Skip to main content

Research Repository

Advanced Search

All Outputs (37)

Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor
Journal Article
Dutton, L. C., Dudhia, J., Catchpole, B., Hodhkiss-Geere, H., Werling, D., & Connolly, D. J. (in press). Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor. https://doi.org/10.1038/s41598-018-31569-1

derived cells (CDCs) are a cardiac progenitor cell population, which have been shown to possess cardiac regenerative properties and can improve heart function in a variety of cardiac diseases. Studies in large animal models have predominantly focusse... Read More about Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor.

Pattern-recognition receptor mRNA expression and function in canine monocyte/macrophages and relevance to canine anal furunuclosis
Journal Article
House, A. K., Gregory, S. P., & Catchpole, B. Pattern-recognition receptor mRNA expression and function in canine monocyte/macrophages and relevance to canine anal furunuclosis. Veterinary Immunology and Immunopathology, 124(3-4), 230-240. https://doi.org/10.1016/j.vetimm.2008.03.012

Pattern-recognition receptors (PRRs) are important components of the innate immune system, enabling early detection of infection. Defective PRR function has been implicated in several infectious and immune-mediated diseases of human beings. including... Read More about Pattern-recognition receptor mRNA expression and function in canine monocyte/macrophages and relevance to canine anal furunuclosis.

Anti-Insulin Antibodies in Diabetic Dogs Before and After Treatment with Different Insulin Preparations
Journal Article
Davison, L. J., Walding, B. R., Herrtage, M. E., & Catchpole, B. Anti-Insulin Antibodies in Diabetic Dogs Before and After Treatment with Different Insulin Preparations. Journal of Veterinary Internal Medicine, 22(6), 1317-1325. https://doi.org/10.1111/j.1939-1676.2008.0194.x

Background: Anti-insulin antibodies (AIA) occur in diabetic dogs after insulin therapy, although their clinical significance is unclear. Hypothesis: Treatment of diabetic dogs with heterologous insulin is more likely to stimulate production of AIA th... Read More about Anti-Insulin Antibodies in Diabetic Dogs Before and After Treatment with Different Insulin Preparations.

Interleukin-2 and interferon-gamma mRNA expression in canine anal furunculosis lesions and the effect of ciclosporin therapy
Journal Article
Tivers, M. S., Catchpole, B., Gregory, S. P., & House, A. K. Interleukin-2 and interferon-gamma mRNA expression in canine anal furunculosis lesions and the effect of ciclosporin therapy. Veterinary Immunology and Immunopathology, 125(1/2), 31-36. https://doi.org/10.1016/j.vetimm.2008.04.018

German Shepherd Dogs have an increased incidence of anal furunculosis (AF), which is a disease characterized by inflammation and ulceration of the perianal tissues. Ciclosporin, an immunosuppressive drug, has been successfully used to treat AF, sugge... Read More about Interleukin-2 and interferon-gamma mRNA expression in canine anal furunculosis lesions and the effect of ciclosporin therapy.