Multiple pathways of NO regulation?
Journal Article
Caballero-Alias, A. M., Loveridge, N., Lyon, A., Das-Gupta, V., Pitsillides, A. A., & Reeve, J. NOS isoforms in adult human osteocytes: Multiple pathways of NO regulation?. Calcified Tissue International, 75(1), 78-84. https://doi.org/10.1007/s00223-003-0161-y
Quantitative cytochemical evidence for local increases in bone turnover at the acromial enthesis of the human coracoacromial ligament
Journal Article
Chambler, A., Rawlinson, S. C. F., Emery, R., & Pitsillides, A. A. Quantitative cytochemical evidence for local increases in bone turnover at the acromial enthesis of the human coracoacromial ligament
Osteoblast-like cells from estrogen receptor alpha knockout mice have deficient responses to mechanical strain
Journal Article
Jessop, H. L., Suswillo, R. F. L., Rawlinson, S. C. F., Zaman, G., Lee, K. C. L., Das-Gupta, V., Pitsillides, A. A., & Lanyon, L. E. Osteoblast-like cells from estrogen receptor alpha knockout mice have deficient responses to mechanical strain. Journal of Bone and Mineral Research, 19(6), 938-946
Acromial spur formation in patients with rotator cuff tears
Journal Article
Chambler, A. F. W., Pitsillides, A. A., & Emery, R. J. H. Acromial spur formation in patients with rotator cuff tears. Journal of Shoulder and Elbow Surgery, 12(4), 314-321. https://doi.org/10.1016/S1058-2746%2803%2900030-2
A mechanism underlying the movement requirement for synovial joint cavitation
Journal Article
Dowthwaite, G. P., Flannery, C. R., Flannelly, J., Lewthwaite, J. C., Archer, C. W., & Pitsillides, A. A. A mechanism underlying the movement requirement for synovial joint cavitation. Matrix Biology, 22(4), 311-322. https://doi.org/10.1016/S0945-053X%2803%2900037-4
Highly homologous Mycobacterium tuberculosis chaperonin 60 proteins with differential CD14 dependencies stimulate cytokine production by human monocytes through cooperative activation of p38 and ERK1/2 mitogen-activated protein kinases
Journal Article
Lewthwaite, J. C., Clarkin, C. E., Coates, A. R. M., Poole, S., Lawrence, R. A., Wheeler-Jones, C. P. D., Pitsillides, A. A., Singh, M., & Henderson, B. Highly homologous Mycobacterium tuberculosis chaperonin 60 proteins with differential CD14 dependencies stimulate cytokine production by human monocytes through cooperative activation of p38 and ERK1/2 mitogen-activated protein kinases. International Immunopharmacology, 7(2), 230-240. https://doi.org/10.1016/j.intimp.2006.10.005
Aging enhances a mechanically-induced reduction in tendon strength by an active process involving matrix metalloproteinase activity
Journal Article
Dudhia, J., Scott, C. M., Draper, E. R. C., Heinegard, D., Pitsillides, A. A., & Smith, R. K. W. Aging enhances a mechanically-induced reduction in tendon strength by an active process involving matrix metalloproteinase activity. Aging Cell, 6(4), 547-556. https://doi.org/10.1111/j.1474-9726.2007.00307.x
Identifying the cellular basis for reimplantation failure in repair of the rotator cuff
Journal Article
Simon, D. W. N., Clarkin, C. E., Das-Gupta, V., Rawlinson, S. C. F., Emery, R. J., & Pitsillides, A. A. Identifying the cellular basis for reimplantation failure in repair of the rotator cuff. https://doi.org/10.1302/0301-620x.90b5.20013We examined cultured osteoblasts derived from paired samples from the greater tuberosity and acromion from eight patients with large chronic tears of the rotator cuff. We found that osteoblasts from the tuberosity had no apparent response to mechanic... Read More about Identifying the cellular basis for reimplantation failure in repair of the rotator cuff.