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Regulation of UDP-Glucose Dehydrogenase Is Sufficient to Modulate Hyaluronan Production and Release, Control Sulfated GAG Synthesis, and Promote Chondrogenesis
Journal Article
Clarkin, C. E., Allen, S., Kuiper, N. J., Wheeler, B. T., Wheeler-Jones, C. P. D., & Pitsillides, A. A. Regulation of UDP-Glucose Dehydrogenase Is Sufficient to Modulate Hyaluronan Production and Release, Control Sulfated GAG Synthesis, and Promote Chondrogenesis. Journal of Cellular Physiology, 226(3), 749-761. https://doi.org/10.1002/jcp.22393

The effect of estradiol on COX-2, EP2, and EP4 mRNA expression and the extracellular matrix in the cervix of the hypogonadotrophic, ovariectomized ewe
Journal Article
Kershaw-Young, C. M., Scaramuzzi, R. J., McGowan, M. R., Pitsillides, A. A., Wheeler-Jones, C. P. D., & Khalid, M. The effect of estradiol on COX-2, EP2, and EP4 mRNA expression and the extracellular matrix in the cervix of the hypogonadotrophic, ovariectomized ewe. Theriogenology, 73(5), 620-628. https://doi.org/10.1016/j.theriogenology.2009.10.018

Increased Bone Mass, Altered Trabecular Architecture and Modified Growth Plate Organization in the Growing Skeleton of SOCS2 Deficient Mice
Journal Article
MacRae, V. E., Horvat, S., Pells, S. C., Dale, H., Collinson, R. S., Pitsillides, A. A., Ahmed, S. F., & Farquharson, C. Increased Bone Mass, Altered Trabecular Architecture and Modified Growth Plate Organization in the Growing Skeleton of SOCS2 Deficient Mice. Journal of Cellular Physiology, 218(2), 276-284. https://doi.org/10.1002/jcp.21593

Genetic selection for fast growth generates bone architecture characterised by enhanced periosteal expansion and limited consolidation of the cortices but a diminution in the early responses to mechanical loading
Journal Article
Rawlinson, S. C. F., Murray, D. H., Mosley, J. R., Wright, C. D. P., Bredl, J. C., Saxon, L. K., Loveridge, N., Leterrier, C., Constantin, P., Farquharson, C., & Pitsillides, A. A. Genetic selection for fast growth generates bone architecture characterised by enhanced periosteal expansion and limited consolidation of the cortices but a diminution in the early responses to mechanical loading. BONE, 45(2), 357-366. https://doi.org/10.1016/j.bone.2009.04.243

Hyaluronan synthesis and degradation in cartilage and bone
Journal Article
Bastow, E. R., Byers, S., Golub, S. B., Clarkin, C. E., Pitsillides, A. A., & Fosang, A. J. Hyaluronan synthesis and degradation in cartilage and bone. Cellular and Molecular Life Sciences, 65(3), 395-413. https://doi.org/10.1007/s00018-007-7360-z

Hyaluronan (HA) is a large but simple glycosaminoglycan composed of repeating D-glucuronic acid, beta 1-3 linked to N-acetyl-D-glucosamine beta 1-4, found in body fluids and tissues, in both intra- and extracellular compartments. Despite its structur... Read More about Hyaluronan synthesis and degradation in cartilage and bone.